Identifying immune signatures of sepsis to increase diagnostic accuracy in very preterm babies

Autor: A. Das, G. Ariyakumar, N. Gupta, S. Kamdar, A. Barugahare, D. Deveson-Lucas, S. Gee, K. Costeloe, M. S. Davey, P. Fleming, D. L. Gibbons

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract Bacterial infections are a major cause of mortality in preterm babies, yet our understanding of early-life disease-associated immune dysregulation remains limited. Here, we combine multi-parameter flow cytometry, single-cell RNA sequencing a

Externí odkaz: https://doaj.org/article/cf8475e2ea90428da183505fc8574ce4

How frequent is routine use of probiotics in UK neonatal units?

Autor: Justinas Teiserskas, Rachel Hutchinson, Lisa Szatkowski, Claire Caldwell, Katie Taylor, Emilie Seager, Catherine Longley, Rebecca Smith, Brandy Cox, Cheryl Battersby, Helen Lloyd, Aneurin Young, Deborah Davidson, Jennifer Peterson, Emma Williams, Kirti Gupta, Ahmed Mohamed, Paul Fleming, Tal Oryan, Mia Kahvo, Arameh Aghababaie, Janet Berrington, Michelle Fernandes, Neaha Patel, Jessica Farnan, Allan Jenkinson, Bushra Abdul-Malik, Lucinda Winckworth, Kate Costeloe, Christopher Freeman, Katie Evans, Jasmine Taylor, Mary-Rose Ballard, Rhiannon Jones, Rajkumar Dhandayuthapani, Caroline Fraser, James Stevens, Nuala Calder, Amy Grant, Moataz Badawy, Afza Sadiq, Manohar Joishy, Nathan Collicott, Naseem Sharif, Spandana Rupa Madabhushi, G Natasha, Joe McConville, Rhianna Netherton, Lizaveta Collins, Naomi Lin, Kouros Driscoll, Jonathan Talbot, Rosie Roots, Alison Hopper, Camilla James, Shreesh Bhat, Lauren Ferretti, Niha Peshimam, Benjamin Holter, Sion Glaze, Anna Waghorn, Shweta Dixit, Chibuko Ukeje, Shana Irvine, Fergus Harnden, Christine Lim, Neelakshi Ghosh, Eileen Foster, Swati Jha, Joanna O’Sullivan, Evangelia Myttaraki, Shreya Agrawal, Steve Abbey, Abdulhakim Abdurrazaq, Saud Ahmed, Faith Akano, Muhammad Rehan Akhtar, Oghenetekevwe Patrick Akpofure, Myriam Segovia Almiron, Namita Anand, Jessica Archibald, Harriet Aughey, Lynnlette Aung, Thandi Aung, Pramila Bade, Naomi Bell, Andrada Maria Bianu, Catherine Black, Gennie Booth, Karla Buerano, Chinnu Chandran, Shavin Chellen, Ruth Cousins, Leanne Dearman, Alshaimaa Eldeeb, Teim Eyo, Yasin Fatine, Poppy Flanagan, Abhrajit Giri, Saqib Hasan, Craig Haverstock, Jayne Hillier, Kate Hooper, Zoe Howard, Mais Ismail, Matilda Iverson, Sam Jay, Katie Jenkins, Carla Kantyka, Caroline Kargbo, Almutassem Kazkaz, Shelley Knights, Nikoletta Kottarakou, Carianne Lewis, Carys Mangan, Diane McCarter, Aodhan McGillian, Tasneem Modan, Maria Orford, Salil Pradhan, Patrycja Prusak, Ayesha Rahim, Daniel Ratnaraj, Naveed Shahzad, Adwa Shalabi, Claire Strauss, Jane Sundarsingh, Sumit Thankur, Toby Thenat, Alice Unsworth, Carl Van Heyningen, Elena Raluka Vlad

Publikováno v: BMJ Paediatrics Open, Vol 7, Iss 1 (2023)

Objective There is a lack of UK guidance regarding routine use of probiotics in preterm infants to prevent necrotising enterocolitis, late-onset sepsis and death. As practices can vary, we aimed to determine the current usage of probiotics within neo

Externí odkaz: https://doaj.org/article/a4706b9b6ad041239ac057e63d7aeec0

Intravenous antibiotics in preterm infants have a negative effect upon microbiome development throughout preterm life

Autor: R. A. Hutchinson, K. L. Costeloe, W. G. Wade, M. R. Millar, K. Ansbro, F. Stacey, P. F. Fleming

Publikováno v: Gut Pathogens, Vol 15, Iss 1, Pp 1-13 (2023)

Abstract Background Intestinal dysbiosis is implicated in the origins of necrotising enterocolitis and late-onset sepsis in preterm babies. However, the effect of modulators of bacterial growth (e.g. antibiotics) upon the developing microbiome is not

Externí odkaz: https://doaj.org/article/a6ef950d2042419bbede90a5f1979915

Aesthetician Role in Facial Plastic Surgery and Systemic Therapy for Healthy Skin

Autor: Costeloe, Anya, Newman, James

Publikováno v: In Facial Plastic Surgery Clinics of North America November 2023 31(4):557-566

The Effect of Unilateral Hearing Protection on Vocal Intensity With Varying Degrees of Background Noise

Autor: Rubin, Adam D. ^*, Codino, Juliana ^*, Costeloe, Anya, Johns, Michael M., Collum, Austin ^*, Bottalico, Pasquale

Publikováno v: In Journal of Voice November 2021 35(6):886-891