Výsledky vyhledávání - "Costas D. Arvanitis"

The roles of thermal and mechanical stress in focused ultrasound-mediated immunomodulation and immunotherapy for central nervous system tumors

Autor: Chulyong Kim, Michael Lim, Graeme F. Woodworth, Costas D. Arvanitis

Publikováno v: J Neurooncol

BACKGROUND: Focused ultrasound (FUS) is an emerging technology, offering the capability of tuning and prescribing thermal and mechanical treatments within the brain. While early works in utilizing this technology have mainly focused on maximizing the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5177c7e8b9284039c45884252828e2fa
https://doi.org/10.1007/s11060-022-03973-1

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Experimental Demonstration of Trans-Skull Volumetric Passive Acoustic Mapping With the Heterogeneous Angular Spectrum Approach

Autor: Costas D. Arvanitis, Scott Schoen, Pradosh Dash

Publikováno v: IEEE Trans Ultrason Ferroelectr Freq Control

Real-time, three-dimensional (3D), passive acoustic mapping (PAM) of microbubble dynamics during transcranial focused ultrasound (FUS) is essential for optimal treatment outcomes. The angular spectrum approach (ASA) potentially offers a very efficien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c4594d700b609b188482a60890e6c9
https://doi.org/10.1109/tuffc.2021.3125670

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Supplementary Figure 1 from Temporary Disruption of the Blood–Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques

Autor: Margaret S. Livingstone, Natalia Vykhodtseva, Costas D. Arvanitis, Nathan McDannold

PDF file - 107K, Figure S1: (A) Experimental setup. (B) Beam steering pattern used during volumetric sonication. The order of the nine "subsonications" is indicated. (C) Pulsing scheme used during volumetric sonication. Three 50 s sonications were de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5858810265fac8a2cb6830d95b5704b3
https://doi.org/10.1158/0008-5472.22392546

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Supplementary Figure 3 from Temporary Disruption of the Blood–Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques

Autor: Margaret S. Livingstone, Natalia Vykhodtseva, Costas D. Arvanitis, Nathan McDannold

PDF file - 130K, Figure S3: MRI and histological effects of sonication delivered at an exposure level that produced tissue damage in addition to BBB disruption. (A) T2*-weighted imaging after volumetric sonication (nine locations in a 3�3 grid) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411364f6c8b9704dd4355745a83f3f22
https://doi.org/10.1158/0008-5472.22392540

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Supplementary Figure 2 from Temporary Disruption of the Blood–Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques

Autor: Margaret S. Livingstone, Natalia Vykhodtseva, Costas D. Arvanitis, Nathan McDannold

PDF file - 349K, Figure S2: Histology after volumetric sonication in the hippocampus/LGN in monkey 4. This target was sonicated ~2h before the animal was sacrificed and in seven prior sessions over several months. (A) Contrast-enhanced T1-weighted MR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f286bea451c6b13ba2b8447886a527
https://doi.org/10.1158/0008-5472.22392543

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Closed-loop trans-skull ultrasound hyperthermia leads to improved drug delivery from thermosensitive drugs and promotes changes in vascular transport dynamics in brain tumors

Autor: Yutong Guo, Chulyong Kim, Anastasia Velalopoulou, Costas D. Arvanitis, Krishna Kumar Ramajayam, Anjan Motamarry, Muna Aryal, Dieter Haemmerich, Johannes Leisen

Publikováno v: Theranostics

Effective drug delivery in brain tumors remains a major challenge in oncology. Although local hyperthermia and stimuli-responsive delivery systems, such as thermosensitive liposomes, represent promising strategies to locally enhance drug delivery in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7901458449f3038b3fb275e0b71c0af9
https://doi.org/10.7150/thno.54630

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Acoustic source localization with the angular spectrum approach in continuously stratified media

Autor: Scott Schoen, Costas D. Arvanitis

Publikováno v: J Acoust Soc Am

The angular spectrum approach (ASA)---a fast, frequency domain method for calculation of the acoustic field---enables passive source localization and modeling forward propagation in homogeneous media with high computational efficiency. Here we show t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad488f1a176af68f347b1bb252c20e5b
https://doi.org/10.1121/10.0002095

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