Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Costas D Lallas"'
Autor:
Matthew J Schiewer, Amy C Mandigo, Nicolas Gordon, Fangjin Huang, Sanchaika Gaur, Renée de Leeuw, Shuang G Zhao, Joseph Evans, Sumin Han, Theodore Parsons, Ruth Birbe, Peter McCue, Christopher McNair, Saswati N Chand, Ylenia Cendon‐Florez, Peter Gallagher, Jennifer J McCann, Neermala Poudel Neupane, Ayesha A Shafi, Emanuela Dylgjeri, Lucas J Brand, Tapio Visakorpi, Ganesh V Raj, Costas D Lallas, Edouard J Trabulsi, Leonard G Gomella, Adam P Dicker, Wm. Kevin Kelly, Benjamin E Leiby, Beatrice Knudsen, Felix Y Feng, Karen E Knudsen
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp 1-20 (2018)
Abstract PARP‐1 holds major functions on chromatin, DNA damage repair and transcriptional regulation, both of which are relevant in the context of cancer. Here, unbiased transcriptional profiling revealed the downstream transcriptional profile of P
Externí odkaz:
https://doaj.org/article/044d966fd25b4793a1abaa4247be3583
Autor:
Connor McPartland, Andrew Salib, Joshua Banks, James R. Mark, Costas D. Lallas, Edouard J. Trabulsi, Leonard G. Gomella, Hanan Goldberg, Benjamin Leiby, Robert Den, Thenappan Chandrasekar
Publikováno v:
European Urology Open Science, Vol 63, Iss , Pp 52-61 (2024)
Background and objective: Radiation therapy has increasingly been used in the management of pelvic malignancies. However, the use of radiation continues to pose a risk of a secondary malignancy to its recipients. This study investigates the risk of s
Externí odkaz:
https://doaj.org/article/8fed90a672d84d9b917cc404d3a1c1ed
Autor:
Mark V Mishra, Michele Bennett, Armon Vincent, Olivia T Lee, Costas D Lallas, Edouard J Trabulsi, Leonard G Gomella, Adam P Dicker, Timothy N Showalter
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e68563 (2013)
Qualitative research aimed at identifying patient acceptance of active surveillance (AS) has been identified as a public health research priority. The primary objective of this study was to determine if analysis of a large-sample of anonymous interne
Externí odkaz:
https://doaj.org/article/e55631ed42984208a46b75d3a913e116
Autor:
Kerith R. Wang, Rishabh K. Simhal, Cassra B. Clark, Mark J. Mann, James R. Mark, Costas D. Lallas, Robert Den, Edouard J. Trabulsi
Publikováno v:
Advances in Urology, Vol 2024 (2024)
Objective. To examine one academic institution’s experiences with SpaceOAR placement, its associated complications, and periprocedural characteristics that affect outcomes for the purpose of quality improvement. Materials and Methods. We conducted
Externí odkaz:
https://doaj.org/article/7096467d775d495a968fa00435f3b442
Autor:
Thenappan Chandrasekar, Cassra B. Clark, Andrew Gomella, Corinne E. Wessner, Shuo Wang, Kibo Nam, Ji-Bin Liu, Flemming Forsberg, Andrej Lyshchik, Ethan Halpern, James R. Mark, Costas D. Lallas, Leonard G. Gomella, Leann Kania, Edouard J. Trabulsi, John R. Eisenbrey
Publikováno v:
European Urology Focus. 9:336-344
Management of complex renal cysts is guided by the Bosniak classification system, which may be inadequate for risk stratification of patients for intervention. Fractional tumor vascularity (FV) calculated from volumetric contrast-enhanced ultrasound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99161e233218548d28f1f534511a4df
https://doi.org/10.1016/j.euf.2022.10.004
https://doi.org/10.1016/j.euf.2022.10.004
Autor:
Marja T. Nevalainen, Bruno Calabretta, Nagarajan Pattabiraman, Vincent Njar, Gino Cingolani, Leonard G. Gomella, David T. Hoang, Hallgeir Rui, Guanjun Xia, Benjamin Leiby, Paolo Fortina, Adam Ertel, Shauna Blackmon, Elyse Ellsworth, Shilpa Gupta, Costas D. Lallas, Edouard Trabulsi, Peter A. McCue, Puranik Purushottamachar, Ayush Dagvadorj, Ravi K. Lokareddy, Marco De Dominici, Samanta A. Mariani, Jenny Vergalli, Lei Gu, Zhiyong Liao
Supplementary Table 4: Genes down-regulated (> 2-fold) by Stat5-shRNA and IST5-002 in K562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b04c76a8e28cb2743713cf60d3ca3b6
https://doi.org/10.1158/1535-7163.22501908.v1
https://doi.org/10.1158/1535-7163.22501908.v1
Autor:
Marja T. Nevalainen, Bruno Calabretta, Nagarajan Pattabiraman, Vincent Njar, Gino Cingolani, Leonard G. Gomella, David T. Hoang, Hallgeir Rui, Guanjun Xia, Benjamin Leiby, Paolo Fortina, Adam Ertel, Shauna Blackmon, Elyse Ellsworth, Shilpa Gupta, Costas D. Lallas, Edouard Trabulsi, Peter A. McCue, Puranik Purushottamachar, Ayush Dagvadorj, Ravi K. Lokareddy, Marco De Dominici, Samanta A. Mariani, Jenny Vergalli, Lei Gu, Zhiyong Liao
Supplementary Methods. Supplementary Figure 1. Chemical structures of the small molecule IST5-002 analogs. Supplementary Figure 2. IST5-002 inhibits phosphorylation of Stat5 in mouse and human breast cancer cells. Supplementary Figure 3. IST5-002 doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e3dfff6a37fe75ab4144213045f901
https://doi.org/10.1158/1535-7163.22501902.v1
https://doi.org/10.1158/1535-7163.22501902.v1
Autor:
Marja T. Nevalainen, Bruno Calabretta, Nagarajan Pattabiraman, Vincent Njar, Gino Cingolani, Leonard G. Gomella, David T. Hoang, Hallgeir Rui, Guanjun Xia, Benjamin Leiby, Paolo Fortina, Adam Ertel, Shauna Blackmon, Elyse Ellsworth, Shilpa Gupta, Costas D. Lallas, Edouard Trabulsi, Peter A. McCue, Puranik Purushottamachar, Ayush Dagvadorj, Ravi K. Lokareddy, Marco De Dominici, Samanta A. Mariani, Jenny Vergalli, Lei Gu, Zhiyong Liao
Supplementary Table 3: Genes up-regulated (> 2-fold) by Stat5-shRNA and IST5-002 in K562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b280acfc4448d6042e6bbbb7c7ad3891
https://doi.org/10.1158/1535-7163.22501914
https://doi.org/10.1158/1535-7163.22501914
Autor:
Marja T. Nevalainen, Bruno Calabretta, Nagarajan Pattabiraman, Vincent Njar, Gino Cingolani, Leonard G. Gomella, David T. Hoang, Hallgeir Rui, Guanjun Xia, Benjamin Leiby, Paolo Fortina, Adam Ertel, Shauna Blackmon, Elyse Ellsworth, Shilpa Gupta, Costas D. Lallas, Edouard Trabulsi, Peter A. McCue, Puranik Purushottamachar, Ayush Dagvadorj, Ravi K. Lokareddy, Marco De Dominici, Samanta A. Mariani, Jenny Vergalli, Lei Gu, Zhiyong Liao
Supplementary Table 5: IST5-002 regulation of known Stat5 target genes in K562 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f575425a25c708938c4d129d32c4ffb
https://doi.org/10.1158/1535-7163.22501896
https://doi.org/10.1158/1535-7163.22501896
Autor:
Marja T. Nevalainen, Bruno Calabretta, Nagarajan Pattabiraman, Vincent Njar, Gino Cingolani, Leonard G. Gomella, David T. Hoang, Hallgeir Rui, Guanjun Xia, Benjamin Leiby, Paolo Fortina, Adam Ertel, Shauna Blackmon, Elyse Ellsworth, Shilpa Gupta, Costas D. Lallas, Edouard Trabulsi, Peter A. McCue, Puranik Purushottamachar, Ayush Dagvadorj, Ravi K. Lokareddy, Marco De Dominici, Samanta A. Mariani, Jenny Vergalli, Lei Gu, Zhiyong Liao
Supplementary Table 2: Genes regulated by both Stat5-shRNA and IST5-002 in K562 cells, corresponding to the heatmap in Figure 2g.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf61bd52266069319368329bf1ecf51
https://doi.org/10.1158/1535-7163.22501899
https://doi.org/10.1158/1535-7163.22501899