Zobrazeno 1 - 10
of 64 629
pro vyhledávání: '"Costas A"'
Autor:
Claire Gallagher, George Moschonis, Katrina Lambert, Spyridon Kanellakis, Eva Karaglani, Niki Mourouti, Costas Anastasiou, Bircan Erbas, Yannis Manios
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Common mental disorders often emerge during childhood and adolescence, and their prevalence is disproportionately elevated among those affected by obesity. Early life growth patterns may provide a useful target for primordial prev
Externí odkaz:
https://doaj.org/article/4b742ec0876f47f78fa65463bc149781
Autor:
Nneka E. Mbah, Amy L. Myers, Peter Sajjakulnukit, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Heather Giza, Derek Dang, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zhu, Megan Radyk, Brooke Lavoie, Viveka Nand Yadav, Imhoi Koo, Andrew D. Patterson, Daniel R. Wahl, Luigi Franchi, Sameer Agnihotri, Carl J. Koschmann, Sriram Venneti, Costas A. Lyssiotis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract H3K27M diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), exhibit cellular heterogeneity comprising less-differentiated oligodendrocyte precursors (OPC)-like stem cells and more differentiated astrocyte (AC)-l
Externí odkaz:
https://doaj.org/article/b60128e341cf4e8c9deb69669f6c0187
Autor:
Yutong Guo, Hohyun Lee, Chulyong Kim, Christian Park, Akane Yamamichi, Pavlina Chuntova, Marco Gallus, Miguel O. Bernabeu, Hideho Okada, Hanjoong Jo, Costas Arvanitis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Microbubble-enhanced ultrasound provides a noninvasive physical method to locally overcome major obstacles to the accumulation of blood-borne therapeutics in the brain, posed by the blood-brain barrier (BBB). However, due to the highly nonli
Externí odkaz:
https://doaj.org/article/c4c8720a5c544fd09a3822eb2f6b69c6
Autor:
Mihaela Asaftei, Massimiliano Lucidi, Stefan Razvan Anton, Aikaterini-Flora Trompeta, Radu Hristu, Denis E. Tranca, Efstathios Fiorentis, Cristina Cirtoaje, Veronica Lazar, George A. Stanciu, Gabriella Cincotti, Paola Ayala, Costas A. Charitidis, Alina Holban, Paolo Visca, Stefan G. Stanciu
Publikováno v:
ACS Omega, Vol 9, Iss 31, Pp 33751-33764 (2024)
Externí odkaz:
https://doaj.org/article/bda4f2bcc1d3443686e9426b2d8354e7
Autor:
Erik R. Peterson, Peter Sajjakulnukit, Andrew J. Scott, Caleb Heaslip, Anthony Andren, Kari Wilder-Romans, Weihua Zhou, Sravya Palavalasa, Navyateja Korimerla, Angelica Lin, Alexandra O’Brien, Ayesha Kothari, Zitong Zhao, Li Zhang, Meredith A. Morgan, Sriram Venneti, Carl Koschmann, Nada Jabado, Costas A. Lyssiotis, Maria G. Castro, Daniel R. Wahl
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Background Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine 27 to methionine (H3K27M). DMG-H3K27M
Externí odkaz:
https://doaj.org/article/1951e061c7ab4540990fd8c2ffa35723
Autor:
He-Ling Wang, Jianying Zhang, Shu-qin Cao, Maria Jose Lagartos-Donate, Shi-qi Zhang, Sofie Lautrup, Zeping Hu, Costas A. Lyssiotis, Riekelt H. Houtkooper, Evandro F. Fang
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103428- (2024)
Summary: Here, we present a NAD+/NADH detection assay for evaluating NAD+, NADH, and NAD+/NADH ratio across diverse biological models, including Caenorhabditis elegans, mouse muscle tissue, mouse whole blood, and human whole blood. We describe steps
Externí odkaz:
https://doaj.org/article/1cc870debf0a4ba188e1b13511719798
Autor:
Mahya Jodeiri Rad, Costas Armenakis
Publikováno v:
Canadian Journal of Remote Sensing, Vol 50, Iss 1 (2024)
Image segmentation using supervised learning algorithms usually requires large amounts of annotated training data, while urban datasets frequently contain unbalanced classes leading to poor detection of under-represented classes. We investigate the u
Externí odkaz:
https://doaj.org/article/38db7e0847be475d97aab3755b94b479
Autor:
Mack B. Reynolds, Benjamin Klein, Michael J. McFadden, Norah K. Judge, Hannah E. Navarrete, Britton C Michmerhuizen, Dominik Awad, Tracey L. Schultz, Paul W. Harms, Li Zhang, Teresa R. O’Meara, Jonathan Z. Sexton, Costas A. Lyssiotis, J. Michelle Kahlenberg, Mary X. O’Riordan
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114607- (2024)
Summary: Macrophage metabolic plasticity is central to inflammatory programming, yet mechanisms of coordinating metabolic and inflammatory programs during infection are poorly defined. Here, we show that type I interferon (IFN) temporally guides meta
Externí odkaz:
https://doaj.org/article/b80ebd8315f645efa79adec43f6f9598
Autor:
Anastasia Spartiati, Anna Demetriou, V. Scoutellas, Costas A. Christophi, Konstantinos C. Makris
Publikováno v:
Cancer Reports, Vol 7, Iss 6, Pp n/a-n/a (2024)
Abstract Background Cancer is one of the leading causes of morbidity and mortality, worldwide. Little information is available for the temporal trends of cancer in the Mediterranean region, including Cyprus. Aims We aimed to analyze cancer incidence
Externí odkaz:
https://doaj.org/article/d25885026e0c490fad298d20070f1e18
Autor:
Andria Christodoulou, Costas A. Christophi, Mercedes Sotos-Prieto, Steven Moffatt, Longgang Zhao, Stefanos N. Kales, James R. Hébert
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionDietary choices play a crucial role in influencing systemic inflammation and the eventual development of cardiovascular diseases (CVD). The Dietary Inflammatory Index (DII®) is a novel tool designed to assess the inflammatory potential o
Externí odkaz:
https://doaj.org/article/aa0073a98522465aa59013a3f5fc8a16