Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Costanza Annamaria Lagrasta"'
Autor:
Silvia La Monica, Roberta Minari, Daniele Cretella, Lisa Flammini, Claudia Fumarola, Mara Bonelli, Andrea Cavazzoni, Graziana Digiacomo, Maricla Galetti, Denise Madeddu, Angela Falco, Costanza Annamaria Lagrasta, Anna Squadrilli, Elisabetta Barocelli, Alessandro Romanel, Federico Quaini, Pier Giorgio Petronini, Marcello Tiseo, Roberta Alfieri
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Abstract Background The third generation Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) osimertinib has been initially approved for T790M positive Non-Small Cell Lung Cancer (NSCLC) and more recently for first-line treatment
Externí odkaz:
https://doaj.org/article/0332689cda2e4440a52ebd48a300166b
Autor:
Valentina Coccè, Silvia La Monica, Mara Bonelli, Giulio Alessandri, Roberta Alfieri, Costanza Annamaria Lagrasta, Denise Madeddu, Caterina Frati, Lisa Flammini, Daniela Lisini, Angela Marcianti, Eugenio Parati, Francesca Paino, Aldo Giannì, Giampietro Farronato, Angela Falco, Lorenzo Spaggiari, Francesco Petrella, Augusto Pessina
Publikováno v:
Cells, Vol 10, Iss 6, p 1427 (2021)
Background: Malignant Pleural Mesothelioma (MPM) is an aggressive tumor that has a significant incidence related to asbestos exposure with no effective therapy and poor prognosis. The role of mesenchymal stromal cells (MSCs) in cancer is controversia
Externí odkaz:
https://doaj.org/article/5043b2f15724475d949474c94b0dbd6f
Autor:
Bianca Maria Rotoli, Amelia Barilli, Rossana Visigalli, Francesca Ferrari, Caterina Frati, Costanza Annamaria Lagrasta, Maria Di Lascia, Benedetta Riccardi, Paola Puccini, Valeria Dall’Asta
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3190 (2020)
The ATP-binding cassette (ABC) transporters P-glycoprotein (MDR1/ABCB1), multidrug resistance-associated protein 1 (MRP1/ABCC1), and breast cancer resistance protein (BCRP/ABCG2) play a crucial role in the translocation of a broad range of drugs; dat
Externí odkaz:
https://doaj.org/article/b9453f0363c0484982fad5fba4f7464a
Autor:
Mara Bonelli, Silvia La Monica, Valentina Coccé, Giulio Alessandri, Roberta Alfieri, Costanza Annamaria Lagrasta, Caterina Frati, Lisa Flammini, Aldo Gianni, Francesco Petrella, Francesca Paino, Augusto Pessina
Publikováno v:
Current Cancer Drug Targets. 23:663-668
Background: Malignant pleural mesothelioma is a pathology with no effective therapy and a poor prognosis. Our previous study demonstrated an in vitro inhibitory effect on mesothelioma cell lines of both the lysate and secretome of adipose tissue-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf02ed5637f59337d0f21237e9a0c07f
https://doi.org/10.2174/1568009623666230201092302
https://doi.org/10.2174/1568009623666230201092302
Autor:
Andrea Ardizzoni, Pier Giorgio Petronini, Marcello Tiseo, Claudia Fumarola, Pietro Rossetti, Angela Falco, Costanza Annamaria Lagrasta, Caterina Frati, Denise Madeddu, Cristina Caffarra, Daniele Cretella, Maricla Galetti, Silvia La Monica, Federico Quaini, Roberta R. Alfieri, Francesca Saccani, Andrea Cavazzoni, Mara A. Bonelli
Supplementary Tables S1-S5. Table S1: Antiproliferative effects of PI3K inhibitors on SKMES-1 and PIK3CA amplified/mutated clones Tables S2-S4: densitometric analysis of Western blotting of Figure 1D Table S5: Antiproliferative effects of PI3K inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e69b71948c3fa52cb952394674c5eaf
https://doi.org/10.1158/1535-7163.22502805.v1
https://doi.org/10.1158/1535-7163.22502805.v1
Autor:
Andrea Ardizzoni, Pier Giorgio Petronini, Marcello Tiseo, Claudia Fumarola, Pietro Rossetti, Angela Falco, Costanza Annamaria Lagrasta, Caterina Frati, Denise Madeddu, Cristina Caffarra, Daniele Cretella, Maricla Galetti, Silvia La Monica, Federico Quaini, Roberta R. Alfieri, Francesca Saccani, Andrea Cavazzoni, Mara A. Bonelli
Supplementary Figures S1-S5. Figure S1: p-AKT levels in PIK3CA transfected clones Figure S2: Induction of cell death after treatment with PI3K inhibitors Figure S3: Time course evaluation of PI3K/AKT/mTOR pathway activity after exposure to PI3K inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02930cdb13d557e127cf18f88f1ab0ab
https://doi.org/10.1158/1535-7163.22502811
https://doi.org/10.1158/1535-7163.22502811
Autor:
Marcello Tiseo, Federico Quaini, Franco Aversa, Konrad Urbanek, Andrea Ardizzoni, Enrico Maria Silini, Michele Veneziani, Luca Ampollini, Roberta Alfieri, Caterina Frati, Rocchina Vilella, Chiara Mangiaracina, Bruno Lorusso, Costanza Annamaria Lagrasta, Giovanna Armani, Francesco Sogni, Matteo Goldoni, Giovanni Bocchialini, Angela Falco, Denise Madeddu, Giulia Mazzaschi
Purpose: The success of immune checkpoint inhibitors strengthens the notion that tumor growth and regression are immune regulated. To determine whether distinct tissue immune microenvironments differentially affect clinical outcome in non–small cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283f8b8062f0e685ada4fa6c649dee5b
https://doi.org/10.1158/1078-0432.c.6526485
https://doi.org/10.1158/1078-0432.c.6526485
Autor:
Marcello Tiseo, Federico Quaini, Franco Aversa, Konrad Urbanek, Andrea Ardizzoni, Enrico Maria Silini, Michele Veneziani, Luca Ampollini, Roberta Alfieri, Caterina Frati, Rocchina Vilella, Chiara Mangiaracina, Bruno Lorusso, Costanza Annamaria Lagrasta, Giovanna Armani, Francesco Sogni, Matteo Goldoni, Giovanni Bocchialini, Angela Falco, Denise Madeddu, Giulia Mazzaschi
Clinicopathological correlations. Figure S1: PD-L1 Expression and Clinicopathologic Parameters; Figure S2: PD-L1 Expression and TILs; Figure S3: TILs and Clinicopathological Parameters; Figure S4: NSCLC Immune Microenvironments Based on PD-L1 and TIL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c040adf5602292e369f263808dee5e
https://doi.org/10.1158/1078-0432.22466943.v1
https://doi.org/10.1158/1078-0432.22466943.v1
Autor:
Marcello Tiseo, Federico Quaini, Franco Aversa, Konrad Urbanek, Andrea Ardizzoni, Enrico Maria Silini, Michele Veneziani, Luca Ampollini, Roberta Alfieri, Caterina Frati, Rocchina Vilella, Chiara Mangiaracina, Bruno Lorusso, Costanza Annamaria Lagrasta, Giovanna Armani, Francesco Sogni, Matteo Goldoni, Giovanni Bocchialini, Angela Falco, Denise Madeddu, Giulia Mazzaschi
Table S1. Antibodies for Immunohistochemistry; Table S2. Magnitude of Sampling; Table S3. Magnitude of Sampling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2a0509ac01b82b62116d6b0a50cff9
https://doi.org/10.1158/1078-0432.22466940
https://doi.org/10.1158/1078-0432.22466940
Autor:
Cocce', V., Silvia La Monica, Mara, B., Giulio, A., Roberta, A., Costanza Annamaria Lagrasta, Caterina, F., Lisa, F., Aldo, G., Doneda, L., Petrella, F., Paino, F., Pessina, A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1261::7df5bb3b97a9e82e57786932b573dd46
https://hdl.handle.net/2434/943652
https://hdl.handle.net/2434/943652