Sleeve Gastrectomy-Induced Weight Loss Increases Insulin Clearance in Obese Mice.

Autor: Soares GM; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil., Lopes LES; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil.; Laboratory of Endocrine Physiology and Metabolism, Biological Sciences and Health Center, Western Paraná State University (UNIOESTE), Cascavel 85819-110, Brazil., Balbo SL; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil.; Laboratory of Endocrine Physiology and Metabolism, Biological Sciences and Health Center, Western Paraná State University (UNIOESTE), Cascavel 85819-110, Brazil., Marmentini C; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil., Bronczek GA; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil., Kurauti MA; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil., Bonfleur ML; Laboratory of Endocrine Physiology and Metabolism, Biological Sciences and Health Center, Western Paraná State University (UNIOESTE), Cascavel 85819-110, Brazil., Velloso LA; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil., Carneiro EM; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil., Boschero AC; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil., Costa-Júnior JM; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-864, Brazil.; Center for Diabetes Research, Division of Endocrinology, Erasmus Hospital, Universite Libre de Bruxelles (ULB), 1070 Brussels, Belgium.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 15; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 15.

Paternal Exercise Improves the Metabolic Health of Offspring via Epigenetic Modulation of the Germline.

Autor: Costa-Júnior JM; Department of Structural and Functional Biology, Biology Institute, State University of Campinas (Unicamp), Campinas 13083-864, SP, Brazil., Ferreira SM; Department of Structural and Functional Biology, Biology Institute, State University of Campinas (Unicamp), Campinas 13083-864, SP, Brazil., Kurauti MA; Department of Structural and Functional Biology, Biology Institute, State University of Campinas (Unicamp), Campinas 13083-864, SP, Brazil., Bernstein DL; Department of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Ruano EG; Diabetes and Obesity Laboratory, August Pi I Sunyer Biomedical Research Institute (IDIBAPS), Campus Casanova, Casanova, 14308036 Barcelona, Spain.; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), 14308036 Barcelona, Spain., Kameswaran V; Department of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Schug J; Department of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Freitas-Dias R; Department of Structural and Functional Biology, Biology Institute, State University of Campinas (Unicamp), Campinas 13083-864, SP, Brazil., Zoppi CC; Department of Structural and Functional Biology, Biology Institute, State University of Campinas (Unicamp), Campinas 13083-864, SP, Brazil., Boschero AC; Department of Structural and Functional Biology, Biology Institute, State University of Campinas (Unicamp), Campinas 13083-864, SP, Brazil., Oliveira CAM; Department of Biosciences, Federal University of Sao Paulo, Santos 11015-020, SP, Brazil., Santos GJ; Islet Biology and Metabolism Lab., Department of Physiological Sciences, Center for Biological Sciences, University Federal of Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brazil., Carneiro EM; Department of Structural and Functional Biology, Biology Institute, State University of Campinas (Unicamp), Campinas 13083-864, SP, Brazil., Kaestner KH; Department of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 21; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 21.

ARHGAP21 Acts as an Inhibitor of the Glucose-Stimulated Insulin Secretion Process.

Autor: Ferreira SM; Obestity and Comorbidities Research Center/Biology Institute, University State of Campinas (UNICAMP), Campinas, Brazil., Costa-Júnior JM; Obestity and Comorbidities Research Center/Biology Institute, University State of Campinas (UNICAMP), Campinas, Brazil., Kurauti MA; Departament Physiological Sciences, University State of Maringá (UEM), Maringá, Brazil., Leite NC; Obestity and Comorbidities Research Center/Biology Institute, University State of Campinas (UNICAMP), Campinas, Brazil., Ortis F; Department of Cellular Biology and Development, Institute of Biomedical Sciences, University State of São Paulo (USP), São Paulo, Brazil., Rezende LF; Departament of Physiopathology, University State of Montes Claros (UNIMONTES), Montes Claros, Brazil., Barbosa HC; Obestity and Comorbidities Research Center/Biology Institute, University State of Campinas (UNICAMP), Campinas, Brazil., Boschero AC; Obestity and Comorbidities Research Center/Biology Institute, University State of Campinas (UNICAMP), Campinas, Brazil., Santos GJ; Departament of Physiological Sciences, Center for Biological Sciences, University Federal of Santa Catarina (UFSC), Florianópolis, Brazil.

Publikováno v: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2020 Nov 26; Vol. 11, pp. 599165. Date of Electronic Publication: 2020 Nov 26 (Print Publication: 2020).

Whole-Body ARHGAP21-Deficiency Improves Energetic Homeostasis in Lean and Obese Mice.

Autor: Soares GM; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil., Zangerolamo L; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil., Costa-Júnior JM; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil., Vettorazzi JF; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil., Carneiro EM; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil., Saad ST; Hematology and Hemotherapy Center, University of Campinas, HEMOCENTRO-UNICAMP, Campinas, Brazil., Boschero AC; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil., Barbosa-Sampaio HC; Obesity and Comorbidities Research Center, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, Brazil.

Publikováno v: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2019 May 29; Vol. 10, pp. 338. Date of Electronic Publication: 2019 May 29 (Print Publication: 2019).

Whole body ARHGAP21 reduction improves glucose homeostasis in high-fat diet obese mice.

Autor: Soares GM; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, UNICAMP, Campinas, São Paulo, Brazil., Zangerolamo L; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, UNICAMP, Campinas, São Paulo, Brazil., Azevedo EG; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, UNICAMP, Campinas, São Paulo, Brazil., Costa-Júnior JM; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, UNICAMP, Campinas, São Paulo, Brazil., Carneiro EM; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, UNICAMP, Campinas, São Paulo, Brazil., Saad ST; Hematology and Hemotherapy Center, University of Campinas, HEMOCENTRO-UNICAMP, Campinas, São Paulo, Brazil., Boschero AC; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, UNICAMP, Campinas, São Paulo, Brazil., Barbosa-Sampaio HC; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, UNICAMP, Campinas, São Paulo, Brazil.

Publikováno v: Journal of cellular physiology [J Cell Physiol] 2018 Sep; Vol. 233 (9), pp. 7112-7119. Date of Electronic Publication: 2018 Mar 25.