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Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease

Autor: Gaspar, Luís, Coron, Ross P., KongThoo Lin, Paul, Costa, David M., Perez-Cabezas, Begoña, Tavares, Joana, Roura-Ferrer, Meritxell, Ramos, Isbaal, Ronin, Céline, Major, Louise L., Ciesielski, Fabrice, Pemberton, Iain K., MacDougall, Jane, Ciapetti, Paola, Smith, Terry K., Cordeiro-da-Silva, Anabela

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006180 (2018)
PLoS Neglected Tropical Diseases

Chagas disease remains one of the most neglected diseases in the world despite being the most important parasitic disease in Latin America. The characteristic chronic manifestation of chagasic cardiomyopathy is the region’s leading cause of heart-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::155a97605da76f5b6f4e8329a66e3953

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Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.

Autor: Gaspar L; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC-Instituto de Biologia Molecular e Celular, Parasite Disease Group, Porto, Portugal., Coron RP; Biomedical Sciences Research Complex, The University, St. Andrews, Fife. Scotland, United Kingdom., KongThoo Lin P; Robert Gordon University, School of Pharmacy and Life Sciences, Aberdeen, Scotland, United Kingdom., Costa DM; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC-Instituto de Biologia Molecular e Celular, Parasite Disease Group, Porto, Portugal., Perez-Cabezas B; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC-Instituto de Biologia Molecular e Celular, Parasite Disease Group, Porto, Portugal., Tavares J; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC-Instituto de Biologia Molecular e Celular, Parasite Disease Group, Porto, Portugal., Roura-Ferrer M; Innoprot SL, Derio, Spain., Ramos I; Innoprot SL, Derio, Spain., Ronin C; NovAliX, Illkirch Cedex, France., Major LL; Biomedical Sciences Research Complex, The University, St. Andrews, Fife. Scotland, United Kingdom., Ciesielski F; NovAliX, Illkirch Cedex, France., Pemberton IK; Photeomix Protein Discovery, IP Research Consulting, Noisy Le Grand, France., MacDougall J; Photeomix Protein Discovery, IP Research Consulting, Noisy Le Grand, France., Ciapetti P; NovAliX, Illkirch Cedex, France., Smith TK; Biomedical Sciences Research Complex, The University, St. Andrews, Fife. Scotland, United Kingdom., Cordeiro-da-Silva A; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.; IBMC-Instituto de Biologia Molecular e Celular, Parasite Disease Group, Porto, Portugal.; Departmento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Jan 22; Vol. 12 (1), pp. e0006180. Date of Electronic Publication: 2018 Jan 22 (Print Publication: 2018).