Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures.

Autor: Cossec JC; Nuclear Organization and Oncogenesis Unit, Department of Cell Biology and Infection, Equipe Labellisée Ligue Nationale Contre le Cancer, Institut Pasteur, Université Paris Cité, 75015 Paris, France; INSERM, U993, 75015 Paris, France. Electronic address: jcossec@pasteur.fr., Traboulsi T; Nuclear Organization and Oncogenesis Unit, Department of Cell Biology and Infection, Equipe Labellisée Ligue Nationale Contre le Cancer, Institut Pasteur, Université Paris Cité, 75015 Paris, France; INSERM, U993, 75015 Paris, France., Sart S; LadHyX, CNRS, Ecole Polytechnique, Institut Polytechnique de Paris, 91120 Palaiseau, France; Physical Microfluidics and Bioengineering Unit, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France., Loe-Mie Y; Nuclear Organization and Oncogenesis Unit, Department of Cell Biology and Infection, Equipe Labellisée Ligue Nationale Contre le Cancer, Institut Pasteur, Université Paris Cité, 75015 Paris, France; INSERM, U993, 75015 Paris, France; Institut Pasteur, Université Paris Cité, Bioinformatics and Biostatistics HUB, 75015 Paris, France., Guthmann M; Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, 81377 München, Germany., Hendriks IA; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Theurillat I; Nuclear Organization and Oncogenesis Unit, Department of Cell Biology and Infection, Equipe Labellisée Ligue Nationale Contre le Cancer, Institut Pasteur, Université Paris Cité, 75015 Paris, France; INSERM, U993, 75015 Paris, France; Sorbonne Université, Collège Doctoral, 75005 Paris, France., Nielsen ML; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Torres-Padilla ME; Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, 81377 München, Germany; Faculty of Biology, Ludwig-Maximilians-Universität, 81377 München, Germany., Baroud CN; LadHyX, CNRS, Ecole Polytechnique, Institut Polytechnique de Paris, 91120 Palaiseau, France; Physical Microfluidics and Bioengineering Unit, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France., Dejean A; Nuclear Organization and Oncogenesis Unit, Department of Cell Biology and Infection, Equipe Labellisée Ligue Nationale Contre le Cancer, Institut Pasteur, Université Paris Cité, 75015 Paris, France; INSERM, U993, 75015 Paris, France. Electronic address: anne.dejean@pasteur.fr.

Publikováno v: Cell reports [Cell Rep] 2023 Apr 25; Vol. 42 (4), pp. 112380. Date of Electronic Publication: 2023 Apr 15.

Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer’s disease patients

Autor: Charles Duyckaerts, Malaplate-Armand C, Olivier Jl, Marie-Claude Potier, Isabelle Rivals, Marie Sarazin, Michel Bottlaender, Lorraine Hamelin, Hélène Corne, Julien Lagarde, Luce Dauphinot, Bruno Dubois, Kunie Ando, Guillaume Dorothée, G. Fontaine, Cossec Jc, Fabian Corlier

Publikováno v: Translational Psychiatry
Translational Psychiatry, Nature Pub. Group, 2015, 5 (7), pp.e595. ⟨10.1038/tp.2015.87⟩
Translational Psychiatry, 2015, 5 (7), pp.e595. ⟨10.1038/tp.2015.87⟩
Translational Psychiatry, 5
Translational Psychiatry, 2015, 5 (7), pp.e595. 〈10.1038/tp.2015.87〉

Identification of blood-based biomarkers of Alzheimer's disease (AD) remains a challenge. Neuropathological studies have identified enlarged endosomes in post-mortem brains as the earliest cellular change associated to AD. Here the presence of enlarg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e87d2340d30ac12e7f69c244a45325
https://hal.sorbonne-universite.fr/hal-01264449/document

Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome.

Autor: Botté A; Paris Brain Institute (ICM), CNRS UMR7225, INSERM U1127, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France., Lainé J; Paris Brain Institute (ICM), CNRS UMR7225, INSERM U1127, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France.; Sorbonne Université, Département de Physiologie, Hôpital de la Pitié-Salpêtrière, Paris, France., Xicota L; Paris Brain Institute (ICM), CNRS UMR7225, INSERM U1127, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France., Heiligenstein X; CryoCapCell, 155 Bd de l'hôpital, 75013, Paris, France.; Institut Curie, PSL Research University, CNRS, UMR144, Structure and Membrane Compartments, Paris, France., Fontaine G; Paris Brain Institute (ICM), CNRS UMR7225, INSERM U1127, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France., Kasri A; Paris Brain Institute (ICM), CNRS UMR7225, INSERM U1127, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France., Rivals I; Equipe de Statistique Appliquée, ESPCI Paris, PSL Research University, UMRS 1158, Paris, France., Goh P; The Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK., Faklaris O; ImagoSeine Imaging Core Facility, Institut Jacques Monod, CNRS UMR7592, Université Paris-Diderot, Sorbonne Paris Cité, Paris, France., Cossec JC; Paris Brain Institute (ICM), CNRS UMR7225, INSERM U1127, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France., Morel E; Institut Necker-Enfants Malades (INEM), INSERM U1151 CNRS UMR 8253, Université Paris Descartes-Sorbonne Paris Cité, Paris, France., Rebillat AS; Institut Jérôme Lejeune, Paris, France., Nizetic D; The Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Raposo G; Institut Curie, PSL Research University, CNRS, UMR144, Structure and Membrane Compartments, Paris, France., Potier MC; Paris Brain Institute (ICM), CNRS UMR7225, INSERM U1127, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France. marie-claude.potier@upmc.fr.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2020 Jun 24; Vol. 8 (1), pp. 89. Date of Electronic Publication: 2020 Jun 24.

Targeting SUMOylation with an injectable nanocomposite hydrogel to optimize radiofrequency ablation therapy for hepatocellular carcinoma.

Autor: Liu, Junfeng^1,2,3,4 (AUTHOR), Li, Xi^1,2,4 (AUTHOR) lixi57@mail.sysu.edu.cn, Chen, Jiawen^1,2,3,4 (AUTHOR), Guo, Jingpei^1,2,3,4 (AUTHOR), Guo, Hui^1,2,4 (AUTHOR), Zhang, Xiaoting^1,2,3,4 (AUTHOR), Fan, Jinming^1,2,3,4 (AUTHOR), Zhang, Ke^1,2,3,4 (AUTHOR), Mao, Junjie^1,2,4 (AUTHOR) maojunj@mail.sysu.edu.cn, Zhou, Bin^1,2,3,4 (AUTHOR) zhoub2@mail.sysu.edu.cn

Publikováno v: Journal of Nanobiotechnology. 7/11/2024, Vol. 22 Issue 1, p1-20. 20p.

SUMO-dependent transcriptional repression by Sox2 inhibits the proliferation of neural stem cells.

Autor: Marelli, Elisa¹ (AUTHOR) eli.marelli@gmail.com, Hughes, Jaime¹ (AUTHOR), Scotting, Paul J.¹ (AUTHOR)

Publikováno v: PLoS ONE. 3/20/2024, Vol. 19 Issue 3, p1-24. 24p.