Chromosomal instability increases radiation sensitivity.

Autor: Cosper PF; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Paracha M; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA., Jones KM; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA., Hrycyniak L; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, WI 53705, USA., Henderson L; Wisconsin State Laboratory of Hygiene, University of Wisconsin, Madison, WI., Bryan A; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA., Eyzaguirre D; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA., McCunn E; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA., Boulanger E; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA., Wan J; Physiology Graduate Training Program, University of Wisconsin-Madison, Madison, WI 53705, USA., Nickel KP; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA., Horner V; Wisconsin State Laboratory of Hygiene, University of Wisconsin, Madison, WI., Hu R; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI., Harari PM; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Kimple RJ; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705, USA.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Weaver BA; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53705, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 19. Date of Electronic Publication: 2024 Sep 19.

Human Papillomavirus-Induced Chromosomal Instability and Aneuploidy in Squamous Cell Cancers.

Autor: Mallick S; Department of Pathology and Cell Biology at the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.; Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, NY 10032, USA., Choi Y; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Cancer Biology Graduate Program, University of Wisconsin-Madison, Madison, WI 53705, USA., Taylor AM; Department of Pathology and Cell Biology at the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA., Cosper PF; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Carbone Cancer Center, University of Wisconsin, Madison, WI 53705, USA.

Publikováno v: Viruses [Viruses] 2024 Mar 25; Vol. 16 (4). Date of Electronic Publication: 2024 Mar 25.

HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E.

Autor: Cosper PF; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705., Hrycyniak LCF; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin-Madison, Madison, WI 53705., Paracha M; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705., Lee DL; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53705., Wan J; Physiology Graduate Training Program, University of Wisconsin-Madison, Madison, WI 53705., Jones K; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705., Bice SA; University of Wisconsin School of Medicine and Public Health, Madison, WI 53705., Nickel K; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705., Mallick S; Department of Pathology and Cell Biology at the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032.; Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, NY 10032., Taylor AM; Department of Pathology and Cell Biology at the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032., Kimple RJ; Department of Human Oncology, University of Wisconsin-Madison, Madison, WI 53705.; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705., Lambert PF; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705.; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53705., Weaver BA; University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705.; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53705.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Apr 04; Vol. 120 (14), pp. e2216700120. Date of Electronic Publication: 2023 Mar 29.

Why De-Intensification is not Possible in HPV-Associated Cervical Cancer.

Autor: Beaty BT; Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC., Cosper PF; University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, Madison, WI., Beriwal S; Department of Radiation Oncology, University of Pittsburgh Hillman Cancer Center, Pittsburgh, PA., Weiner AA; Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC. Electronic address: ashley_weiner@med.unc.edu.

Publikováno v: Seminars in radiation oncology [Semin Radiat Oncol] 2021 Oct; Vol. 31 (4), pp. 339-348.

Reply to A. J. Cmelak et al and B. Kalra et al.

Autor: Chundury A; Anupama Chundury, MD, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ; Pippa F. Cosper, MD, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI; and Sung Kim, MD, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ., Cosper PF; Anupama Chundury, MD, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ; Pippa F. Cosper, MD, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI; and Sung Kim, MD, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ., Kim S; Anupama Chundury, MD, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ; Pippa F. Cosper, MD, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI; and Sung Kim, MD, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2021 Aug 20; Vol. 39 (24), pp. 2735-2736. Date of Electronic Publication: 2021 May 27.