Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Cosmo D. del Vescovo"'
Publikováno v:
Cellular Signalling. 27:1984-1993
Cardiac hypertrophy is a complex remodeling process of the heart induced by physiological or pathological stimuli resulting in increased cardiomyocyte size and myocardial mass. Whereas cardiac hypertrophy can be an adaptive mechanism to stressful con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd231a68bbee14b99943b7b516352e4
https://doi.org/10.1016/j.cellsig.2015.06.009
https://doi.org/10.1016/j.cellsig.2015.06.009
Autor:
Cynthia Gonano, Erica Reggi, Francesco Raimondi, Michael Overduin, Francesca Fanelli, Clare L. Box, Elisa Dreyer, Dario Diviani, Halima Osman, Lucia Ruggieri, Michele Seeber, Sabrina Cavin, Luca Bellucci, Cosmo D. del Vescovo, Marc Lenoir
Publikováno v:
Cell chemical biology. 23(9)
Uncontrolled activation of Rho signaling by RhoGEFs, in particular AKAP13 (Lbc) and its close homologs, isimplicated in a number of human tumors with poor prognosis and resistance to therapy. Structure predictions and alanine scanning mutagenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549ff5674a5e257302c0deabc6014a26
https://pubmed.ncbi.nlm.nih.gov/27593112
https://pubmed.ncbi.nlm.nih.gov/27593112
Publikováno v:
Molecular and cellular biology. 33(1)
In response to stress, the heart undergoes a pathological remodeling process associated with hypertrophy and the reexpression of a fetal gene program that ultimately causes cardiac dysfunction and heart failure. In this study, we show that A-kinase-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d299136f64336e6653c88e4d09bda8b8
https://pubmed.ncbi.nlm.nih.gov/23149943
https://pubmed.ncbi.nlm.nih.gov/23149943
Publikováno v:
Biochimica et biophysica acta. 1833(4)
In response to stress or injury the heart undergoes a pathological remodeling process, associated with hypertrophy, cardiomyocyte death and fibrosis, that ultimately causes cardiac dysfunction and heart failure. It has become increasingly clear that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1afddcb2c019b4a58496592400dc93
https://pubmed.ncbi.nlm.nih.gov/22889610
https://pubmed.ncbi.nlm.nih.gov/22889610