Current Status and Future Directions in Graft-Versus-Host Disease Prevention Following Allogeneic Blood and Marrow Transplantation in Adults

Autor: Cosmin Tegla, Jun Choi, Maher Abdul-Hay, Frank Cirrone, Kelli Cole, A Samer Al-Homsi

Publikováno v: Clinical Hematology International, Vol 2, Iss 1 (2020)

Graft-versus-host disease (GvHD) in its acute and chronic forms continues to represent a significant barrier to the success and wide-applicability of blood and marrow transplantation as a potentially curative treatment modality for a number of benign

Externí odkaz: https://doaj.org/article/e90c6db1884a43ae9b938e53c702b24c

RGC-32 regulates reactive astrocytosis and extracellular matrix deposition in experimental autoimmune encephalomyelitis

Autor: Vinh Nguyen, Dallas Boodhoo, Horea Rus, Cornelia Cudrici, Anamaria Talpos-Caia, Armugam P. Mekala, Alexandru Tatomir, Cosmin Tegla, Tudor C. Badea, Freidrich Anselmo, Adam Sugarman, Violeta Rus, Alvaro Martin

Publikováno v: Immunologic Research. 66:445-461

Extracellular matrix (ECM) deposition in active demyelinating multiple sclerosis (MS) lesions may impede axonal regeneration and can modify immune reactions. Response gene to complement (RGC)-32 plays an important role in the mediation of TGF-β down

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498427a477dea4ca1d7da9daa701e3f5
https://doi.org/10.1007/s12026-018-9011-x

SIRT1 as a potential biomarker of response to treatment with glatiramer acetate in multiple sclerosis

Autor: Adam M. Kruszewski, Horea Rus, Gautam G. Rao, Walter Royal, Daniel Hewes, Jonathan Ciriello, Cosmin Tegla, Violeta Rus, Christopher T. Bever, Alexandru Tatomir, Vingh Nguyen

Publikováno v: Experimental and Molecular Pathology. 102:191-197

SIRT1, a NAD dependent histone and protein deacetylase, is a member of the histone deacetylase class III family. We previously showed that SIRT1 mRNA expression is significantly lower in peripheral blood mononuclear cells (PBMCs) of multiple sclerosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f96a46e46afe51d4b76495090942ae
https://doi.org/10.1016/j.yexmp.2017.01.014

STAT3 Dysregulation in Mature T and NK Cell Lymphomas

Autor: Sergei B. Koralov, Angelina Seffens, Kenneth B. Hymes, Cosmin Tegla, Terkild B. Buus, Alberto Herrera, Niels Ødum, Larisa J. Geskin

Publikováno v: Cancers
Cancers, Vol 11, Iss 11, p 1711 (2019)
Seffens, A, Herrera, A, Tegla, C, Buus, T B, Hymes, K B, Ødum, N, Geskin, L J & Koralov, S B 2019, ' STAT3 dysregulation in mature T and NK cell lymphomas ', Cancers, vol. 11, no. 11, 1711 . https://doi.org/10.3390/cancers11111711

T cell lymphomas comprise a distinct class of non-Hodgkin’s lymphomas, which include mature T and natural killer (NK) cell neoplasms. While each malignancy within this group is characterized by unique clinicopathologic features, dysregulation in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7a945c622e78268df1e01996f4e441
http://europepmc.org/articles/PMC6896161

Current Status and Future Directions in Graft-Versus-Host Disease Prevention Following Allogeneic Blood and Marrow Transplantation in Adults

Autor: Maher Abdul-Hay, A. Samer Al-Homsi, Cosmin Tegla, Frank Cirrone, Jun Choi, Kelli Cole

Publikováno v: Clinical Hematology International, Vol 2, Iss 1 (2020)

Graft-versus-host disease (GvHD) in its acute and chronic forms continues to represent a significant barrier to the success and wide-applicability of blood and marrow transplantation as a potentially curative treatment modality for a number of benign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a18b1a356847e6fe88614f186155d5a
https://doi.org/10.2991/chi.d.200115.001