Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Cosimo Cianfarini"'
Autor:
Cosimo Cianfarini, Luise Hassler, Jan Wysocki, Abdelsabour Hassan, Vlad Nicolaescu, Derek Elli, Haley Gula, Amany M. Ibrahim, Glenn Randall, Jack Henkin, Daniel Batlle
Publikováno v:
Cells, Vol 13, Iss 3, p 203 (2024)
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) utilizes angiotensin-converting enzyme 2 (ACE2) as its main receptor for cell entry. We bioengineered a soluble ACE2 protein termed ACE2 618-DDC-ABD that has increased binding to SARS-
Externí odkaz:
https://doaj.org/article/295ec820daf94cfd922ed4a4157279c9
Autor:
Luise Hassler, Jan Wysocki, Jared T. Ahrendsen, Minghao Ye, Ian Gelarden, Vlad Nicolaescu, Anastasia Tomatsidou, Haley Gula, Cosimo Cianfarini, Nigar Khurram, Yashpal Kanwar, Benjamin D. Singer, Glenn Randall, Dominique Missiakas, Jack Henkin, Daniel Batlle
Publikováno v:
bioRxiv
The present study was designed to investigate the effects of a soluble ACE2 protein termed ACE2 618-DDC-ABD, bioengineered to have long duration of action and high binding affinity to SARS-CoV-2, when administered either intranasally (IN) or intraper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5c7998fe70b3fdf23ff3ea51ceb838
https://europepmc.org/articles/PMC9753780/
https://europepmc.org/articles/PMC9753780/
Autor:
Luise Hassler, Jan Wysocki, Jared T Ahrendsen, Minghao Ye, Ian Gelarden, Vlad Nicolaescu, Anastasia Tomatsidou, Haley Gula, Cosimo Cianfarini, Peter Forster, Nigar Khurram, Benjamin D Singer, Glenn Randall, Dominique Missiakas, Jack Henkin, Daniel Batlle
Publikováno v:
Life Science Alliance. 6:e202301969
A soluble ACE2 protein bioengineered for long duration of action and high affinity to SARS-CoV-2 was administered either intranasally (IN) or intraperitoneally (IP) to SARS-CoV-2–inoculated k18hACE2 mice. This decoy protein (ACE2 618-DDC-ABD) was g