Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Cosima Quatraro"'
Autor:
I. D. Acu, Franca Stivala, Evanthia Galanis, Mark A. Schroeder, A B D'Assoro, M. M. Reinholz, Daniel J. Farrugia, Cosima Quatraro, Jeffrey L. Salisbury, Robert Busby, Cory Allen
Publikováno v:
Oncogene. 27:3901-3911
In this study, we establish an MCF-7 xenograft model that mimics the progression of human breast carcinomas typified by loss of p53 integrity, development of centrosome amplification, acquired estrogen receptor (ERalpha) heterogeneity, overexpression
Autor:
Cosima Quatraro, Wilma L. Lingle, Mateusz Opyrchal, Ianko D. Iankov, Yasuhiro Ikeda, Angela Amato, T Liu, James A. McCubrey, Vera J. Suman, A B D'Assoro, JN Ingle, Jeffrey Ecsedy, Amy C. Degnim, Daniel D. Billadeau, Seiga Ohmine, A Di Leonardo, J Ayers-Inglers, Alexey A. Leontovich, Evanthia Galanis, Jeffrey L. Salisbury
In this study, we demonstrate that constitutive activation of Raf-1 oncogenic signaling induces stabilization and accumulation of Aurora-A mitotic kinase that ultimately drives the transition from an epithelial to a highly invasive mesenchymal phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef5a4205e3c72d93a30bb3ea690a2cb
https://europepmc.org/articles/PMC4058768/
https://europepmc.org/articles/PMC4058768/
Autor:
Pierfrancesco Veroux, James N. Ingle, Cosima Quatraro, Ianko D. Iankov, Mario W. Gambino, Amy C. Degnim, Alexey A. Leontovich, James A. McCubrey, Evanthia Galanis, Shuya Zhang, Antonino B. D'Assoro
Aberrant activation of the Raf/MEK/MAPK pathway plays a key role in breast cancer development and progression. Dysregulation of Raf/MEK/MAPK oncogenic signaling often results from overexpression of the HER-2/Neu tyrosine kinase receptor leading to ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffddf7d7a43b53af97edae84e086440
http://hdl.handle.net/20.500.11769/48629
http://hdl.handle.net/20.500.11769/48629
Autor:
James N. Ingle, Kari A. Hafner, Jennifer R. Ayers-Ringler, Franca Stivala, Evanthia Galanis, Cosima Quatraro, Alexey A. Leontovich, Jeffrey L. Salisbury, Robert B. Jenkins, Massimo Libra, Angela Amato, Antonino B. D'Assoro
Publikováno v:
Europe PubMed Central
Development of chromosomal instability (CIN) and consequent phenotypic heterogeneity represent common events during breast cancer progression. Breast carcinomas harboring extensive chromosomal aberrations display a more aggressive behavior characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d4a01fd5709fa37c5957406fba9f31
http://hdl.handle.net/20.500.11769/44143
http://hdl.handle.net/20.500.11769/44143