Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Corrado Baglioni"'
Autor:
Corrado Baglioni, M. Gorospe
Publikováno v:
Journal of Biological Chemistry. 269:11845-11851
Labeled transcripts of interleukin-1 alpha (IL-1 alpha) cDNA were rapidly degraded in incubations with rabbit reticulocyte lysate (RRL). In contrast, a transcript of superoxide dismutase cDNA was stable in control incubations. A transcript of the 3'-
Publikováno v:
Experimental Gerontology. 28:505-513
Human diploid fibroblasts (HDFs) from newborn foreskin constitutively express interleukin-1 (IL-1) mRNA and protein after completing at least 70% (approximately 40 population doublings) of their in vitro life span. This IL-1 in turn induces the synth
Publikováno v:
Experimental Gerontology. 27:425-428
Publikováno v:
Proceedings of the National Academy of Sciences. 89:4683-4687
The interleukin 1 (IL-1)-inducible mRNAs for plasminogen activator inhibitor type 2, manganese superoxide dismutase, and urokinase are overexpressed in old (greater than 70% of life-span completed) but not in young (less than 40% of life-span complet
Publikováno v:
Journal of Biological Chemistry. 267:5257-5264
Porcine smooth muscle cells (SMC) grown to a high density monolayer culture undergo a morphological transition in which the cells draw away from the substrate and form multicellular nodules. The cells within the nodule resemble SMC in the aortic medi
Autor:
Corrado Baglioni, Juan Andres Melendez
Publikováno v:
Free Radical Biology and Medicine. 12:151-159
Tumor necrosis factor (TNF) induces synthesis of manganese superoxide dismutase (MnSOD). It was previously shown that overexpression of MnSOD protected some mammalian cells from TNF cytotoxicity. The purpose of this study was to establish whether MnS
Autor:
Sanjeev Kumar, Corrado Baglioni
Publikováno v:
Journal of Biological Chemistry. 266:20960-20964
Pretreatment of HT-1080 fibrosarcoma cells with tumor necrosis factor (TNF) induced resistance to the cytolytic activity of this cytokine in combination with cycloheximide. This resistance correlated with the synthesis of plasminogen activator inhibi
Autor:
K Peppel, Corrado Baglioni
Publikováno v:
Journal of Biological Chemistry. 266:6663-6666
The pathway of degradation of human interferon-beta (IFN-beta) mRNA was examined in murine C127 cells that carry an expression vector for this mRNA. The IFN-beta mRNA decayed with a half-life of approximately 45 min in actinomycin D-treated cells and
Publikováno v:
The Journal of Experimental Medicine
Different vectors were constructed that expressed the human interferon-beta (IFN-beta) mRNA constitutively and contained various deletions in the 3' untranslated region (UTR). AU-rich sequences in the 3' UTR were specifically deleted in two vectors.