Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Cornelia Liedtke"'
Autor:
Nadia Harbeck, Raquel von Schumann, Ronald Ernest Kates, Michael Braun, Sherko Kuemmel, Claudia Schumacher, Jochem Potenberg, Wolfram Malter, Doris Augustin, Bahriye Aktas, Helmut Forstbauer, Joke Tio, Eva-Maria Grischke, Claudia Biehl, Cornelia Liedtke, Sanne Lysbet De Haas, Regula Deurloo, Rachel Wuerstlein, Hans Heinrich Kreipe, Oleg Gluz
Publikováno v:
Cancers, Vol 13, Iss 19, p 4884 (2021)
Prognostic or predictive biomarkers in HER2-positive early breast cancer (EBC) may inform treatment optimization. The ADAPT HER2-positive/hormone receptor-positive phase II trial (NCT01779206) demonstrated pathological complete response (pCR) rates o
Externí odkaz:
https://doaj.org/article/3b01e2b99141444b9a656eaf4062dd12
Autor:
Thomas Karn, Lajos Pusztai, Uwe Holtrich, Takayuki Iwamoto, Christine Y Shiang, Marcus Schmidt, Volkmar Müller, Christine Solbach, Regine Gaetje, Lars Hanker, Andre Ahr, Cornelia Liedtke, Eugen Ruckhäberle, Manfred Kaufmann, Achim Rody
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28403 (2011)
BackgroundCurrent prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers. The identification of prognostic signatures from TNBC cohorts was limited in the past due to
Externí odkaz:
https://doaj.org/article/11e2ff571171401c9ba3fb6bd4809bd3
Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
Autor:
Lajos Pusztai, Vladimir Lazar, W. Fraser Symmans, Gabriel N. Hortobagyi, Suzette Delaloge, Gilles Vassal, Bailang Wang, Kai Yan, Catherine Richon, Cornelia Liedtke, Stefan Michiels, Attila Tordai, Philippe Dessen, Bastien Job, Fabrice Andre
Purpose: We used high-resolution oligonucleotide comparative genomic hybridization (CGH) arrays and matching gene expression array data to identify dysregulated genes and to classify breast cancers according to gene copy number anomalies.Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fdf9b58077bf877ad915b3bd17af7b
https://doi.org/10.1158/1078-0432.c.6517851
https://doi.org/10.1158/1078-0432.c.6517851
Autor:
Lajos Pusztai, Vladimir Lazar, W. Fraser Symmans, Gabriel N. Hortobagyi, Suzette Delaloge, Gilles Vassal, Bailang Wang, Kai Yan, Catherine Richon, Cornelia Liedtke, Stefan Michiels, Attila Tordai, Philippe Dessen, Bastien Job, Fabrice Andre
Supplementary Data from Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a452d2ce4a0e1ec5d09eaa9e5c727791
https://doi.org/10.1158/1078-0432.22440534
https://doi.org/10.1158/1078-0432.22440534
Autor:
Lajos Pusztai, W. Fraser Symmans, Gabriel N. Hortobagyi, Christos Hatzis, Feng Lin, Cornelia Liedtke, Kenneth R. Hess, Fei Huang, Kai Yan, Stacy Moulder
Patient selection is important for targeted therapies, yet phase I/II trials are often underpowered for developing predictors of drug response. The goal of this research was to define genomic predictors for dasatinib that could be prospectively teste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11509dbd7c7761091aa67f01cede9281
https://doi.org/10.1158/1535-7163.c.6531662
https://doi.org/10.1158/1535-7163.c.6531662
Autor:
Lajos Pusztai, W. Fraser Symmans, Gabriel N. Hortobagyi, Christos Hatzis, Feng Lin, Cornelia Liedtke, Kenneth R. Hess, Fei Huang, Kai Yan, Stacy Moulder
Supplementary Data from Development of Candidate Genomic Markers to Select Breast Cancer Patients for Dasatinib Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15328840ea90e00530bb4483058411b2
https://doi.org/10.1158/1535-7163.22484930
https://doi.org/10.1158/1535-7163.22484930
Autor:
Jayant S. Vaidya, H-C Kolberg, Samuele Massarut, E Whineray Kelly, György Lövey, Dennis R. Holmes, Cornelia Liedtke, Valery Uhl
Publikováno v:
Cancer Research. 79:P3-12
Background: Targeted intraoperative radiotherapy (TARGIT) has become a standard option during breast conserving surgery for selected cases of early breast cancer and over 20,000 patients have been treated in over 300 centers around the world. Althoug
Autor:
Dennis Görlich, Hans-Christian Kolberg, Tanja Fehm, L Kerschke, Ingo Bauerfeind, M. Hausschild, Gisela Helms, Lukas Schwentner, A Stäbler, Sabine Schmatloch, Gunter von Minckwitz, Michael Untch, Cornelia Liedtke, Thorsten Kühn, Annette Lebeau, Barbara Fleige, S. Loibl
Publikováno v:
Clinical & Experimental Metastasis. 35:777-783
Optimization of axillary staging among patients converting from clinically node-positive disease to clinically node-negative disease through primary systemic therapy is needed. We aimed at developing a nomogram predicting the probability of positive
Autor:
Cornelia Liedtke
Publikováno v:
gynäkologie + geburtshilfe. 23:32-36
Beim Mammakarzinom handelt es sich um eine sehr heterogene Erkrankung. Klinisch relevant sind vor allem Subgruppen, die durch die Expression zum Beispiel der Hormonrezeptoren definiert werden. Fur sie gibt es zielgerichtete Therapieansatze.