Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Cornelia, Donow"'
Autor:
Martin D. Burkhalter, Tom Stiff, Lars D. Maerz, Teresa Casar Tena, Heike Wiese, Julian Gerhards, Steffen A. Sailer, Linh Anna Trúc Vu, Max Duong Phu, Cornelia Donow, Marius Alupei, Sebastian Iben, Marco Groth, Sebastian Wiese, Joseph A. Church, Penelope A. Jeggo, Melanie Philipp
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)
Abstract The WD repeat-containing protein 4 (WDR4) has repeatedly been associated with primary microcephaly, a condition of impaired brain and skull growth. Often, faulty centrosomes cause microcephaly, yet aberrant cilia may also be involved. Here,
Externí odkaz:
https://doaj.org/article/c7c8e616bb0a44d686f248d5e16d846c
Autor:
Julian Gerhards, Lars D. Maerz, Edda S. F. Matthees, Cornelia Donow, Barbara Moepps, Richard T. Premont, Martin D. Burkhalter, Carsten Hoffmann, Melanie Philipp
Publikováno v:
Journal of the American Society of Nephrology. 34:590-606
Publikováno v:
Cancers, Vol 13, Iss 24, p 6220 (2021)
Ribosome biogenesis is essential for protein synthesis, cell growth and survival. The process takes places in nucleoli and is orchestrated by various proteins, among them RNA polymerases I–III as well as ribosome biogenesis factors. Perturbation of
Externí odkaz:
https://doaj.org/article/3fca0cd8e6874924a166850bd03f7f75
Autor:
Arthi Sridhar, Melanie Philipp, Susana S. Lopes, Stephanie M. Ware, Petra Pennekamp, Pedro Sampaio, Max Angenendt, Raquel Jacinto, Heymut Omran, Maja Hempel, Martina S. Burczyk, Paul Walther, Martin D. Burkhalter, Cornelia Donow
Publikováno v:
Journal of Clinical Investigation
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
J Clin Invest
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
J Clin Invest
About 1% of all newborns are affected by congenital heart disease (CHD). Recent findings identify aberrantly functioning cilia as a possible source for CHD. Faulty cilia also prevent the development of proper left-right asymmetry and cause heterotaxy
Vertical signalling involves transmission of Hox information from gastrula mesoderm to neurectoderm.
Autor:
Nabila Bardine, Gerda Lamers, Stephan Wacker, Cornelia Donow, Walter Knoechel, Antony Durston
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115208 (2014)
Development and patterning of neural tissue in the vertebrate embryo involves a set of molecules and processes whose relationships are not fully understood. Classical embryology revealed a remarkable phenomenon known as vertical signalling, a gastrul
Externí odkaz:
https://doaj.org/article/c12b436c21e74efb9f73b3968bb2203c
Autor:
Monika Kustermann, Svenja Laue, Yinghong Cui, Douglas G. Tilley, Laurel A. Grisanti, Melanie Rothe, Michael Kauk, Carsten Hoffmann, Melanie Philipp, WH Zimmermann, Teresa Casar Tena, Allessandra Moretti, Farah Raad, Michael Kühl, Martina S. Burczyk, Sabrina Matysik, Martin D. Burkhalter, Cornelia Donow, Jürgen Wess
Publikováno v:
JCI Insight
Deterioration or inborn malformations of the cardiac conduction system (CCS) interfere with proper impulse propagation in the heart and may lead to sudden cardiac death or heart failure. Patients afflicted with arrhythmia depend on antiarrhythmic med
Autor:
Julian Gerhards, Penny A. Jeggo, Lars D. Maerz, Cornelia Donow, Teresa Casar Tena, Melanie Philipp
Meier–Gorlin syndrome (MGS) is a rare, congenital primordial microcephalic dwarfism disorder. MGS is caused by genetic variants of components of the origin recognition complex (ORC) consisting of ORC1–6 and the pre-replication complex, which toge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fcbe815684518834c13b34d58a4914
Publikováno v:
Genesis (New York, N.Y. : 2000). 55(4)
The LIM-homeodomain transcription factor Tailup (Tup) is a component of the complex cardiac transcriptional network governing specification and differentiation of cardiac cells in Drosophila. LIM-domain containing factors are known to interact with t
FoxO genes are dispensable during gastrulation but required for late embryogenesis in Xenopus laevis
Autor:
Maximilian Schuff, Nabila Bardine, Cornelia Donow, Doreen Siegel, Franz Oswald, Walter Knöchel
Publikováno v:
Developmental Biology. 337(2):259-273
Forkhead box (Fox) transcription factors of subclass O are involved in cell survival, proliferation, apoptosis, cell metabolism and prevention of oxidative stress. FoxO genes are highly conserved throughout evolution and their functions were analyzed
Autor:
Walter Knöchel, Stephan A. Wacker, Nabila Bardine, Brigitte Korte, Cornelia Donow, Antony J. Durston
Publikováno v:
Developmental Dynamics. 238:755-765
Hox genes are key players in defining positional information along the main body axis of vertebrate embryos. In Xenopus laevis, Hoxc6 was the first homeobox gene isolated. It encodes two isoforms. We analyzed in detail their spatial and temporal expr