Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Corinne Maufrais"'
Autor:
Don N. Wickramasinghe, Claire M. Lyon, Sejeong Lee, Olivia W. Hepworth, Emily L. Priest, Corinne Maufrais, Adam P. Ryan, Emmanuelle Permal, Derek Sullivan, Brenda A. McManus, Bernhard Hube, Geraldine Butler, Christophe d'Enfert, Julian R. Naglik, Jonathan P. Richardson
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Candida albicans causes millions of mucosal infections in humans annually. Hyphal overgrowth on mucosal surfaces is frequently associated with tissue damage caused by candidalysin, a secreted peptide toxin that destabilizes the plasma membra
Externí odkaz:
https://doaj.org/article/3903d3d7c6d0456c8be1eb3b6dc95bad
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT At human body temperature, the fungal pathogen Candida albicans can transition from yeast to filamentous morphologies in response to host-relevant cues. Additionally, elevated temperatures encountered during febrile episodes can independentl
Externí odkaz:
https://doaj.org/article/747be2b79c0f4e14b1587775256cbb4a
Autor:
Thi Tuong Vi Dang, Corinne Maufrais, Jessie Colin, Frédérique Moyrand, Isabelle Mouyna, Jean-Yves Coppée, Chinaemerem U Onyishi, Joanna Lipecka, Ida Chiara Guerrera, Robin C May, Guilhem Janbon
Publikováno v:
PLoS Biology, Vol 22, Iss 7, p e3002724 (2024)
Alternative transcription start site (TSS) usage regulation has been identified as a major means of gene expression regulation in metazoans. However, in fungi, its impact remains elusive as its study has thus far been restricted to model yeasts. Here
Externí odkaz:
https://doaj.org/article/ea32ee1d318e4a9caf6b3fbe463daee5
Autor:
Laxmi Shanker Rai, Murielle Chauvel, Hiram Sanchez, Lasse van Wijlick, Corinne Maufrais, Thomas Cokelaer, Natacha Sertour, Mélanie Legrand, Kaustuv Sanyal, David R Andes, Sophie Bachellier-Bassi, Christophe d'Enfert
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002693 (2024)
Candida albicans is a commensal of the human microbiota that can form biofilms on implanted medical devices. These biofilms are tolerant to antifungals and to the host immune system. To identify novel genes modulating C. albicans biofilm formation, w
Externí odkaz:
https://doaj.org/article/950f30e96bf34aa18748985f1e9630d6
Autor:
Mayssa Gnaien, Corinne Maufrais, Yasmine Rebai, Aicha Kallel, Laurence Ma, Samia Hamouda, Fatma Khalsi, Khaoula Meftah, Hanen Smaoui, Monia Khemiri, Sondes Hadj Fredj, Sophie Bachellier-Bassi, Imène Najjar, Taieb Messaoud, Khadija Boussetta, Kalthoum Kallel, Helmi Mardassi, Christophe d'Enfert, Marie-Elisabeth Bougnoux, Sadri Znaidi
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012154 (2024)
Candida albicans chronically colonizes the respiratory tract of patients with Cystic Fibrosis (CF). It competes with CF-associated pathogens (e.g. Pseudomonas aeruginosa) and contributes to disease severity. We hypothesize that C. albicans undergoes
Externí odkaz:
https://doaj.org/article/3f782e6103b6485eb5a0f45c57ed332f
Autor:
Gabriela M. Avelar, Arnab Pradhan, Qinxi Ma, Emer Hickey, Ian Leaves, Corin Liddle, Alejandra V. Rodriguez Rondon, Ann-Kristin Kaune, Sophie Shaw, Corinne Maufrais, Natacha Sertour, Judith M. Bain, Daniel E. Larcombe, Leandro J. de Assis, Mihai G. Netea, Carol A. Munro, Delma S. Childers, Lars P. Erwig, Gordon D. Brown, Neil A. R. Gow, Marie-Elisabeth Bougnoux, Christophe d'Enfert, Alistair J. P. Brown
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Microbial species capable of co-existing with healthy individuals, such as the commensal fungus Candida albicans, exploit multifarious strategies to evade our immune defenses. These strategies include the masking of immunoinflammatory pathog
Externí odkaz:
https://doaj.org/article/a315d65d8db7474e9c59617b6af6132d
Autor:
Juliana Rizzo, Adèle Trottier, Frédérique Moyrand, Jean-Yves Coppée, Corinne Maufrais, Ana Claudia G. Zimbres, Thi Tuong Vi Dang, Alexandre Alanio, Marie Desnos-Ollivier, Isabelle Mouyna, Gérard Péhau-Arnaude, Pierre-Henri Commere, Sophie Novault, Iuliana V. Ene, Leonardo Nimrichter, Marcio L. Rodrigues, Guilhem Janbon
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Resistance to fluconazole (FLC), the most widely used antifungal drug, is typically achieved by altering the azole drug target and/or drug efflux pumps. Recent reports have suggested a link between vesicular trafficking and antifungal resist
Externí odkaz:
https://doaj.org/article/1274a0989de04827bef057b1db4905e4
Autor:
Priya Jaitly, Mélanie Legrand, Abhijit Das, Tejas Patel, Murielle Chauvel, Corinne Maufrais, Christophe d’Enfert, Kaustuv Sanyal
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Chromosomal instability caused by cell division errors is associated with antifungal drug resistance in fungal pathogens. Here, Jaitly et al. identify several genes involved in chromosomal stability in Candida albicans, including a phylogenetically r
Externí odkaz:
https://doaj.org/article/69779472c94d4e6d8bca92cea53fb545
Autor:
Selma Metaane, Véronique Monteil, Thibaut Douché, Quentin Giai Gianetto, Mariette Matondo, Corinne Maufrais, Françoise Norel
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291736 (2023)
In many Gram-negative bacteria, the stress sigma factor of RNA polymerase, σS/RpoS, remodels global gene expression to reshape the physiology of stationary phase cells and ensure their survival under non-optimal growth conditions. In the foodborne p
Externí odkaz:
https://doaj.org/article/d17db0965fe542e08a5bfec5677b9c11
Autor:
Jonathan P. Richardson, Rhys Brown, Nessim Kichik, Sejeong Lee, Emily Priest, Selene Mogavero, Corinne Maufrais, Don N. Wickramasinghe, Antzela Tsavou, Natalia K. Kotowicz, Olivia W. Hepworth, Ana Gallego-Cortés, Nicole O. Ponde, Jemima Ho, David L. Moyes, Duncan Wilson, Christophe D’Enfert, Bernhard Hube, Julian R. Naglik
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen. Candidalysin is secreted by Candida albicans and is critical for driving infection and host immune responses in several model systems. However, Candid
Externí odkaz:
https://doaj.org/article/7a4e9cd34a2f4184b02a7bf66ce31248