Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Corinne E. Griguer"'
Publikováno v:
Cell Stress, Vol 6, Iss 4, Pp 45-60 (2022)
Glioblastoma (GBM) is a fatal disease with recurrences often associated with radioresistance. Although often effective at treating newly diagnosed GBM, increasing evidence suggests that radiotherapy-induced alterations in tumor metabolism promote GBM
Externí odkaz:
https://doaj.org/article/8c00afdcd8c1420bbb9f2be14bd325be
Autor:
Amber B. Jones, Taylor L. Schanel, Mikayla R. Rigsby, Corinne E. Griguer, Braden C. McFarland, Joshua C. Anderson, Christopher D. Willey, Anita B. Hjelmeland
Publikováno v:
Cells, Vol 12, Iss 17, p 2171 (2023)
Treatment for the deadly brain tumor glioblastoma (GBM) has been improved through the non-invasive addition of alternating electric fields, called tumor treating fields (TTFields). Improving both progression-free and overall survival, TTFields are cu
Externí odkaz:
https://doaj.org/article/19c6825befad40668d16c836d7cbcc8d
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 349 (2023)
Median overall survival is very low in patients with glioblastoma (GBM), largely because these tumors become resistant to therapy. Recently, we found that a decrease in the cytosolic labile iron pool underlies the acquisition of radioresistance. Both
Externí odkaz:
https://doaj.org/article/38cd6d7a56464c7b847b993479868298
Publikováno v:
Cells, Vol 11, Iss 21, p 3464 (2022)
Iron is essential for many cellular processes, but cellular iron homeostasis must be maintained to ensure the balance of cellular signaling processes and prevent disease. Iron transport in and out of the cell and cellular organelles is crucial in thi
Externí odkaz:
https://doaj.org/article/c20f76f8dab04376bf94be96a6eff363
Publikováno v:
Metabolites, Vol 12, Iss 8, p 748 (2022)
Although often effective at treating newly diagnosed glioblastoma (GBM), increasing evidence suggests that chemo- and radiotherapy-induced alterations in tumor metabolism promote GBM recurrence and aggressiveness, as well as treatment resistance. Rec
Externí odkaz:
https://doaj.org/article/8bc07d1da2354a4f8eb659b36ef5dbcb
Autor:
Woong-Jai Won, Jessy S. Deshane, Jianmei W. Leavenworth, Claudia R. Oliva, Corinne E. Griguer
Publikováno v:
Cell Stress, Vol 3, Iss 2, Pp 48-65 (2019)
Glioblastoma, also known as glioblastoma multiforme, is the most common and deadliest form of high-grade malignant brain tumors with limited available treatments. Within the glioblastoma tumor microenvironment (TME), tumor cells, stromal cells, and i
Externí odkaz:
https://doaj.org/article/5d2bdb44a9da4b6ab59195b2e19d5420
Autor:
Yeni L. Bernal Rubio, Agustin González-Reymúndez, Kuan-Han H. Wu, Corinne E. Griguer, Juan P. Steibel, Gustavo de los Campos, Andrea Doseff, Kathleen Gallo, Ana I. Vazquez
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 11, Pp 3627-3636 (2018)
Glioblastoma multiforme (GBM) has been recognized as the most lethal type of malignant brain tumor. Despite efforts of the medical and research community, patients’ survival remains extremely low. Multi-omic profiles (including DNA sequence, methyl
Externí odkaz:
https://doaj.org/article/69289e9a1f4f4c9cbef95b675a37294a
IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling
Autor:
Claudia R. Oliva, Brian Halloran, Anita B. Hjelmeland, Ana Vazquez, Shannon M. Bailey, Jann N. Sarkaria, Corinne E. Griguer
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background Glioblastomas (GBMs), the most common and most lethal of the primary brain tumors, are characterized by marked intra-tumor heterogeneity. Several studies have suggested that within these tumors a restricted population of chemoresi
Externí odkaz:
https://doaj.org/article/eaac1cb954844514889bc70083825e78
Autor:
Rajesh Kumar Gandhirajan, Katrin Rödder, Yana Bodnar, Gabriella Pasqual-Melo, Steffen Emmert, Corinne E. Griguer, Klaus-Dieter Weltmann, Sander Bekeschus
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Despite striking advances in the treatment of metastasized melanoma, the disease is often still fatal. Attention is therefore paid towards combinational regimens. Oxidants endogenously produced in mitochondria are currently targeted in pre-c
Externí odkaz:
https://doaj.org/article/e7765252a4bf4fd98c1c2fb12bede776
Autor:
Susanne Flor, Claudia R. Oliva, Md Yousuf Ali, Kristen L. Coleman, Jeremy D. Greenlee, Karra A. Jones, Varun Monga, Corinne E. Griguer
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1988 (2021)
Glioblastoma remains the deadliest form of brain cancer, largely because these tumors become resistant to standard of care treatment with radiation and chemotherapy. Intracellular production of reactive oxygen species (ROS) is necessary for chemo- an
Externí odkaz:
https://doaj.org/article/e470bfc0424d4aeaa02e4939e1e2ef87