Behavioural and psychological symptoms of dementia in Down syndrome: Early indicators of clinical Alzheimer's disease?

Autor: Dekker AD; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium. Electronic address: a.d.dekker@umcg.nl., Strydom A; Division of Psychiatry, University College London, London, United Kingdom. Electronic address: a.strydom@ucl.ac.uk., Coppus AM; Department for Primary and Community Care, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Tonnie.Coppus@radboudumc.nl., Nizetic D; The Blizard Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. Electronic address: d.nizetic@qmul.ac.uk., Vermeiren Y; Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium. Electronic address: yannick.vermeiren@uantwerpen.be., Naudé PJ; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: p.j.w.naude@umcg.nl., Van Dam D; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium. Electronic address: debby.vandam@uantwerpen.be., Potier MC; Sorbonne Universités, UPMC Univ Paris 06, Inserm, CNRS, UM 75, U 1127, UMR 7225, ICM, Paris, France. Electronic address: marie-claude.potier@upmc.fr., Fortea J; Catalan Down Syndrome Foundation and Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. Electronic address: jfortea@santpau.cat., De Deyn PP; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium. Electronic address: p.p.de.deyn@umcg.nl.

Publikováno v: Cortex; a journal devoted to the study of the nervous system and behavior [Cortex] 2015 Dec; Vol. 73, pp. 36-61. Date of Electronic Publication: 2015 Aug 13.

Serum MHPG strongly predicts conversion to Alzheimer's disease in behaviorally characterized subjects with Down syndrome.

Autor: Dekker AD; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium., Coppus AM; Dichterbij, Center for the Intellectually Disabled, Gennep, The Netherlands Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, The Netherlands., Vermeiren Y; Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium., Aerts T; Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Kremer BP; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Naudé PJ; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Van Dam D; Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium., De Deyn PP; Department of Neurology and Alzheimer Research Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium.

Publikováno v: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2015; Vol. 43 (3), pp. 871-91.

People with intellectual disability: what do we know about adulthood and life expectancy?

Autor: Coppus AM; Dichterbij, Center for the Intellectually Disabled, Medical Center, Gennep, The Netherlands. t.coppus@elg.umcn.nl

Publikováno v: Developmental disabilities research reviews [Dev Disabil Res Rev] 2013; Vol. 18 (1), pp. 6-16.

Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome.

Autor: Coppus AM; Dichterbij, Center for the Intellectually Disabled, Gennep, The Netherlands. a.coppus@erasmusmc.nl, Schuur M, Vergeer J, Janssens AC, Oostra BA, Verbeek MM, van Duijn CM

Publikováno v: Neurobiology of aging [Neurobiol Aging] 2012 Sep; Vol. 33 (9), pp. 1988-94. Date of Electronic Publication: 2011 Sep 29.

Early age at menopause is associated with increased risk of dementia and mortality in women with Down syndrome.

Autor: Coppus AM; Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, The Netherlands Dichterbij, Centre for the Intellectually Disabled, Gennep, The Netherlands., Evenhuis HM, Verberne GJ, Visser FE, Eikelenboom P, van Gool WA, Janssens AC, van Duijn CM

Publikováno v: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2010; Vol. 19 (2), pp. 545-50.