The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

Autor: Romano B 1, Borrelli F 1, Fasolino I 1, Capasso R 1, Piscitelli F 3, Cascio M 4, Pertwee R 4, Coppola D 5, Vassallo L 5, Orlando P 6, Di Marzo V 3, Izzo A 1

Publikováno v: British journal of pharmacology (Online) 169 (2013): 213–229. doi:10.1111/bph.12120
info:cnr-pdr/source/autori:Romano B 1, Borrelli F 1, Fasolino I 1, Capasso R 1, Piscitelli F 3, Cascio M 4, Pertwee R 4, Coppola D 5, Vassallo L 5, Orlando P 6, Di Marzo V 3, Izzo A 1/titolo:The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis./doi:10.1111%2Fbph.12120/rivista:British journal of pharmacology (Online)/anno:2013/pagina_da:213/pagina_a:229/intervallo_pagine:213–229/volume:169

The non-psychotropic cannabinoid cannabichromene is known to activate the transient receptor potential ankyrin-type1 (TRPA1) and to inhibit endocannabinoid inactivation, both of which are involved in inflammatory processes. We examined here the effec

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http://hdl.handle.net/11588/563904