Zobrazeno 1 - 10
of 1 124
pro vyhledávání: '"Copper-64"'
Autor:
Catarina I. G. Pinto, André D. M. Branco, Sara Bucar, Alexandra Fonseca, Antero J. Abrunhosa, Cláudia L. da Silva, Joana F. Guerreiro, Filipa Mendes
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background Glioblastoma is an extremely aggressive malignant tumor with a very poor prognosis. Due to the increased proliferation rate of glioblastoma, there is the development of hypoxic regions, characterized by an increased concentration
Externí odkaz:
https://doaj.org/article/fb07ff3d769046bc8ef6dbf895b15980
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-24 (2024)
Abstract Background Programmed cell death ligand 1 (PD-L1) plays a critical role in the tumor microenvironment and overexpression in several solid cancers has been reported. This was associated with a downregulation of the local immune response, spec
Externí odkaz:
https://doaj.org/article/6b92fb27767c475693a3d55f22417df7
Publikováno v:
مجله علوم و فنون هستهای, Vol 44, Iss 4, Pp 67-75 (2023)
Calculating the absorbed dose in the human body is one of the first steps in radiopharmaceutical development. This study estimates the dose absorbed by humans from the novel identified compound of 64Cu-NODAGA-RGD-BBN. For this purpose, 64Cu-NODAGA-RG
Externí odkaz:
https://doaj.org/article/bb41afcd5f2a41629db14595332fcb9c
Autor:
Silvano Gnesin, Nicolas Chouin, Michel Cherel, Steven Mark Dunn, Niklaus Schaefer, Alain Faivre-Chauvet, John O. Prior, Judith Anna Delage
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The development of diagnostic and therapeutic radiopharmaceuticals is an hot topic in nuclear medicine. Several radiolabeled antibodies are under development necessitating both biokinetic and dosimetry extrapolations for effective human tran
Externí odkaz:
https://doaj.org/article/675c9d24f452478b9c0e94b40b313ada
Autor:
Bianca Gutfilen, Adriano Duatti
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/5531ae8716e24392974213ba7c7eefbb
Autor:
Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Ivanna Hrynchak, Roxana Tudoroiu-Cornoiu, Sergio J. C. do Carmo, Bogdan Burghelea, Simona Băruță, Ana Rita Almeida, Radu Șerban, Anca Dinischiotu, Antero J. Abrunhosa, Dana Niculae
Publikováno v:
Molecules, Vol 29, Iss 6, p 1390 (2024)
On the verge of a theranostic approach to personalised medicine, copper-64 is one of the emerging radioisotopes in nuclear medicine due to its exploitable nuclear and biochemical characteristics. The increased demand for copper-64 for preclinical and
Externí odkaz:
https://doaj.org/article/65aa69a591734cd7a2fe00914b4c8230
Autor:
Hwa Yeon Jeong, Seong Jae Kang, Min Woo Kim, In-ho Jeong, Moon Jung Choi, Cheulhee Jung, In Ho Song, Tae Sup Lee, Yong Serk Park
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1813 (2024)
Combining standard surgical procedures with personalized chemotherapy and the continuous monitoring of cancer progression is necessary for effective NSCLC treatment. In this study, we developed liposomal nanoparticles as theranostic agents capable of
Externí odkaz:
https://doaj.org/article/2d219f25a7204d93b9af81abf548d4af
Autor:
Jhonatan Carrasco-Hernandez, José Ramos-Méndez, Elizabeth Padilla-Rodal, Miguel A. Avila-Rodriguez
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
PurposeTargeted Radionuclide Therapy (TRT) with Auger Emitters (AE) is a technique that allows targeting specific sites on tumor cells using radionuclides. The toxicity of AE is critically dependent on its proximity to the DNA. The aim of this study
Externí odkaz:
https://doaj.org/article/1e70d9bb68844643b34b7c333dcd2c4a
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
Radionuclides are of paramount importance in nuclear medicine both for clinical uses and radiopharmaceutical production. Among the others, nuclides suitable for theranostics like Copper-64 are particularly attractive since they can play both a diagno
Externí odkaz:
https://doaj.org/article/b74db2780a1040fc8e1b1c5051b31724
Autor:
Radu M. Serban, Dana Niculae, Gina Manda, Ionela Neagoe, Maria Dobre, Dragoș A. Niculae, Mihaela Temelie, Cosmin Mustăciosu, Radu A. Leonte, Livia E. Chilug, Maria R. Cornoiu, Diana Cocioabă, Miruna Stan, Anca Dinischiotu
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Due to combined therapeutical emissions, a high linear energy transfer Auger-electrons with the longer ranged β− particles, 64Cu-based radiopharmaceuticals raise particular theragnostic interest in cancer, by joined therapeutic and real-time PET i
Externí odkaz:
https://doaj.org/article/352b7750a7bd41189e42c3e244ffa060