Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Copper chelator"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116874- (2024)
Copper, an indispensable micronutrient, is implicated in numerous vital biological processes and is essential for all physiological activities. Recently, the discovery of a novel type of copper-dependent cell death, known as cuproptosis, has shed lig
Externí odkaz:
https://doaj.org/article/1355a711543a443aae06e2657022bf20
Autor:
Kihoon Nam, Harim Tavares Dos Santos, Frank M. Maslow, Travis Small, Vinit Shanbhag, Michael J. Petris, Olga J. Baker
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24368- (2024)
Radiation therapy is a first-line treatment for head and neck cancer; however, it typically leads to hyposalivation stemming from fibrosis of the salivary gland. Current strategies to restore glandular function are dependent on the presence of residu
Externí odkaz:
https://doaj.org/article/43719b19c2094d53b60256dd4ef040b3
Autor:
Ioan-Cristian Lupescu, Maria Speranta Iacob, Razvan Iacob, Daniela Anghel, Octavia Adriana Dulamea, Crisanda Vilciu, Liliana Gheorghe
Publikováno v:
Romanian Journal of Neurology, Vol 22, Iss 1, Pp 23-29 (2023)
Background. Wilson disease (WD) is an autosomal-recessive disorder of copper metabolism, caused by mutations in the ATP7B gene, which codes for a membrane-bound copper-binding ATPase. This leads to progressive copper accumulation in the liver, with h
Externí odkaz:
https://doaj.org/article/f282d3dea9b54dc19a1025262ace537c
Autor:
Ngoc Kim Nguyen, Bella Poduska, Mia Franks, Manoranjan Bera, Ian MacCormack, Guoxing Lin, Alexander P. Petroff, Samir Das, Arundhati Nag
Publikováno v:
Biosensors, Vol 14, Iss 5, p 247 (2024)
Copper is an essential trace metal for biological processes in humans and animals. A low level of copper detection at physiological pH using fluorescent probes is very important for in vitro applications, such as the detection of copper in water or u
Externí odkaz:
https://doaj.org/article/e50e3f7ef255457d82aeb165d289c7f4
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2719 (2023)
(1) Background: In patients with Wilson’s disease, the deficiency of the copper carrier ATP7B causes the accumulation of copper in the liver, brain and various other organs. Lifelong treatment is therefore mandatory, using copper chelators to incre
Externí odkaz:
https://doaj.org/article/efb43be0c3e54af1aa8ad9506abb7e20
Akademický článek
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Autor:
Lan Huang, Yaoxun Zeng, Yongliang Li, Yingshan Zhu, Yan He, Yan Liu, Anne Robert, Bernard Meunier
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2691 (2022)
(1) Background: TDMQ20 is a specific regulator of copper homeostasis in the brain, able to inhibit cognitive impairment in the early stages of Alzheimer’s disease (AD) in mouse models of AD. To promote the further development of this drug-candidate
Externí odkaz:
https://doaj.org/article/134c603b490b40a4b6e1430a63f47637
Akademický článek
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Autor:
Giulia Tamburini, Carmen Canevali, Silvia Ferrario, Alberto Bianchi, Antonio Sansonetti, Roberto Simonutti
Publikováno v:
Materials, Vol 15, Iss 19, p 6739 (2022)
The synthesis of hydrogels that are based on poly-hydroxyethyl methacrylate, p(HEMA), network semi-interpenetrated with linear polyvinylpyrrolidone (PVP) was optimized in order to allow both a fast preparation and a high cleaning effectiveness of art
Externí odkaz:
https://doaj.org/article/f615e22eaaf84cc488546f6edbd649dd
Akademický článek
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