Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain.

Autor: Culshaw AJ; Novartis Institutes for Biomedical Research, London WC1E 6BS, UK. andrew.culshaw@novartis.com, Bevan S, Christiansen M, Copp P, Davis A, Davis C, Dyson A, Dziadulewicz EK, Edwards L, Eggelte H, Fox A, Gentry C, Groarke A, Hallett A, Hart TW, Hughes GA, Knights S, Kotsonis P, Lee W, Lyothier I, McBryde A, McIntyre P, Paloumbis G, Panesar M, Patel S, Seiler MP, Yaqoob M, Zimmermann K

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2006 Jan 26; Vol. 49 (2), pp. 471-4.