Ribaxamase, an Orally Administered β-Lactamase, Diminishes Changes to Acquired Antimicrobial Resistance of the Gut Resistome in Patients Treated with Ceftriaxone

Autor: Kokai-Kun JF, Le C, Trout K, Cope JL, Ajami NJ, Degar AJ, Connelly S

Publikováno v: Infection and Drug Resistance, Vol Volume 13, Pp 2521-2535 (2020)

John F Kokai-Kun,1 Chenxiong Le,1 Kenneth Trout,1 Julia L Cope,2 Nadim J Ajami,2 Andrew J Degar,2 Sheila Connelly1 1Synthetic Biologics, Inc., Rockville, MD, USA; 2Diversigen, Inc., Houston, TX, USACorrespondence: Sheila Connelly Email sconnelly@synt

Externí odkaz: https://doaj.org/article/93c8890c7d314fa5bd992fa13a7a6cc7

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Exploring disease-causing traits for drug repurposing in critically ill COVID-19 patients: A causal inference approach.

Autor: Baukmann HA; biotx.ai GmbH, Am Mühlenberg 11, 14476 Potsdam, Germany., Cope JL; biotx.ai GmbH, Am Mühlenberg 11, 14476 Potsdam, Germany., Bannard C; University of Manchester, Oxford Road, Manchester M13 9PL, UK., Schwinges AREC; biotx.ai GmbH, Am Mühlenberg 11, 14476 Potsdam, Germany., Lamparter MRJ; biotx.ai GmbH, Am Mühlenberg 11, 14476 Potsdam, Germany., Groves S; School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol BS8 1DT, UK., Ravarani CNJ; biotx.ai GmbH, Am Mühlenberg 11, 14476 Potsdam, Germany., Amulic B; School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol BS8 1DT, UK., Klinger JE; biotx.ai GmbH, Am Mühlenberg 11, 14476 Potsdam, Germany., Schmidt MF; biotx.ai GmbH, Am Mühlenberg 11, 14476 Potsdam, Germany.

Publikováno v: IScience [iScience] 2023 Oct 12; Vol. 26 (11), pp. 108185. Date of Electronic Publication: 2023 Oct 12 (Print Publication: 2023).

Leveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome.

Autor: Hollister EB; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Diversigen, Inc., Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Oezguen N; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Chumpitazi BP; Department of Pediatrics, Baylor College of Medicine, Houston, Texas; Section of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Texas Children's Hospital, Houston, Texas., Luna RA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Weidler EM; Department of Pediatrics, Baylor College of Medicine, Houston, Texas; Section of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Texas Children's Hospital, Houston, Texas; Children's Nutrition Research Center, Houston, Texas., Rubio-Gonzales M; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Dahdouli M; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Cope JL; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Mistretta TA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Raza S; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Metcalf GA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas., Muzny DM; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas., Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas., Petrosino JF; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas., Heitkemper M; Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, Washington., Savidge TC; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas., Shulman RJ; Department of Pediatrics, Baylor College of Medicine, Houston, Texas; Section of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Texas Children's Hospital, Houston, Texas; Children's Nutrition Research Center, Houston, Texas., Versalovic J; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; Texas Children's Microbiome Center, Texas Children's Hospital, Houston, Texas; Department of Pathology, Texas Children's Hospital, Houston, Texas; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas. Electronic address: jamesv@bcm.edu.

Publikováno v: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2019 May; Vol. 21 (3), pp. 449-461. Date of Electronic Publication: 2019 Apr 17.