Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Cooper, Patricia A."'
Autor:
Pitto-Barry, Anaïs, Azmanova, Maria, Rafols, Laia, Cooper, Patricia A., Seaton, Colin C., Shnyder, Steven
Yes
The synthesis, characterisation, and evaluation of the in vitro cytotoxicity of five maleonitriledithiolate-based ruthenium metal complexes bearing various phosphine ligands towards two ovarian cancer cell lines (A2780 and A2780cisR), one no
The synthesis, characterisation, and evaluation of the in vitro cytotoxicity of five maleonitriledithiolate-based ruthenium metal complexes bearing various phosphine ligands towards two ovarian cancer cell lines (A2780 and A2780cisR), one no
Externí odkaz:
http://hdl.handle.net/10454/19068
Autor:
Ashton, M.D., Cooper, Patricia A., Municoy, S., Desimone, M.F., Cheneler, D., Shnyder, Steven, Hardy, J.G.
Yes
Biomaterials capable of precisely controlling the delivery of agrochemicals/biologics/drugs/fragrances have significant markets in the agriscience/healthcare industries. Here, we report the development of degradable electroactive polymers an
Biomaterials capable of precisely controlling the delivery of agrochemicals/biologics/drugs/fragrances have significant markets in the agriscience/healthcare industries. Here, we report the development of degradable electroactive polymers an
Externí odkaz:
http://hdl.handle.net/10454/19067
Autor:
Presa, Daniela, Khurram, S.A., Zubir, A.Z.A., Swaroop, Sneha, Cooper, Patricia A., Morais, Goreti R., Sadiq, Maria, Sutherland, Mark, Loadman, Paul, McCaul, Jim, Shnyder, Steven, Patterson, Laurence H., Pors, Klaus
Yes
Epidemiological studies have shown that head and neck cancer (HNC) is a complex multistage process that in part involves exposure to a combination of carcinogens and the capacity of certain drug-metabolising enzymes including cytochrome P450
Epidemiological studies have shown that head and neck cancer (HNC) is a complex multistage process that in part involves exposure to a combination of carcinogens and the capacity of certain drug-metabolising enzymes including cytochrome P450
Externí odkaz:
http://hdl.handle.net/10454/19728
Autor:
Soldevila-Barreda, Joan J., Azmanova, Maria, Pitto-Barry, Anaïs, Cooper, Patricia A., Shnyder, Steven, Barry, Nicolas P.E.
Yes
Ruthenium compounds have been shown to be promising alternatives to platinum(II) drugs. However, their clinical success depends on achieving mechanisms of action that overcome Pt-resistance mechanisms. Electron-deficient organoruthenium comp
Ruthenium compounds have been shown to be promising alternatives to platinum(II) drugs. However, their clinical success depends on achieving mechanisms of action that overcome Pt-resistance mechanisms. Electron-deficient organoruthenium comp
Externí odkaz:
http://hdl.handle.net/10454/18025
Autor:
Ahmet, Djevdet S., Basheer, H.A., Salem, Anwar, Lu, Di, Aghamohammadi, Amin, Weyerhäuser, P., Bordiga, A., Almeniawi, J., Rashid, S., Cooper, Patricia A., Shnyder, Steven, Vinader, Victoria, Afarinkia, Kamyar
Yes
The formylpeptide receptor-1 (FPR1) is a member of the chemotactic GPCR-7TM formyl peptide receptor family, whose principle function is in trafficking of various leukocytes into sites of bacterial infection and inflammation. More recently, F
The formylpeptide receptor-1 (FPR1) is a member of the chemotactic GPCR-7TM formyl peptide receptor family, whose principle function is in trafficking of various leukocytes into sites of bacterial infection and inflammation. More recently, F
Externí odkaz:
http://hdl.handle.net/10454/18145
Autor:
Basheer, Haneen A., Pakanavicius, E., Cooper, Patricia A., Shnyder, Steven, Martin, L., Hunter, K.D., Vinader, Victoria, Afarinkia, Kamyar
Yes
The chemokine receptor CCR7 is expressed on lymphocytes and dendritic cells and is responsible for trafficking of these cells in and out of secondary lymphoid organs. It has recently been shown that CCR7 expression is elevated in a number of
The chemokine receptor CCR7 is expressed on lymphocytes and dendritic cells and is responsible for trafficking of these cells in and out of secondary lymphoid organs. It has recently been shown that CCR7 expression is elevated in a number of
Externí odkaz:
http://hdl.handle.net/10454/15563
Autor:
Allison, Simon J., Sadiq, Maria, Baronou, Efstathia, Cooper, Patricia A., Dunnill, C., Georgopoulos, N.T., Latif, A., Shepherd, S.L., Shnyder, Steven, Stratford, I.J., Wheelhouse, Richard T., Willans, C., Phillips, Roger M.
Yes
Organometallic complexes offer the prospect of targeting multiple pathways that are important in cancer biology. Here, the preclinical activity and mechanism(s) of action of a silver-bis(N-heterocyclic carbine) complex (Ag8) were evaluated.
Organometallic complexes offer the prospect of targeting multiple pathways that are important in cancer biology. Here, the preclinical activity and mechanism(s) of action of a silver-bis(N-heterocyclic carbine) complex (Ag8) were evaluated.
Externí odkaz:
http://hdl.handle.net/10454/11960
Autor:
O'Flaherty, L., Shnyder, Steven, Cooper, Patricia A., Cross, S.J., Wakefield, J.G., Pardo, O.E., Seckl, M.J., Tavare, J.M.
Yes
Glycogen synthase kinase-3 (GSK3) is over-expressed and hyperactivated in non-small cell lung carcinoma (NSCLC) and plays a role in ensuring the correct alignment of chromosomes on the metaphase plate during mitosis through regulation of mic
Glycogen synthase kinase-3 (GSK3) is over-expressed and hyperactivated in non-small cell lung carcinoma (NSCLC) and plays a role in ensuring the correct alignment of chromosomes on the metaphase plate during mitosis through regulation of mic
Externí odkaz:
http://hdl.handle.net/10454/17021
Autor:
Hussain, Nosheen, Cooper, Patricia A., Shnyder, Steven, Ugail, Hassan, Bukar, Ali M., Connah, David
As part of the cancer drug development process, evaluation in experimental subcutaneous tumour transplantation models is a key process. This involves implanting tumour material underneath the mouse skin and measuring tumour growth using calipers. Thi
Externí odkaz:
http://hdl.handle.net/10454/14543
Autor:
Hussain, Nosheen, Connah, David, Ugail, Hassan, Cooper, Patricia A., Falconer, Robert A., Patterson, Laurence H., Shnyder, Steven
Yes
Non-invasive methods to monitor tumour growth are an important goal in cancer drug development. Thermographic imaging systems offer potential in this area, since a change in temperature is known to be induced due to changes within the tumour
Non-invasive methods to monitor tumour growth are an important goal in cancer drug development. Thermographic imaging systems offer potential in this area, since a change in temperature is known to be induced due to changes within the tumour
Externí odkaz:
http://hdl.handle.net/10454/8781