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pro vyhledávání: '"Cooper, Curt S."'
Aviation security: biometric technology and risk based security aviation passenger screening program
Autor:
Cooper, Curt S.
CHDS State/Local
Since 9/11, the Transportation Security Administration (TSA) has struggled to maintain a balance between providing a secure world-class aviation passenger-screening program (APSP) while providing efficiency, convenience and secu
Since 9/11, the Transportation Security Administration (TSA) has struggled to maintain a balance between providing a secure world-class aviation passenger-screening program (APSP) while providing efficiency, convenience and secu
Externí odkaz:
http://hdl.handle.net/10945/27811
Autor:
Tianyuan Zhang, Richard A. G. Smith, Rohinton Edalji, Yu-Gui Gu, John L. Baranowski, William J. Sanders, Bruce A. Beutel, Liping Yu, Philip J. Hajduk, Annapur Gurulingappa Shivakumar, Stephan J. Kakavas, Frank L. Wagenaar, Darlene J. Balli, Steven F. Betz, Richard F. Clark, Kenneth M. Comess, Eric J. Hebert, J. Owen McCall, Jamey Mack, Linda E. Chovan, Randy E. Metzger, Thomas F. Holzman, Anne Y. Saiki, Sarah A. Dorwin, Niru B. Soni, Mai Bui, Angela M. Nilius, Susan J. Thornewell, Cooper Curt S, Mark E. Schurdak, Michael L. Coen, Rolf Wagner, Alan S. Florjancic, Philip J. Merta, Claude G. Lerner, Charlotte Woodall, Candace Black-Schaefer, John E. Harlan, Mengli Cai, Karl A. Walter, Xenia B. Searle, Stephen W. Fesik
Publikováno v:
Chemical Biology & Drug Design. 69:395-404
As part of a fully integrated and comprehensive strategy to discover novel antibacterial agents, NMR- and mass spectrometry-based affinity selection screens were performed to identify compounds that bind to protein targets uniquely found in bacteria
Autor:
J. Owen McCall, Bruce A. Beutel, Philip J. Hajduk, Geoffrey F. Stamper, Richard F. Clark, Yingna Cia, Kenton L. Longenecker, Elizabeth H. Fry, Candace Black-Schaefer, Clarissa G. Jakob, Cooper Curt S, Alan S. Florjancic, Claude G. Lerner, Vincent S. Stoll, Yu-Gui Gu, David D. Anderson, Tianyuan Zhang
Publikováno v:
Chemical biologydrug design. 67(1)
The D-Ala-D-Ala adding enzyme (MurF) from Streptococcus pneumoniae catalyzes the ATP-dependent formation of the UDP-MurNAc-pentapeptide, a critical component of the bacterial cell wall. MurF is a potential target for antibacterial design because it i
Autor:
J. Owen McCall, Claude G. Lerner, Tianyuan Zhang, Cooper Curt S, Richard F. Clark, Geoffrey F. Stamper, Yingna Cai, Candace Black-Schaefer, David D. Anderson, Philip J. Hajduk, Yu Gui Gu, Alan S. Florjancic, Bruce A. Beutel
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(1)
A novel class of MurF inhibitors was discovered and structure-activity relationship studies have led to several potent compounds with IC(50)=22 approximately 70 nM. Unfortunately, none of these potent MurF inhibitors exhibited significant antibacteri
Autor:
Linus L. Shen, Angela M. Nilius, Yat Sun Or, Qun Li, Sanyi Wang, Anthony K. L. Fung, Robert K. Flamm, Zhenkun Ma, Jeffery D. Alder, Cooper Curt S, Jonathan A. Meulbroek, Daniel T. W. Chu
Publikováno v:
Journal of medicinal chemistry. 42(20)
The antibacterial 4H-4-oxoquinolizines were introduced recently to overcome bacterial resistance to fluoroquinolones. They exhibit potent antibacterial activity against Gram-positive, Gram-negative, and anaerobic organisms and are highly active again
Akademický článek
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Autor:
Gu, Yu Gui, Florjancic, Alan S., Clark, Richard F., Zhang, Tianyuan, Cooper, Curt S., Anderson, David D., Lerner, Claude G., McCall, J.Owen, Cai, Yingna, Black-Schaefer, Candace L., Stamper, Geoffrey F., Hajduk, Philip J., Beutel, Bruce A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2004 14(1):267-270
Autor:
Stamper, Geoffrey F., Longenecker, Kenton L., Fry, Elizabeth H., Jakob, Clarissa G., Florjancic, Alan S., Yu-Gui Gu, Anderson, David D., Cooper, Curt S., Tianyuan Zhang, Clark, Richard F., Cia, Yingna, Black-Schaefer, Candace L., Owen McCall, J., Lerner, Claude G., Hajduk, Philip J., Beutel, Bruce A., Stoll, Vincent S.
Publikováno v:
Chemical Biology & Drug Design; Jan2006, Vol. 67 Issue 1, p58-65, 8p, 6 Color Photographs, 6 Diagrams
Autor:
Snyder, Ronald D., Cooper, Curt S.
Publikováno v:
Photochemistry & Photobiology; Mar1999, Vol. 69 Issue 3, p288-293, 6p
Autor:
Cooper, Curt S., Weinkam, Robert J.
Publikováno v:
Journal of Labelled Compounds & Radiopharmaceuticals; Oct1984, Vol. 21 Issue 10, p925-936, 12p