Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor

Autor: Chinthalapally V, Rao, Cooma, Indranie, Barbara, Simi, Pamela T, Manning, Jane R, Connor, Bandaru S, Reddy

Publikováno v: Cancer research. 62(1)

The inducible isoforms of nitric oxide synthase (iNOS) and cyclooxygenase (COX-2) are overexpressed in colonic tumors of humans, as well as in colon tumors that develop in rats after the administration of the colon-specific carcinogen, azoxymethane (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8faaae6c8edf472470ee03f8e5be156
https://pubmed.ncbi.nlm.nih.gov/11782374

Chemoprevention of Colon Carcinogenesis by Oleanolic Acid and Its Analog in Male F344 Rats and Modulation of COX-2 and Apoptosis in Human Colon HT-29 Cancer Cells.

Autor: Naveena Janakiram, Cooma Indranie, Swamy Malisetty, Patlolla Jagan, Vernon Steele

Publikováno v: Pharmaceutical Research; Sep2008, Vol. 25 Issue 9, p2151-2157, 7p

Chemoprevention of familial adenomatous polyposis development in the APCmin mouse model by 1,4-phenylene bis(methylene)selenocyanate.

Autor: Rao, Chinthalapally V., Cooma, Indranie, Rodriguez, Jose G.Rosa, Simi, Barbara, El-Bayoumy, Karam, Reddy, Bandaru S.

Publikováno v: Carcinogenesis; Apr2000, Vol. 21 Issue 4, p617-621, 5p

Modulation of cyclooxygenase-2 activities by the combined action of celecoxib and decosahexaenoic acid: novel strategies for colon cancer prevention and treatment.

Autor: Swamy MV; Chemoprevention and Nutritional Carcinogenesis Program, Institute for Cancer Prevention, American Health Foundation-Cancer Center, Valhalla, NY, USA., Cooma I, Patlolla JM, Simi B, Reddy BS, Rao CV

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2004 Feb; Vol. 3 (2), pp. 215-21.