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pro vyhledávání: '"Cookson Mark R"'
Autor:
Kuhn Alexandre, Kumar Azad, Beilina Alexandra, Dillman Allissa, Cookson Mark R, Singleton Andrew B
Publikováno v:
BMC Genomics, Vol 13, Iss 1, p 610 (2012)
Abstract Background Interpreting gene expression profiles obtained from heterogeneous samples can be difficult because bulk gene expression measures are not resolved to individual cell populations. We have recently devised Population-Specific Express
Externí odkaz:
https://doaj.org/article/8d02b72cd48c4c69a25df3d4e720b64e
Autor:
Reilly, Luke, Lara, Erika, Ramos, Daniel, Li, Ziyi, Pantazis, Caroline B., Stadler, Julia, Santiana, Marianita, Roberts, Jessica, Faghri, Faraz, Hao, Ying, Nalls, Mike A., Narayan, Priyanka, Liu, Yansheng, Singleton, Andrew B., Cookson, Mark R., Ward, Michael E., Qi, Yue A.
Publikováno v:
In Cell Reports Methods 23 October 2023 3(10)
Akademický článek
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Akademický článek
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Publikováno v:
BMC Medicine, Vol 10, Iss 1, p 20 (2012)
Abstract Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are a common cause of familial Parkinson's disease (PD). Variation around the LRRK2 locus also contributes to the risk of sporadic PD. The LRRK2 protein contains a central catalytic
Externí odkaz:
https://doaj.org/article/2de0830ab5e144e1977cf20bf598af9b
Publikováno v:
BMC Neuroscience, Vol 11, Iss 1, p 41 (2010)
Abstract Background Oxidative stress has been proposed to be involved in the pathogenesis of Parkinson's disease (PD). A plausible source of oxidative stress in nigral dopaminergic neurons is the redox reactions that specifically involve dopamine and
Externí odkaz:
https://doaj.org/article/023626302c3d493ab12b348db3d89271
Autor:
Cookson Mark R
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 9 (2009)
Abstract α-Synuclein is a small protein that has special relevance for understanding Parkinson disease and related disorders. Not only is α-synuclein found in Lewy bodies characteristic of Parkinson disease, but also mutations in the gene for α-sy
Externí odkaz:
https://doaj.org/article/a4b7cdf5302e484bb9b4e038cc76f045
Autor:
Rogaeva Ekaterina, Hutton Michael L, Adamson Jennifer, Wassermann Eric M, Huey Edward D, Holtzman David M, Fung Hon, Chiò Adriano, Pickering-Brown Stuart, Berger Stephen, Greenway Matthew J, Greggio Elisa, Cairns Nigel J, Cookson Mark R, Jain Shushant, Schymick Jennifer, Momeni Parastoo, St George-Hyslop Peter, Rothstein Jeffrey D, Hardiman Orla, Grafman Jordan, Singleton Andrew, Hardy John, Traynor Bryan J
Publikováno v:
BMC Neurology, Vol 6, Iss 1, p 44 (2006)
Abstract Background A new locus for amyotrophic lateral sclerosis – frontotemporal dementia (ALS-FTD) has recently been ascribed to chromosome 9p. Methods We identified chromosome 9p segregating haplotypes within two families with ALS-FTD (F476 and
Externí odkaz:
https://doaj.org/article/ddfa16b0fe0040538ac1b5136221f70f
Autor:
Dadu, Anant, Satone, Vipul K., Kaur, Rachneet, Koretsky, Mathew J., Iwaki, Hirotaka, Qi, Yue A., Ramos, Daniel M., Avants, Brian, Hesterman, Jacob, Gunn, Roger, Cookson, Mark R., Ward, Michael E., Singleton, Andrew B., Campbell, Roy H., Nalls, Mike A., Faghri, Faraz
Publikováno v:
In Patterns 9 June 2023 4(6)
Autor:
Cookson Mark R, Bandyopadhyay Sourav
Publikováno v:
BMC Evolutionary Biology, Vol 4, Iss 1, p 6 (2004)
Abstract Background Inferences about protein function are often made based on sequence homology to other gene products of known activities. This approach is valuable for small families of conserved proteins but can be difficult to apply to large supe
Externí odkaz:
https://doaj.org/article/4320262d61964ee3aeb88fb47eac7f17