Zobrazeno 1 - 10 of 237 pro vyhledávání: '"Cookson, WO"'
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Role of airway glucose in bacterial infections in chronic obstructive pulmonary disease
Autor: Tregoning, JS, Mallia, P, Webber, J, Gill, SK, Trujillo-Torralbo, Calderazzo, MA, Finney, L, Bakhsoliani, E, Farne, H, Singanayagam, A, Footitt, J, Hewitt, R, Kebadze, Aniscenko, J, Padmanaban, V, Molyneaux, PL, Adcock, Barnes, PJ, Ito, K, Elkin, SL, Kon, OM, Cookson, WO, MOffatt, MF, Johnston, SL
Publikováno v: 823.e6
Background Patients with chronic obstructive pulmonary disease (COPD) have increased susceptibility to respiratory tract infection, which contributes to disease progression and mortality, but mechanisms of increased susceptibility to infection remain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::7cacca7b75319ee598561c063cf76b24
http://hdl.handle.net/10044/1/55776
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4
A 2.8 Mb YAC contig in 11q12-q13 localizes candidate genes for atopy: Fc epsilon RI beta and CD20
Autor: Stafford, AN, Rider, SH, Hopkin, JM, Cookson, WO, Monaco, AP
An important locus for Atopy (familial asthma, hay fever and eczema) has been localized to the 11q12-q13 region with the minimum recombination fraction around the CD20 gene. We have constructed a 2.8 megabase (Mb) Yeast Artificial Chromosome (YAC) co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2cf66d9018baa42c52b3beb9667ebeff
https://ora.ox.ac.uk/objects/uuid:470f0bdb-e185-47f8-94af-dff4292e17ea
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6
Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant
Autor: Zhang, Y, Dean, C, Chessum, L, Dao, N, Stewart, M, Taylor, M, Cookson, WO, Moffatt, MF
Publikováno v: Zhang, Y, Dean, C, Chessum, L, Nguyen, D, Stewart, M, Taylor, M, Cookson, W O & Moffatt, M F 2014, ' Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant ', Mammalian Genome, vol. 25, no. 11-12 . https://doi.org/10.1007/s00335-014-9535-x
Previously, human genetic studies have shown association between polymorphisms within the gene encoding plant homeodomain zinc finger protein 11 (PHF11) and asthma-related phenotypes. Initial functional studies have suggested that PHF11 may be involv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::02ef2deb4dbc10cfa2db99a1315d0286
https://www.pure.ed.ac.uk/ws/files/17910121/Functional_analysis_of_a_novel_ENU_induced_PHD_finger_11_Phf11_mouse_mutant.pdf
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7
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
Autor: Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard Costa NL, Hottenga JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges Armstrong LM, Alcohol Genome wide Association Consortium, Diabetes Genetics Replication, Meta analyses Study, Genetic Investigation of Anthropometric Traits Consortium, Global Lipids Genetics Consortium, Genetics of Liver Disease Consortium, International Consortium for Blood Pressure, Meta analyses of Glucose, Insulin Related Traits Consortium, Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietiläinen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala Korpela M, Stefansson K, Vollenweider P, Völzke H, Schadt EE, Scott J, Järvelin MR, Elliott P, Kooner JS, PAOLISSO, Giuseppe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3977::a4185907badefbf6ea0e2a83bdb3dec0
http://hdl.handle.net/11591/204402
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IFITM3 restricts the morbidity and mortality associated with influenza
Autor: Everitt, AR, Clare, S, Pertel, T, John, SP, Wash, RS, Smith, SE, Chin, CR, Feeley, EM, Sims, JS, Adams, DJ, Wise, HM, Kane, L, Goulding, D, Digard, P, Anttila, V, Baillie, JK, Walsh, TS, Hume, DA, Palotie, A, Xue, Y, Colonna, V, Tyler-Smith, C, Dunning, J, Gordon, SB, Everingham, K, Dawson, H, Hope, D, Ramsay, P, Walsh Local Lead Investigator, TS, Campbell, A, Kerr, S, Harrison, D, Rowan, K, Addison, J, Donald, N, Galt, S, Noble, D, Taylor, J, Webster Local Lead Investigator, N, Taylor Local Lead Investigator, I, Aldridge Local Lead Investigator, J, Dornan, R, Richard, C, Gilmour, D, Simmons Local Lead Investigator, R, White Local Lead Investigator, R, Jardine, C, Williams Local Lead Investigator, D, Booth Local Lead Investigator, M, Quasim, T, Watson, V, Henry, P, Munro, F, Bell, L, Ruddy Local Lead Investigator, J, Cole Local Lead Investigator, S, Southward, J, Allcoat, P, Gray, S, McDougall Local Lead Investigator, M, Matheson, J, Whiteside Local Lead Investigator, J, Alcorn, D, Rooney Local Lead Investigator, K, Sundaram, R, Imrie Local Lead Investigator, G, Bruce, J, McGuigan, K, Moultrie Local Lead Investigator, S, Cairns Local Lead Investigator, C, Grant, J, Hughes, M, Murdoch Local Lead Investigator, C, Davidson Local Lead Investigator, A, Harris, G, Paterson, R, Wallis Local Lead Investigator, C, Binning Local Lead Investigator, S, Pollock, M, Antonelli, J, Duncan, A, Gibson, J, McCulloch, C, Murphy, L, Haley, C, Faulkner, G, Freeman, T, Baillie Principal Investigator, JK, Chaussabel, D, Adamson, WE, Carman, WF, Thompson, C, Zambon, MC, Aylin, P, Ashby, D, Barclay, WS, Brett, SJ, Cookson, WO, Drumright, LN, Elderfield, RA, Garcia-Alvarez, L, Gazzard, BG, Griffiths, MJ, Habibi, MS, Hansel, TT, Herberg, JA, Holmes, AH, Hussell, T, Johnston, SL, Kon, OM, Levin, M, Moffatt, MF, Nadel, S, Openshaw, PJ, Warner, JO, Aston, SJ, Hay, A, McCauley, J, O'Garra, A, Banchereau, J, Hayward, A, Kellam, P, Simmonds, P, McNamara, PS, Semple, MG, Smyth, RL, Nguyen-Van-Tam, JS, Ho, L-P, Mcmichael, AJ, Dougan, G, Brass, AL
Publikováno v: Nature.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::fcace3f3eee5e522e3016725260088aa
http://ora.ox.ac.uk/objects/uuid:5767640c-b018-4ac1-8a06-9bc95843b505
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9
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
Autor: Chambers, JC, Zhang, W, Sehmi, J, Li, X, Wass, MN, Van der Harst, P, Holm, H, Sanna, S, Kavousi, M, Baumeister, SE, Coin, LJ, Deng, G, Gieger, C, Heard-Costa, NL, Hottenga, J-J, Kühnel, B, Kumar, V, Lagou, V, Liang, L, Luan, J, Vidal, PM, Leach, IM, O'Reilly, PF, Peden, JF, Rahmioglu, N, Soininen, P, Speliotes, EK, Yuan, X, Thorleifsson, G, Alizadeh, BZ, Atwood, LD, Borecki, IB, Brown, MJ, Charoen, P, Cucca, F, Das, D, de Geus, EJC, Dixon, AL, Döring, A, Ehret, G, Eyjolfsson, GI, Farrall, M, Forouhi, NG, Friedrich, N, Goessling, W, Gudbjartsson, DF, Harris, TB, Hartikainen, A-L, Heath, S, Hirschfield, GM, Hofman, A, Homuth, G, Hyppönen, E, Janssen, HLA, Johnson, T, Kangas, AJ, Kema, IP, Kühn, JP, Lai, S, Lathrop, M, Lerch, MM, Li, Y, Liang, TJ, Lin, J-P, Loos, RJF, Martin, NG, Moffatt, MF, Montgomery, GW, Munroe, PB, Musunuru, K, Nakamura, Y, O'Donnell, CJ, Olafsson, I, Penninx, BW, Pouta, A, Prins, BP, Prokopenko, I, Puls, R, Ruokonen, A, Savolainen, MJ, Schlessinger, D, Schouten, JNL, Seedorf, U, Sen-Chowdhry, S, Siminovitch, KA, Smit, JH, Spector, TD, Tan, W, Teslovich, TM, Tukiainen, T, Uitterlinden, AG, Van der Klauw, MM, Vasan, RS, Wallace, C, Wallaschofski, H, Wichmann, H-E, Willemsen, G, Würtz, P, Xu, C, Yerges-Armstrong, LM, Abecasis, GR, Ahmadi, KR, Boomsma, DI, Caulfield, M, Cookson, WO, van Duijn, CM, Froguel, P, Matsuda, K, McCarthy, MI, Meisinger, C, Mooser, V, Pietiläinen, KH, Schumann, G, Snieder, H, Sternberg, MJE, Stolk, RP, Thomas, HC, Thorsteinsdottir, U, Uda, M, Waeber, G, Wareham, NJ, Waterworth, DM, Watkins, H, Whitfield, JB, Witteman, JCM, Wolffenbuttel, BHR, Fox, CS, Ala-Korpela, M, Stefansson, K, Vollenweider, P, Völzke, H, Schadt, EE, Scott, J, Järvelin, M-R, Elliott, P, Kooner, JS
Publikováno v: Nature Genetics.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::369ce9b41b9088842b95167e9b559d68
http://ora.ox.ac.uk/objects/uuid:042bdd82-393a-4bd1-a5c5-c8815e9725d4
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10
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