Succinct Data Structures for Assembling Large Genomes

Autor: Conway, Thomas C, Bromage, Andrew J

Motivation: Second generation sequencing technology makes it feasible for many researches to obtain enough sequence reads to attempt the de novo assembly of higher eukaryotes (including mammals). De novo assembly not only provides a tool for understa

Externí odkaz: http://arxiv.org/abs/1008.2555

Short read sequence typing (SRST): multi-locus sequence types from short reads

Autor: Inouye Michael, Conway Thomas C, Zobel Justin, Holt Kathryn E

Publikováno v: BMC Genomics, Vol 13, Iss 1, p 338 (2012)

Abstract Background Multi-locus sequence typing (MLST) has become the gold standard for population analyses of bacterial pathogens. This method focuses on the sequences of a small number of loci (usually seven) to divide the population and is simple,

Externí odkaz: https://doaj.org/article/cc877d96499145afaf1e51fb1b28d695

WGS Analysis and Interpretation in Clinical and Public Health Microbiology Laboratories: What Are the Requirements and How Do Existing Tools Compare?

Autor: Wyres KL; IBM Research-Australia, Level 5, 204 Lygon Street, Carlton, Victoria 3206, Australia. kelwyres@au1.ibm.com., Conway TC; IBM Research-Australia, Level 5, 204 Lygon Street, Carlton, Victoria 3206, Australia. tconway@au1.ibm.com., Garg S; IBM Research-Australia, Level 5, 204 Lygon Street, Carlton, Victoria 3206, Australia. saurabh.kr.garg@gmail.com., Queiroz C; IBM Research-Australia, Level 5, 204 Lygon Street, Carlton, Victoria 3206, Australia. caxqueiroz@gmail.com., Reumann M; IBM Research-Zuerich, Säumerstrasse 4, Rüschlikon 8803, Switzerland. MRE@zurich.ibm.com., Holt K; Bio21 Institute, University of Melbourne, 30 Flemington Road, Melbourne, Parkville, VIC 3052, Australia. kholt@unimelb.edu.au., Rusu LI; IBM Research-Australia, Level 5, 204 Lygon Street, Carlton, Victoria 3206, Australia. laurusu@au1.ibm.com.

Publikováno v: Pathogens (Basel, Switzerland) [Pathogens] 2014 Jun 11; Vol. 3 (2), pp. 437-58. Date of Electronic Publication: 2014 Jun 11.