Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with Covid-19. A randomized clinical trial

Autor: Lawler, P.R., Derde, L.P.G., Veerdonk, F.L. van de, McVerry, B.J., Huang, D.T., Berry, L.R., Lorenzi, E., Kimmenade, R.R.J. van, Gommans, F., Vaduganathan, M., Leaf, D.E., Baron, R.M., Kim, E.Y., Frankfurter, C., Epelman, S., Kwan, Y., Grieve, R., O'Neill, S., Sadique, Z., Puskarich, M., Marshall, J.C., Higgins, A.M., Mouncey, P.R., Rowan, K.M., Al-Beidh, F., Annane, D., Arabi, Y.M., Au, C., Beane, A., Bentum-Puijk, W. van, Bonten, M.J.M., Bradbury, C.A., Brunkhorst, F.M., Burrell, A., Buzgau, A., Buxton, M., Cecconi, M., Cheng, A.C., Cove, M., Detry, M.A., Estcourt, L.J., Ezekowitz, J., Fitzgerald, M., Gattas, D., Godoy, L.C., Goossens, H., Haniffa, R., Harrison, D.A., Hills, T., Horvat, C.M., Ichihara, N., Lamontagne, F., Linstrum, K.M., McAuley, D.F., McGlothlin, A., McGuinness, S.P., McQuilten, Z., Murthy, S., Nichol, A.D., Owen, D.R.J., Parke, R.L., Parker, J.C., Pollock, K.M., Reyes, L.F., Saito, H., Santos, M.S., Saunders, C.T., Seymour, C.W., Shankar-Hari, M., Singh, V., Turgeon, A.F., Turner, A.M., Zarychanski, R., Green, C., Lewis, R.J., Angus, D.C., Berry, S., Gordon, A.C., McArthur, C.J., Webb, S.A.

Publikováno v: Lawler, P R, Derde, L P G, Van De Veerdonk, F L, McVerry, B J, Huang, D T, Berry, L R, Lorenzi, E, Van Kimmenade, R, Gommans, F, Vaduganathan, M, Leaf, D E, Baron, R M, Kim, E Y, Frankfurter, C, Epelmaņ, S, Kwan, Y, Grieve, R, O'Neill, S, Sadique, Z, Puskarich, M, Marshall, J C, Higgins, A M, Mouncey, P R, Rowan, K M, Al-Beidh, F, Annane, D, Arabi, Y M, Au, C, Beane, A, Van Bentum-Puijk, W, Bonten, M J M, Bradbury, C A, Brunkhorst, F M, Burrell, A, Buzgau, A, Buxton, M, Cecconi, M, Cheng, A C, Cove, M, Detry, M A, Estcourt, L J, Ezekowitz, J, Fitzgerald, M, Gattas, D, Godoy, L C, Goossens, H, Haniffa, R, Harrison, D A, Hills, T, Horvat, C M, Ichihara, N, Lamontagne, F, Linstrum, K M, McAuley, D F, McGlothlin, A, McGuinness, S P, McQuilten, Z, Murthy, S, Nichol, A D, Owen, D R J, Parke, R L, Parker, J C, Pollock, K M, Reyes, L F, Saito, H, Santos, M S, Saunders, C T, Seymour, C W, Shankar-Hari, M, Singh, V, Turgeon, A F, Turner, A M, Zarychanski, R, Green, C, Lewis, R J, Angus, D C, Berry, S, Gordon, A C, McArthur, C J & Webb, S A 2023, ' Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with Covid-19. A randomized clinical trial ', JAMA, vol. 329, no. 14, pp. 1183-1196 . https://doi.org/10.1001/jama.2023.4480
Jama : Journal of the American Medical Association, 329, 14, pp. 1183-1196
Jama : Journal of the American Medical Association, 329, 1183-1196

Contains fulltext : 291878.pdf (Publisher’s version ) (Closed access) IMPORTANCE: Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. OBJECTIVE: To determine whether angiotensin-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8ff6a211c4c42dc02259195c83981b0d
https://pure.qub.ac.uk/en/publications/8cae3556-8039-49ea-a414-6da1b5a01052

Feasibility and Association of Neurohumoral Blocker Up-titration After Cardiac Resynchronization Therapy

Autor: Frederik H. Verbrugge, Pieter Martens, Wilson W.H. Tang, Philippe Bertrand, Matthias Dupont, Petra Nijst, Wilfried Mullens

Publikováno v: Journal of Cardiac Failure. 23:597-605

Background Cardiac resynchronization therapy (CRT) improves mortality and morbidity on top of optimal medical therapy in heart failure with reduced ejection fraction (HFrEF). This study aimed to elucidate the association between neurohumoral blocker

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a175a1ccb130ee6c05392809f2cacd3e
https://doi.org/10.1016/j.cardfail.2017.03.001

Two novel peptides with angiotensin I converting enzyme inhibitory and antioxidative activities from Scorpaena notata muscle protein hydrolysate

Autor: Neyssene, Aissaoui, Ferid, Abidi, Julie, Hardouin, Zaineb, Abdelkafi, Naziha, Marrakchi, Thierry, Jouenne, M Nejib, Marzouki

Publikováno v: Biotechnology and Applied Biochemistry
Biotechnology and Applied Biochemistry, Wiley, 2017, 64 (2), pp.201-210. ⟨10.1002/bab.1478⟩

International audience; Fish protein hydrolysate was prepared from muscle of small red scorpionfish (Scorpaena notata) by treatment with a protease from the fungus Penicillium digitatum. Protein hydrolysate was found to strongly inhibit the angiotens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5fbf78aa10b5ed97ba240c88a64876fc
https://hal.archives-ouvertes.fr/hal-01539027

Intestinal Transport of the Lactokinin Ala-Leu-Pro-Met-His-Ile-Arg through a Caco-2 Bbe Monolayer

Autor: Vanessa Vermeirssen, H. R. Gaskins, Kelly A. Tappenden, Willy Verstraete, J. Van Camp, Bart Deplancke

Publikováno v: Journal of Peptide Science. 8:95-100

ACE inhibitory peptides are biologically active peptides that play a role in blood pressure regulation. When derived from food proteins during food processing or gastrointestinal digestion, these peptides could function as efficient agents in treatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09525f8695dff0ee267be94bfca454c
https://doi.org/10.1002/psc.371

Captopril-induced glutamate release at the start of reperfusion after cold cardioplegic storage of pig hearts

Autor: Ulla Møldrup, Thomas Bjerre, Torsten Toftegaard Nielsen, Hans-Henrik Kimose, Flemming Randsbæk, Hans Erik Bøtker

Publikováno v: Randsbaek, F, Kimose, H H, Bjerre, T, Moldrup, U, Botker, H E & Nielsen, T T 2000, ' Captopril-induced glutamate release at the start of reperfusion after cold cardioplegic storage of pig hearts ', The Journal of Thoracic and Cardiovascular Surgery, vol. 119, no. 5, pp. 1030-8 . https://doi.org/10.1016/S0022-5223(00)70099-7
Randsbaek, F, Kimose, H H, Bjerre, T, Moldrup, U, Botker, H E & Nielsen, T T 2000, ' Captopril-induced glutamate release at the start of reperfusion after cold cardioplegic storage of pig hearts ', The Journal of Thoracic and Cardiovascular Surgery, vol. 119, no. 5, pp. 1030-1038 . https://doi.org/10.1016/S0022-5223(00)70099-7
Scopus-Elsevier

Objective: We sought to evaluate the effects of captopril on glucose-related metabolism during hypothermic cardioplegic storage and subsequent reperfusion. Methods: We compared hearts from control pigs with hearts from pigs treated with increasing or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f12393e8edfc76a90428a29f22b192