Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease.

Autor: Spanos M; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Albert Einstein College of Medicine/ North Central Bronx/Jacobi Medical Center, New York City Health and Hospitals, The Bronx, NY, USA.; First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Gokulnath P; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Li G; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Hutchins E; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, USA.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Meechoovet B; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, USA., Sheng Q; Department of Biostatistics (Q.S.), Vanderbilt University Medical Center, Nashville, TN., Chatterjee E; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Sharma R; Collaborative Center for Translational Mass Spectrometry, Translational Genomics Research Institute, Phoenix, AZ, USA.; Cancer & Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ., Carnel-Amar N; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Lin C; Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Azzam C; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Ghaeli I; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Amancherla KV; Vanderbilt Translational and Clinical Research Center (R.S.), Vanderbilt University Medical Center, Nashville, TN, USA., Victorino JF; Cancer & Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ., Garcia-Mansfield K; Collaborative Center for Translational Mass Spectrometry, Translational Genomics Research Institute, Phoenix, AZ, USA.; Cancer & Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ., Pfeffer R; Masonic Medical Research Institute, Utica, NY, USA 13501., Sahu P; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Lindman BR; Vanderbilt Translational and Clinical Research Center (R.S.), Vanderbilt University Medical Center, Nashville, TN, USA., Elmariah S; Department of Medicine, Cardiovascular Division, University of California-San Francisco, San Francisco, CA, USA., Gamazon ER; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA., Betti MJ; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA., Bledsoe X; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA., Lance ML; Masonic Medical Research Institute, Utica, NY, USA 13501., Absi T; Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Su YR; Vanderbilt Translational and Clinical Research Center (R.S.), Vanderbilt University Medical Center, Nashville, TN, USA., Do N; Spectradyne LLC, Signal Hill, CA, USA., Contreras MG; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Varrias D; Albert Einstein College of Medicine/ Jacobi Medical Center, The Bronx, NY, USA., Kladas M; Albert Einstein College of Medicine/ North Central Bronx/Jacobi Medical Center, New York City Health and Hospitals, The Bronx, NY, USA., Radulovic M; Albert Einstein College of Medicine/ North Central Bronx/Jacobi Medical Center, New York City Health and Hospitals, The Bronx, NY, USA., Tsiachris D; First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Spanos A; Department of Cardiology, Athens Medical Center, Athens, Greece., Tsioufis K; First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Ellinor PT; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Tucker NR; SUNY Upstate Medical University, Syracuse, New York, USA., Januzzi JL; Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Baim Institute for Clinical Research, Boston, Massachusetts, USA., Pirrotte P; Collaborative Center for Translational Mass Spectrometry, Translational Genomics Research Institute, Phoenix, AZ, USA.; Cancer & Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ., Jovanovic-Talisman T; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Van Keuren-Jensen K; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, AZ, USA., Shah R; Vanderbilt Translational and Clinical Research Center (R.S.), Vanderbilt University Medical Center, Nashville, TN, USA., Das S; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Sep 22. Date of Electronic Publication: 2024 Sep 22.