15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism

Autor: Abis, G, Charles, RL, Kopec, J, Yue, WW, Atkinson, RA, Bui, TTT, Lynham, S, Popova, S, Sun, Y-B, Fraternali, F, Eaton, P, Conte, MR

Publikováno v: Abis, G, Charles, R L, Kopec, J, Yue, W W, Atkinson, R A, Bui, T T T, Lynham, S, Popova, S, Sun, Y-B, Fraternali, F, Eaton, P & Conte, M R 2019, ' 15-deoxy-Δ 12,14-Prostaglandin J 2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism ', Communications Biology, vol. 2, no. 1, 188 . https://doi.org/10.1038/s42003-019-0426-2
Communications Biology
Communications Biology, Nature Publishing Group, 2019, 2 (1), ⟨10.1038/s42003-019-0426-2⟩
Communications Biology, Vol 2, Iss 1, Pp 1-14 (2019)

Human soluble epoxide hydrolase (hsEH) is an enzyme responsible for the inactivation of bioactive epoxy fatty acids, and its inhibition is emerging as a promising therapeutical strategy to target hypertension, cardiovascular disease, pain and insulin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::171ef5494cea0bc031d1c2b36730d56c
http://ora.ox.ac.uk/objects/uuid:

[ANMCO/SICI-GISE document on antiplatelet therapy in patients with acute coronary syndrome]

Autor: De Luca, Leonardo, Bolognese, Leonardo, Valgimigli, Marco, Ceravolo, Roberto, Danzi, Gian Battista, Piccaluga, Emanuela, Rakar, Serena, Cremonesi, Alberto, Bovenzi, Francesco Maria, Abbate, R, Andreotti, F, Bolognese, L, Biondi Zoccai, G, Bovenzi, FM, Capodanno, D, Caporale, R, Capranzano, P, Carrabba, N, Casella, G, Cavallini, C, Ceravolo, R, Colombo, P, Conte, MR, Cordone, S, Cremonesi, A, Danzi, GB, Del Pinto, M, De Luca, G, De Luca, L, De Servi, S, Di Lorenzo, E, Di Pasquale, G, Farina, R, Fiscella, A, Formigli, D, Galli, S, Giudice, P, Gonzi, G, Greco, C, Grieco, NB, La Vecchia, L, Lazzari, M, Lettieri, C, Lettino, M, Limbruno, U, Lupi, A, Macchi, A, Marini, M, Marzilli, M, Montinaro, A, Musumeci, G, Navazio, A, Olivari, Z, Oltrona Visconti, L, Oreglia, JA, Ottani, F, Parodi, G, Pasquetto, G, Patti, G, Perkan, A, Perna, GP, Piccaluga, E, Piscione, F, Prati, F, Rakar, S, Ravasio, R, Ronco, F, Rossini, R, Rubboli, A, Saia, F, Sardella, G, Satullo, G, Savonitto, S, Sbarzaglia, P, Scorcu, G, Signore, N, Tarantini, G, Terrosu, P, Testa, L, Tubaro, M, Valente, S, Valgimigli, M, Varbella, F, Vatrano, M., ESPOSITO, GIOVANNI

Antiplatelet therapy is the cornerstone of the pharmacologic management of patients with acute coronary syndrome (ACS). Over the last years, several studies have evaluated old and new oral or intravenous antiplatelet agents in ACS patients. In partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::a7268b96b0da84ef194541f4087c2e19
http://hdl.handle.net/11588/614336

[Heart failure in Italian intensive cardiac care units: data from the BLITZ-3 survey]

Autor: Chinaglia, A, Casella, G, Scorcu, G, Cassin, M, Chiarella, F, Conte, Mr, Fradella, G, Lucci, D, Maggioni, Ap, Visconti, Lo, Autore, Camillo, Ricercatori dello Studio BLITZ, 3

Only limited information about clinical characteristics, diagnostic procedures and therapeutic options is available in patients admitted to an intensive cardiac care unit (ICCU) for heart failure. The aim of this study was to evaluate causes of admis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5bcda0b65aabeb860eab0876df11a84f
http://hdl.handle.net/11573/554115

Severe coronary artery disease after radiation therapy of the chest and mediastinum: clinical presentation and treatment

Autor: Fulvio Orzan, Brusca A, M C Figliomeni, Conte Mr, Patrizia Presbitero

Publikováno v: British heart journal. 69(6)

OBJECTIVE--To define the clinical and angiographic features and the therapeutic problems in patients with coronary artery disease after therapeutic irradiation of the chest. DESIGN--An observational retrospective study. SETTING--The cardiac catheteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ff614c097a15a980c92b3effde741c
https://pubmed.ncbi.nlm.nih.gov/8343315

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