In-depth quantitative proteomic characterization of organotypic hippocampal slice culture reveals sex-specific differences in biochemical pathways

Autor: Simone Nardin Weis, Jaques Miranda F. Souza, Juliana Bender Hoppe, Marina Firmino, Manfred Auer, Nassim N. Ataii, Leonardo Assis da Silva, Mariana Maier Gaelzer, Caroline Peres Klein, Alan R. Mól, Consuelo M. R. de Lima, Diogo Onofre Souza, Christianne G. Salbego, Carlos André O. Ricart, Wagner Fontes, Marcelo Valle de Sousa

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)

Abstract Sex differences in the brain of mammals range from neuroarchitecture through cognition to cellular metabolism. The hippocampus, a structure mostly associated with learning and memory, presents high vulnerability to neurodegeneration and agin

Externí odkaz: https://doaj.org/article/cfe2a9cf46204172b40da2ef677cf9aa

Exoproteome profiling of Trypanosoma cruzi during amastigogenesis early stages

Autor: Carlos André Ornelas Ricart, Samuel Coelho Mandacaru, Rayner M. L. Queiroz, Lucas Sousa de Oliveira, Sébastien Charneau, Consuelo M. R. de Lima, Jaime M. Santana, Izabela Marques Dourado Bastos, Peter Roepstorff, Marcos Rodrigo Alborghetti

Publikováno v: Mandacaru, S C, Queiroz, R M L, Alborghetti, M R, de Oliveira, L S, de Lima, C M R, Bastos, I M D, Santana, J M, Roepstorff, P, Ricart, C A O & Charneau, S 2019, ' Exoproteome profiling of Trypanosoma cruzi during amastigogenesis early stages ', PLOS ONE, vol. 14, no. 11, e0225386 . https://doi.org/10.1371/journal.pone.0225386
PLoS ONE, Vol 14, Iss 11, p e0225386 (2019)
PLoS ONE

Chagas disease is caused by the protozoan Trypanosoma cruzi, affecting around 8 million people worldwide. After host cell invasion, the infective trypomastigote form remains 2–4 hours inside acidic phagolysosomes to differentiate into replicative a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d3e1ebbc775bb7f787a9c1d80c6b60
https://findresearcher.sdu.dk:8443/ws/files/157065493/journal.pone.0225386.pdf

Presence of the cytolytic protein enterolobin in different developmental stages of Enterolobium contortisiliquum seeds

Autor: Marcelo Valle de Sousa, Carlos André Ornelas Ricart, Consuelo M. R. de Lima, Pedro J. P. Zanotta

Publikováno v: Brazilian Journal of Plant Physiology, Volume: 19, Issue: 2, Pages: 163-170, Published: JUN 2007

Enterolobin is a 52.9 kDa, cytolytic, inflammatory and insecticidal protein present in Enterolobium contortisiliquum (Vell.) Morong, a Brazilian large-sized tree. This protein was previously described to occur in different forms of association (monom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521868ccfaa0ec6d9a2eeffe67bba38d
https://doi.org/10.1590/s1677-04202007000200008

The plant cytolytic protein enterolobin assumes a dimeric structure in solution

Autor: Carlos André Ornelas Ricart, Luciano P. Silva, Ricardo B. Cunha, Ricardo Bentes Azevedo, Marcelo Valle de Sousa, Sı́lvia Elena Tolfo Bittencourt, Consuelo M. R. de Lima

Publikováno v: FEBS letters. 549(1-3)

Enterolobin is a plant cytolytic protein similar to the bacterial cytolysin aerolysin. Biochemical and biophysical techniques were used to verify if enterolobin, like aerolysin, adopts a dimeric structure in solution. SDS–PAGE showed bands correspo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf37d906c97e6f811305589e1f708161
https://pubmed.ncbi.nlm.nih.gov/12914923