Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Consuelo Guerri"'
Autor:
Susana Mellado, María José Morillo-Bargues, Carla Perpiñá-Clérigues, Francisco García-García, Victoria Moreno-Manzano, Consuelo Guerri, María Pascual
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1153-1163 (2025)
Our previous studies have reported that activation of the NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3)-inflammasome complex in ethanol-treated astrocytes and chronic alcohol-fed mice could be associated with neuroinflammation and brain da
Externí odkaz:
https://doaj.org/article/a2d94a3502b44ebab063e618e7ba85f6
Autor:
Carla Perpiñá-Clérigues, Susana Mellado, José F. Català-Senent, Francesc Ibáñez, Pilar Costa, Miguel Marcos, Consuelo Guerri, Francisco García-García, María Pascual
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Background Lipids represent essential components of extracellular vesicles (EVs), playing structural and regulatory functions during EV biogenesis, release, targeting, and cell uptake. Importantly, lipidic dysregulation has been linked to se
Externí odkaz:
https://doaj.org/article/809bb49be692495c9cb4f98403bed754
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Toll-like receptors (TLRs) represent critical effectors in the host defense response against various pathogens; however, their known function during development has also highlighted a potential role in cell fate determination and
Externí odkaz:
https://doaj.org/article/107ea10e881640b1a0e30ddd5378bbc6
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 5, Pp 796-801 (2020)
In recent years, a type of extracellular vesicles named exosomes has emerged that play an important role in intercellular communication under physiological and pathological conditions. These nanovesicles (30–150 nm) contain proteins, RNAs and lipid
Externí odkaz:
https://doaj.org/article/09b2e5f4efe347699c8bd999b7cbb8d4
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Current evidence indicates that extracellular vesicles (EVs) participate in intercellular signaling, and in the regulation and amplification of neuroinflammation. We have previously shown that ethanol activates glial cells through
Externí odkaz:
https://doaj.org/article/3c2ec334470b49969b68b879c4c8c1b4
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237066 (2020)
TLR4 is a member of the toll-like receptors (TLR) immune family, which are activated by lipopolysaccharide, ethanol or damaged tissue, among others, by triggering proinflammatory cytokines release and inflammation. Lack of TLR4 protects against infla
Externí odkaz:
https://doaj.org/article/b2f59f8061ef49a5b426fb67eb7fab12
Autor:
María Pascual, Jorge Montesinos, Sandra Montagud-Romero, Jerónimo Forteza, Marta Rodríguez-Arias, José Miñarro, Consuelo Guerri
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background Inflammation during brain development participates in the pathogenesis of early brain injury and cognitive dysfunctions. Prenatal ethanol exposure affects the developing brain and causes neural impairment, cognitive and behavioral
Externí odkaz:
https://doaj.org/article/c8ccb24d8f5b4aa9a1895c1b183f5081
Autor:
Eva M. Marco, Sara Peñasco, María-Donina Hernández, Anabel Gil, Erika Borcel, Marta Moya, Elena Giné, José Antonio López-Moreno, Consuelo Guerri, Meritxell López-Gallardo, Fernando Rodríguez de Fonseca
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
Alcohol is a serious public health concern that has a differential impact on individuals depending upon age and sex. Patterns of alcohol consumption have recently changed: heavy episodic drinking—known as binge-drinking—has become most popular am
Externí odkaz:
https://doaj.org/article/1a3639503ae04330b112e139a90aea64
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153097 (2016)
Ethanol induces brain damage and neurodegeneration by triggering inflammatory processes in glial cells through activation of Toll-like receptor 4 (TLR4) signaling. Recent evidence indicates the role of protein degradation pathways in neurodegeneratio
Externí odkaz:
https://doaj.org/article/e128ca6dd90247ef8d86a97e6158935b
Autor:
Enric Mocholí, Begoña Ballester-Lurbe, Gloria Arqué, Enric Poch, Blanca Peris, Consuelo Guerri, Mara Dierssen, Rosa M Guasch, José Terrado, Ignacio Pérez-Roger
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19236 (2011)
Rnd proteins are a subfamily of Rho GTPases involved in the control of actin cytoskeleton dynamics and other cell functions such as motility, proliferation and survival. Unlike other members of the Rho family, Rnd proteins lack GTPase activity and th
Externí odkaz:
https://doaj.org/article/1ba4100a36f144729fd2edde32470114