Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Consuelo Anzilotti"'
Autor:
Rose Hodgson, Xijin Xu, Consuelo Anzilotti, Mukta Deobagkar-Lele, Tanya L. Crockford, Jessica D. Kepple, Eleanor Cawthorne, Aneesha Bhandari, Alberto Cebrian-Serrano, Martin J. Wilcock, Benjamin Davies, Richard J. Cornall, Katherine R. Bull
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Despite an upregulation in anergic B cells, N-myc downstream-regulated gene 1 (NDRG1) is not required for the tolerogenic downstream responses, reducing risk of immune modulation on targeting of NDRG1 for cancer therapeutics.
Externí odkaz:
https://doaj.org/article/071960c232c647ea9fe3a78b10f61494
Autor:
Christopher Paluch, Ana Mafalda Santos, Consuelo Anzilotti, Richard J. Cornall, Simon J. Davis
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Antibodies that block the immune checkpoint receptors PD1 and CTLA4 have revolutionized the treatment of melanoma and several other cancers, but in the process, a new class of drug side effect has emerged—immune related adverse events. The observat
Externí odkaz:
https://doaj.org/article/673980b531654510a0d8ba4795ba7cb5
Autor:
Martin Fellermeyer, Consuelo Anzilotti, Christopher Paluch, Richard J Cornall, Simon J Davis, Uzi Gileadi
Publikováno v:
Immunotherapy Advances. 3
Summary There is an increasing number of immune-checkpoint inhibitors being developed and approved for cancer immunotherapy. Most of the new therapies aim to reactivate tumour-infiltrating T cells, which are responsible for tumour killing. However, i
Autor:
E. Bateman, Chantal E. Hargreaves, Arzoo M Patel, Smita Y. Patel, Consuelo Anzilotti, James E G Charlesworth, John Broxholme, Silvia Salatino, Sarah C. Sasson, Julian C. Knight
Publikováno v:
Journal of Clinical Immunology
Purpose Common variable immunodeficiency disorders (CVID) is characterized by low/absent serum immunoglobulins and susceptibility to bacterial infection. Patients can develop an infections-only phenotype or a complex disease course with inflammatory,
Autor:
Richard J. Cornall, Xijin Xu, Adam J. Mead, Mukta Deobagkar-Lele, Tanya L. Crockford, David Sims, Consuelo Anzilotti, Adam P. Cribbs, Katherine R. Bull
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The early life of an individual mouse is characterized by the generation of a population of long-lived and frequently autoreactive B cells, called B1 cells, which are largely developed in the fetal liver, whilst adult life is characteriz
Autor:
Chantal E. Hargreaves, Fatima Dhalla, Arzoo M. Patel, Andrés Caballero Garcia de Oteyza, Elizabeth Bateman, Joanne Miller, Consuelo Anzilotti, Lisa Ayers, Bodo Grimbacher, Smita Y. Patel
Publikováno v:
Clinical immunology (Orlando, Fla.). 234
Genetic variants in PIK3CD, PIK3R1 and NFKB1 cause the primary immune deficiencies, activated PI3Kδ syndrome (APDS) 1, APDS2 and NFκB1 haploinsufficiency, respectively. We have identified a family with known or potentially pathogenic variants NFKB1
Autor:
Renaud Lesourne, Tanya L. Crockford, Ekaterina Zvezdova, Marlène Marcellin, Delphine Baup, Daian Cheng, Richard J. Cornall, Katherine R. Bull, Mukta Deobagkar-Lele, Seeyoung Choi, Shoji Uehara, Paul E. Love, Claude Warzecha, Sophia C. Bennett, Consuelo Anzilotti, Anne Gonzalez de Peredo, Helen Ferry
Publikováno v:
Nature Immunology
Nature Immunology, Nature Publishing Group, 2017, 18 (2), pp.205-213. ⟨10.1038/ni.3642⟩
Nature Immunology, Nature Publishing Group, 2017, 18 (2), pp.205-213. ⟨10.1038/ni.3642⟩
The positive and negative selection of lymphocytes by antigen is central to adaptive immunity and self-tolerance, yet how this is determined by different antigens is not completely understood. We found that thymocyte-selection-associated family membe
Autor:
M Aßmann, Christian Eggeling, Kristina A. Ganzinger, Steven F. Lee, Marco Fritzsche, Iztok Urbančič, Simon J. Davis, David Klenerman, Richard J. Cornall, Falk Schneider, Aleks Ponjavic, Michael L. Dustin, Ricardo A. Fernandes, M J Wilcock, Ana Filipa L.O.M. Santos, James McColl, David Depoil, J B de la Serna, Consuelo Anzilotti
Publikováno v:
Nat Immunol
Nature Immunology
Nature Immunology
To the editor — Full understanding of lymphocyte activation will require thorough characterization of the ‘resting’ state and how it changes. Surfaces coated with the cationic homopolymer poly-L-lysine (PLL) are widely used for total internal r
Publikováno v:
Clin Exp Immunol
Summary Various reports of disease-related lung pathologies in common variable immunodeficiency disorder (CVID) patients have been published, with differing histological and high-resolution computed tomography (HRCT) findings. Data were extracted fro
Autor:
Tarana Singh Dang, Karin R. Engelhardt, John C. Christianson, Eleanor Cawthorne, M. Teresa de la Morena, David J. Swan, Mirjam van der Burg, Bertrand Boisson, Stuart G. Tangye, Yaobo Xu, J. Ross Chapman, Sarah J. de Jong, Consuelo Anzilotti, T. Ronan Leahy, Pauline Chabosseau, Stefan Przyborski, Mary Ellen Conley, Andreas Werner, B. Christoffer Lagerholm, Adam P. Cribbs, Emma J. Fenech, Cindy S. Ma, David Sims, Mauro Santibanez Koref, Catarina Oliveira, Xijin Xu, Andrew J. Cant, Rui Chen, Luis Alvarez, Sophie Hambleton, Benjamin Davies, Mukta Deobagkar-Lele, Ralph S. Shapiro, Amy Fearn, Jennifer M. Puck, Katherine R. Bull, Jean-Laurent Casanova, Sergi Padilla-Parra, Bert van den Berg, Guy A. Rutter, John A. McGrath, Rolando Berlinguer-Palmini, Tanya L. Crockford, Richard J. Cornall, Gary Kleiner
Publikováno v:
Nature Immunology, 20(3), 350-361. Nature Publishing Group
Nature immunology, 2019, Vol.20, pp.350-361 [Peer Reviewed Journal]
Nature immunology, 2019, Vol.20, pp.350-361 [Peer Reviewed Journal]
Despite the known importance of zinc for human immunity, molecular insights into its roles have remained limited. Here we report a novel autosomal recessive disease characterized by absent B cells, agammaglobulinemia and early onset infections in fiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099fd5c1ef6e980ad413f7eec969f9c6
https://pure.eur.nl/en/publications/7a64427a-a297-4747-b5f9-217541748147
https://pure.eur.nl/en/publications/7a64427a-a297-4747-b5f9-217541748147