Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Constanze Uhlmann"'
Autor:
Dilaware Khan, Ann-Christin Nickel, Sebastian Jeising, Constanze Uhlmann, Sajjad Muhammad, Daniel Hänggi, Igor Fischer, Ulf Dietrich Kahlert
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 919 (2021)
Human induced pluripotent stem cells (hiPSCs) have emerged as a powerful tool for in vitro modelling of diseases with broad application in drug development or toxicology testing. These assays usually require large quantities of hiPSC, which can entai
Externí odkaz:
https://doaj.org/article/78dc7339f6c44edf9b020145692424c1
Autor:
Constanze Uhlmann, Ann‐Christin Nickel, Daniel Picard, Andrea Rossi, Guanzhang Li, Barbara Hildebrandt, Gabriele Brockerhoff, Farina Bendt, Ulrike Hübenthal, Michael Hewera, Hans‐Jakob Steiger, Dagmar Wieczorek, Aristoteles Perrakis, Wei Zhang, Marc Remke, Katharina Koch, Julia Tigges, Roland S. Croner, Ellen Fritsche, Ulf D. Kahlert
Publikováno v:
Biotechnology Journal. 17:2100693
Limitations in genetic stability and recapitulating accurate physiological disease properties challenge the utility of patient-derived (PD) cancer models for reproducible and translational research. A portfolio of isogenic human induced pluripotent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6271db99e05aadef3e3a01fa8c12014c
https://doi.org/10.1002/biot.202100693
https://doi.org/10.1002/biot.202100693
Autor:
Karl Köhrer, Jaroslaw Maciaczyk, Philippe Aretz, Ulf Dietrich Kahlert, Guido Reifenberger, Hans-Jakob Steiger, Constanze Uhlmann, Abigail K. Suwala, Isabella Ogorek, Dayana Herrera Rios, Katharina Koch, Jörg Felsberg, René Deenen
Publikováno v:
Oncotarget
Glioblastoma is the most aggressive type of glioma. The Wingless (Wnt) signaling pathway has been shown to promote stem cell properties and resistance to radio- and chemotherapy in glioblastoma. Here, we demonstrate that pharmacological Wnt pathway i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c80a578d999a410cb217eecb967282
https://doi.org/10.18632/oncotarget.25210
https://doi.org/10.18632/oncotarget.25210
Publikováno v:
Current protocols in stem cell biologyLiterature Cited. 52(1)
TP53 point mutations are found in 50% of all cancers and seem to play an important role in cancer pathogenesis. Thus, human induced pluripotent stem cells (hiPSCs) overexpressing mutant TP53 are a valuable tool for the generation of in vitro models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197ecd19dcf1fc9a9ed8197bbc18c047
https://pubmed.ncbi.nlm.nih.gov/31883435
https://pubmed.ncbi.nlm.nih.gov/31883435
Autor:
Thorsten Kloesges, Anika Schnake, Constanze Uhlmann, Sophie de Vries, Janina K. von Dahlen, Laura E. Rose
Publikováno v:
Molecular Plant Pathology. 18:110-124
Phytophthora infestans is a devastating pathogen in agricultural systems. Recently, an RNA silencing suppressor (PSR2, 'Phytophthora suppressor of RNA silencing 2') has been described in P. infestans. PSR2 has been shown to increase the virulence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db39050c2edde41ef0da17c2a6ea6cf4
https://doi.org/10.1111/mpp.12465
https://doi.org/10.1111/mpp.12465
Autor:
Sophie, de Vries, Janina K, von Dahlen, Constanze, Uhlmann, Anika, Schnake, Thorsten, Kloesges, Laura E, Rose
Publikováno v:
Molecular Plant Pathology
Summary Phytophthora infestans is a devastating pathogen in agricultural systems. Recently, an RNA silencing suppressor (PSR2, ‘Phytophthora suppressor of RNA silencing 2’) has been described in P. infestans. PSR2 has been shown to increase the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::152566cd6bbbbc904b1e0bf7a7bdeff2
https://pubmed.ncbi.nlm.nih.gov/27503598
https://pubmed.ncbi.nlm.nih.gov/27503598