Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Constanze Schwarz"'
1
Akademický článek
Novel pre-clinical mouse models for chronic Graft-versus-Host Disease
Autor: Lydia Verlaat, Katarina Riesner, Martina Kalupa, Beate Jung, Sarah Mertlitz, Constanze Schwarz, Jörg Mengwasser, Claudine Fricke, Olaf Penack
Publikováno v: Frontiers in Immunology, Vol 13 (2023)
Despite considerable progress in allogeneic hematopoietic cell transplantation (allo-HCT) has been achieved over the past years, chronic Graft-versus-Host Disease (cGvHD) still contributes to high morbidity rates, thus remaining a major hurdle in all
Externí odkaz: https://doaj.org/article/21a88827c2314acb894121df54f7ea79
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2
Akademický článek
Reduced Calcium Signaling Is Associated With Severe Graft-Versus-Host Disease: Results From Preclinical Models and From a Prospective EBMT Study
Autor: Katarina Riesner, Steffen Cordes, Christophe Peczynski, Martina Kalupa, Constanze Schwarz, Yu Shi, Sarah Mertlitz, Jörg Mengwasser, Steffie van der Werf, Zinaida Peric, Christian Koenecke, Helene Schoemans, Rafael F. Duarte, Grzegorz W. Basak, Olaf Penack
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Despite its involvement in various immune functions, including the allogeneic activation of T-lymphocytes, the relevance of calcium (Ca2+) for GVHD pathobiology is largely unknown. To elucidate a potential association between Ca2+and GVHD, we analyze
Externí odkaz: https://doaj.org/article/e59ca598aa1d40e5bdfa7137453851f6
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4
Enhanced Death Ligand-Induced Apoptosis in Cutaneous SCC Cells by Treatment with Diclofenac/Hyaluronic Acid Correlates with Downregulation of c-FLIP
Autor: Frank K. Braun, Lothar F. Fecker, Eggert Stockfleth, Martin Leverkus, Anja Köhler, Constanze Schwarz, Jürgen Eberle, Paul M. Rodust
Publikováno v: Journal of Investigative Dermatology. 130(8):2098-2109
Actinic keratosis (AK) occurs on sun-exposed skin and may progress to invasive squamous cell carcinoma (SCC). As for its topical treatment, diclofenac/hyaluronic acid (HA) has been recently approved. The NSAID diclofenac is an inhibitor of COX-2; how
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15419c1ba25a2d3179bffcf04fa595a
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5
Efficient and selective tumor cell lysis and induction of apoptosis in melanoma cells by a conditional replication-competent CD95L adenovirus
Autor: Stefanie Jost, Amir M. Hossini, Almudena Hurtado Picó, Lothar F. Fecker, Magdalena Schmude, Xiaomin Wang, Jürgen Eberle, Henry Fechner, Constanze Schwarz
Publikováno v: Experimental Dermatology. 19:e56-e66
The high mortality of melanoma demands the development of new strategies, and gene therapy may be considered provided improvements in efficacy and selectivity. Overexpression of the death ligand CD95L/FasL has been shown in previous studies as highly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f73d7fd5cdaba5b1a2b1c3fbaa5a040e
https://doi.org/10.1111/j.1600-0625.2009.00977.x
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6
Loss of Proapoptotic Bcl-2-Related Multidomain Proteins in Primary Melanomas Is Associated with Poor Prognosis
Autor: Georgi Tchernev, Bachtier M. Kurbanov, Lothar F. Fecker, Jürgen Eberle, Chalid Assaf, Constanze Schwarz, Uwe Trefzer, Christoph C. Geilen, Peter T. Daniel
Publikováno v: Journal of Investigative Dermatology. 126:1366-1371
Prognosis of primary melanoma is presently based on morphological parameters, mainly tumor thickness. However, more reliable prognostic markers are needed that allow a better stratification of patients, especially with regard to therapeutic options.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab0fcf13485a2497d84f4653774a5a7
https://doi.org/10.1038/sj.jid.5700192
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7
Synthesis, Storage, and Release of Vascular Endothelial Growth Factor/Vascular Permeability Factor (VEGF/VPF) by Human Mast Cells: Implications for the Biological Significance of VEGF206
Autor: Heidi Kögel, Constanze Schwarz, Hans Baumeister, Beate M. Henz, Andreas Grützkau, A. Möller, Sabine Krüger-Krasagakes, Pia Welker, Undine Lippert
Publikováno v: Molecular Biology of the Cell. 9:875-884
Mast cells have been implicated in various diseases that are accompanied by neovascularization. The exact mechanisms by which mast cells might mediate an angiogenic response, however, are unclear and therefore, we have investigated the possible expre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42a5847f15e75218ee6fec16a9b4768
https://doi.org/10.1091/mbc.9.4.875
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9
Efficient and selective tumor cell lysis and induction of apoptosis in melanoma cells by a conditional replication-competent CD95L adenovirus
Autor: Lothar F, Fecker, Magdalena, Schmude, Stefanie, Jost, Amir M, Hossini, Almudena Hurtado, Picó, Xiaomin, Wang, Constanze, Schwarz, Henry, Fechner, Jürgen, Eberle
Publikováno v: Experimental dermatology. 19(8)
The high mortality of melanoma demands the development of new strategies, and gene therapy may be considered provided improvements in efficacy and selectivity. Overexpression of the death ligand CD95L/FasL has been shown in previous studies as highly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a422637c51ccf0e7a214c0d5c7cc7d6
https://pubmed.ncbi.nlm.nih.gov/19725869
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10
Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells
Autor: Wolfram Sterry, Lothar F. Fecker, Horst Dürkop, Peter Walden, Frank K. Braun, Constanze Schwarz, Chalid Assaf, Jürgen Eberle
Publikováno v: The Journal of investigative dermatology. 127(10)
Control of apoptosis via death ligands plays a basic role for lymphocyte homeostasis and lymphoma development. In this study, cutaneous T-cell lymphoma (CTCL) cell lines revealed pronounced resistance to death ligands as compared to cell lines of T-c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11fae26519a957e9f361d9ebbc631ea
https://pubmed.ncbi.nlm.nih.gov/17495957
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