Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Constanze A, Jakwerth"'
Autor:
Constanze A. Jakwerth, Vincent Grass, Anna Erb, Andreas Pichlmair, Georg Boonen, Veronika Butterweck, Carsten B. Schmidt-Weber
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115959- (2024)
Background: The intensified search for low-threshold herbal anti-viral drugs would be of great advantage in prevention of early stages of infection. Since the SARS-CoV-2 Omicron variant has prevailed in western countries, the course has only been mil
Externí odkaz:
https://doaj.org/article/fe252ac7af3541b4955fbf13f5f235bb
Autor:
Constanze A. Jakwerth, Hannah Kitzberger, Dimitrii Pogorelov, Annika Müller, Simon Blank, Carsten B. Schmidt-Weber, Ulrich M. Zissler
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
MicroRNAs (miRs) have gained scientific attention due to their importance in the pathophysiology of allergic diseases as well as their potential as biomarkers in allergen-specific treatment options. Their function as post-transcriptional regulators,
Externí odkaz:
https://doaj.org/article/a4cfb817e63a4d98ba32ca3afa20226d
Autor:
Stephanie Musiol, Francesca Alessandrini, Constanze A. Jakwerth, Adam M. Chaker, Evelyn Schneider, Ferdinand Guerth, Benjamin Schnautz, Johanna Grosch, Ileana Ghiordanescu, Julia T. Ullmann, Josephine Kau, Mirjam Plaschke, Stefan Haak, Thorsten Buch, Carsten B. Schmidt-Weber, Ulrich M. Zissler
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
TGF-β1 is known to have a pro-inflammatory impact by inducing Th9 and Th17 cells, while it also induces anti-inflammatory Treg cells (Tregs). In the context of allergic airway inflammation (AAI) its dual role can be of critical importance in influen
Externí odkaz:
https://doaj.org/article/2107742a722a4451ab2e2106650214cb
Autor:
Anna Erb, Ulrich M. Zissler, Madlen Oelsner, Adam M. Chaker, Carsten B. Schmidt-Weber, Constanze A. Jakwerth
Publikováno v:
Biosensors, Vol 12, Iss 11, p 929 (2022)
Biosensors such as toll-like receptors (TLR) induce the expression of interferons (IFNs) after viral infection that are critical to the first step in cell-intrinsic host defense mechanisms. Their differential influence on epithelial integrity genes,
Externí odkaz:
https://doaj.org/article/347b9773ae1e4dd7b3c47cbc93dafea7
Autor:
Constanze A. Jakwerth, Jose Ordovas-Montanes, Simon Blank, Carsten B. Schmidt-Weber, Ulrich M. Zissler
Publikováno v:
Cells, Vol 11, Iss 9, p 1387 (2022)
The airway epithelium provides the first line of defense to the surrounding environment. However, dysfunctions of this physical barrier are frequently observed in allergic diseases, which are tightly connected with pro- or anti-inflammatory processes
Externí odkaz:
https://doaj.org/article/0aa63b9eb8884d5d95c35bf01ef1c5d0
Autor:
Johannes Grosch, Antoine Lesur, Stéphanie Kler, François Bernardin, Gunnar Dittmar, Elisabetta Francescato, Simon J. Hewings, Constanze A. Jakwerth, Ulrich M. Zissler, Matthew D. Heath, Markus Ollert, Matthias F. Kramer, Christiane Hilger, Maria Beatrice Bilò, Carsten B. Schmidt-Weber, Simon Blank
Publikováno v:
Toxins, Vol 14, Iss 4, p 284 (2022)
Allergy to Polistes dominula (European paper wasp) venom is of particular relevance in Southern Europe, potentially becoming a threat in other regions in the near future, and can be effectively cured by venom immunotherapy (VIT). As allergen content
Externí odkaz:
https://doaj.org/article/9dd7396232544d4c823462a5d47153c8
Autor:
Ulrich M. Zissler, Constanze A. Jakwerth, Ferdinand M. Guerth, Lisa Pechtold, Juan Antonio Aguilar-Pimentel, Katharina Dietz, Kathrin Suttner, Guido Piontek, Bernhard Haller, Zuzana Hajdu, Matthias Schiemann, Carsten B. Schmidt-Weber, Adam M. Chaker
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 475-488 (2018)
Background: Allergen-specific immunotherapy (AIT) is a causative treatment in allergic airway disease, comprising long-term allergen administration and requiring three years of treatment. Mechanisms and biomarkers that translate into clinical efficac
Externí odkaz:
https://doaj.org/article/8745664df04b40409aa0082b5e9a8c7a
Publikováno v:
Expert Review of Molecular Diagnostics. 22:983-986
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a81b82c2afcbb12701466c0fb611d5
https://doi.org/10.1080/14737159.2022.2153038
https://doi.org/10.1080/14737159.2022.2153038
Autor:
Carsten Schmidt-Weber, Sebastian Kotz, Adam Chaker, Mirjam Plaschke, Shu-Hung Wang, Ferdinand Guerth, Sonja Heine, Alexander Heldner, Julia T Ullmann, Maren Buettner, Francesca Alessandrini, Ulrich M. Zissler, Lisa Pechtold, Constanze A. Jakwerth, Simon Blank, Josephine Kau, Madlen Oelsner
Publikováno v:
Allergy 76, 2827-2839 (2021)
BACKGROUND Studies show that proallergic TH 2 cells decrease after successful allergen-specific immunotherapy (AIT). It is likely that iatrogenic administration of allergens drives these cells to exhaustion due to chronic T-cell receptor stimulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b37bb7265f1742336a233f75dda4c14
https://doi.org/10.1111/all.14896
https://doi.org/10.1111/all.14896
Autor:
Georg Jocher, Vincent Grass, Sarah K Tschirner, Lydia Riepler, Stephan Breimann, Tuğberk Kaya, Madlen Oelsner, M Sabri Hamad, Laura I Hofmann, Carl P Blobel, Carsten B Schmidt‐Weber, Ozgun Gokce, Constanze A Jakwerth, Jakob Trimpert, Janine Kimpel, Andreas Pichlmair, Stefan F Lichtenthaler
Publikováno v:
EMBO Rep. 23:e54305 (2022)
EMBO reports 23(6), e54305 (2022). doi:10.15252/embr.202154305
EMBO reports 23(6), e54305 (2022). doi:10.15252/embr.202154305
The severe‐acute‐respiratory‐syndrome‐coronavirus‐2 (SARS‐CoV‐2) is the causative agent of COVID‐19, but host cell factors contributing to COVID‐19 pathogenesis remain only partly understood. We identify the host metalloprotease ADA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa416da9c2b0eb78067136b09f89a20
https://doi.org/10.15252/embr.202154305
https://doi.org/10.15252/embr.202154305