Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Constanze, Schmidt"'
Autor:
Felix Wiedmann, Max Jamros, Valerie Herlt, Amelie Paasche, Manuel Kraft, Moritz Beck, Merten Prüser, Atilla Erkal, Maren Harder, Marcin Zaradzki, Jasmin Soethoff, Matthias Karck, Norbert Frey, Constanze Schmidt
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
BackgroundElectrocardiographic (ECG) features of left bundle branch (LBB) block (LBBB) can be observed in up to 20%–30% of patients suffering from heart failure with reduced ejection fraction. However, predicting which LBBB patients will benefit fr
Externí odkaz:
https://doaj.org/article/709a03ae53bc42ab80780c19469bb3d4
Autor:
Frederik Heun, Tobias Niebuhr, Alvaro Gutierrez Bautista, Felix Wiedmann, Nicole Verhaar, Sabine Kästner, Karsten Feige, Constanze Schmidt
Publikováno v:
Animals, Vol 13, Iss 17, p 2724 (2023)
Case Summary: A two-year-old donkey presented with recurrent syncope. Electrocardiography revealed periods without any atrioventricular conduction and without any ventricular escape rhythm with a duration of up to one minute. Finally, atrioventricula
Externí odkaz:
https://doaj.org/article/c15bf7fd179c4d4a9365cbb4e2bd20fa
Autor:
Felix Wiedmann, Manuel Kraft, Stefan Kallenberger, Antonius Büscher, Amelie Paasche, Pablo L. Blochberger, Timon Seeger, Natasa Jávorszky, Gregor Warnecke, Rawa Arif, Jamila Kremer, Matthias Karck, Norbert Frey, Constanze Schmidt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 7 (2022)
Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. However, underlying molecular mechanisms are insufficiently understood. Previous studies suggested that microRNA (miRNA) dependent gene regulation plays an important
Externí odkaz:
https://doaj.org/article/9ddec92a514b466baa28b501ea914138
Autor:
Felix Wiedmann, Aytug K. Kiper, Mauricio Bedoya, Antonius Ratte, Susanne Rinné, Manuel Kraft, Maximilian Waibel, Priya Anad, Wolfgang Wenzel, Wendy González, Hugo A. Katus, Niels Decher, Constanze Schmidt
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 5, Pp 1223-1235 (2019)
Externí odkaz:
https://doaj.org/article/e40663fa70fb439ab236117496184d8c
Autor:
Felix Wiedmann, Hüseyin Ince, Christoph Stellbrink, Thomas Kleemann, Lars Eckardt, Johannes Brachmann, Bernd-Dieter Gonska, Stefan Kääb, Christian A. Perings, Werner Jung, Patrick Lugenbiel, Matthias Hochadel, Jochen Senges, Norbert Frey, Constanze Schmidt
Publikováno v:
Heart Rhythm. 20:501-509
Because of its antiarrhythmic potency and due to the lack of alternatives, amiodarone is often used for antiarrhythmic therapy in patients with ICD or CRT-D systems. To date, robust data on the safety and clinical benefit of amiodarone therapy in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43af7a78a14eec7eddb9c6c455ac4d69
https://doi.org/10.1016/j.hrthm.2022.12.009
https://doi.org/10.1016/j.hrthm.2022.12.009
Autor:
Elisa Darkow, Thong T. Nguyen, Marina Stolina, Fabian A. Kari, Constanze Schmidt, Felix Wiedmann, István Baczkó, Peter Kohl, Sridharan Rajamani, Ursula Ravens, Rémi Peyronnet
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
In search of more efficacious and safe pharmacological treatments for atrial fibrillation (AF), atria-selective antiarrhythmic agents have been promoted that target ion channels principally expressed in the atria. This concept allows one to engage an
Externí odkaz:
https://doaj.org/article/ddf44bced1ca4c75b664065aa511da6e
Autor:
Manuel Kraft, Antonius Büscher, Felix Wiedmann, Yannick L’hoste, Walter E. Haefeli, Norbert Frey, Hugo A. Katus, Constanze Schmidt
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Atrial fibrillation (AF) is the most common sustained arrhythmia with a prevalence of up to 4% and an upwards trend due to demographic changes. It is associated with an increase in mortality and stroke incidences. While stroke risk can be significant
Externí odkaz:
https://doaj.org/article/f3fc694076744efe853c265b4efa84c3
Autor:
Felix Wiedmann, Christoph Beyersdorf, Xiao-Bo Zhou, Manuel Kraft, Kathrin I. Foerster, Ibrahim El-Battrawy, Siegfried Lang, Martin Borggrefe, Walter E. Haefeli, Norbert Frey, Constanze Schmidt
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
BackgroundUpregulation of the two-pore-domain potassium channel TASK-1 (hK2P3.1) was recently described in patients suffering from atrial fibrillation (AF) and resulted in shortening of the atrial action potential. In the human heart, TASK-1 channels
Externí odkaz:
https://doaj.org/article/54eddb22db5b4324b5ea8376b0a17eda
Autor:
Felix Wiedmann, Christoph Beyersdorf, Xiaobo Zhou, Antonius Büscher, Manuel Kraft, Jendrik Nietfeld, Teo Puig Walz, Laura A. Unger, Axel Loewe, Bastian Schmack, Arjang Ruhparwar, Matthias Karck, Dierk Thomas, Martin Borggrefe, Gunnar Seemann, Hugo A. Katus, Constanze Schmidt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 10 (2020)
Background The tandem of P domains in a weak inward rectifying K+ channel (TWIK)‐related acid‐sensitive K+ channel (TASK‐1; hK2P3.1) two‐pore–domain potassium channel was recently shown to regulate the atrial action potential duration. In t
Externí odkaz:
https://doaj.org/article/7d75362eb0664a31a7186e77361b2a01
Autor:
Manuel Kraft, Kathrin I. Foerster, Felix Wiedmann, Max Sauter, Amelie Paasche, Pablo L. Blochberger, Baran Yesilgöz, Yannick L’hoste, Norbert Frey, Walter E. Haefeli, Jürgen Burhenne, Constanze Schmidt
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 762 (2022)
Atrial fibrillation (AF) is an arrhythmia associated with an increased stroke risk and mortality rate. Current treatment options leave unmet needs in AF therapy. Recently, doxapram has been introduced as a possible new option for AF treatment in a po
Externí odkaz:
https://doaj.org/article/415913a1d75443cda2392d1ae85cfa39