Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Constanza Garcia-Keller"'
Autor:
María P. Avalos, Andrea S. Guzman, Constanza Garcia-Keller, Bethania Mongi-Bragato, María A. Esparza, Daiana Rigoni, Marianela A. Sanchez, Gastón D. Calfa, Flavia A. Bollati, Liliana M. Cancela
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Though the facilitating influence of stress on drug abuse is well documented, the mechanisms underlying this interaction have yet to be fully elucidated. The present study explores the neurobiological mechanisms underpinning the sensitized response t
Externí odkaz:
https://doaj.org/article/63ca43400b5d4d21a15ac08ca1f1839c
Autor:
Daiana Rigoni, Maria P. Avalos, Maria J. Boezio, Andrea S. Guzmán, Gaston D. Calfa, Eduardo M. Perassi, Silvia M. Pierotti, Mariano Bisbal, Constanza Garcia-Keller, Liliana M. Cancela, Flavia Bollati
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100349- (2021)
Actin dynamics in dendritic spines can be associated with the neurobiological mechanisms supporting the comorbidity between stress exposure and cocaine increase rewards. The actin cytoskeleton remodeling in the nucleus accumbens (NA) has been implica
Externí odkaz:
https://doaj.org/article/2021ec074ebd4c608e52d4ec0dc57cdc
Autor:
Liliana M. Cancela, Flavia Bollati, Andrea S. Guzmán, Bethania Mongi-Bragato, María Paula Avalos, Constanza Garcia-Keller
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Altered glutamate transmission within the nucleus accumbens (NAc) has been proposed as a central mechanism underlying behavioural sensitisation associated with repeated cocaine exposure. In addition to glutamate, enkephalin, an endogenous opioid pept
Autor:
Rusty W. Nall, Lauren N. Beloate, Michael E. Meyerink, Tiffany Penaloza, Jade Doolittle, Brett Froeliger, Peter W. Kalivas, Constanza Garcia‐Keller
Publikováno v:
Addiction biologyREFERENCES. 27(2)
Nicotine addiction is a chronic relapsing brain disorder, and cigarette smoking is the leading cause of preventable death in the United States. Currently, the most effective pharmacotherapy for smoking cessation is Varenicline (VRN), which reduces bo
Autor:
Sade Spencer, Madeline Hohmeister, Peter W. Kalivas, Daniela Neuhofer, Constanza Garcia-Keller, Lauren N. Beloate, Kailyn Seidling, Vivian C. Chioma
Given that 30% of chronic cannabis users develop cannabis use disorder (CUD), it is critical to identify neuroadaptations that contribute to this disease. The nucleus accumbens core (NAcore) is important for drug seeking and ~ 90% of all NAcore neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95a56f5ac686e62e71a7081c3b5986ae
https://doi.org/10.21203/rs.3.rs-864738/v1
https://doi.org/10.21203/rs.3.rs-864738/v1
Autor:
María Paula Avalos, Andrea Susana Guzman, Daiana Rigoni, Ezequiel Axel Gorostiza, Marianela Adela Sanchez, Bethania Mongi-Bragato, Constanza Garcia-Keller, Eduardo Marcelo Perassi, Miriam Beatriz Virgolini, Javier María Peralta Ramos, Pablo Iribarren, Gastón Diego Calfa, Flavia Andrea Bollati, Liliana Marina Cancela
Publikováno v:
Brain, behavior, and immunity. 101
Stressful experience-induced cocaine-related behaviors are associated with a significant impairment of glutamatergic mechanisms in the Nucleus Accumbens core (NAcore). The hallmarks of disrupted glutamate homeostasis following restraint stress are th
Autor:
Carmela M. Reichel, Jordan L Hopkins, Peter W. Kalivas, Anna Kruyer, Jordan S Carter, Ritchy Hodebourg, Angela M Kearns, Constanza Garcia-Keller
Publikováno v:
Neuropsychopharmacology
Exposure to acute stress can increase vulnerability to develop or express many psychiatric disorders, including post-traumatic stress disorder. We hypothesized that stress-induced psychiatric vulnerability is associated with enduring neuroplasticity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea689260e6c32560c13b29e3756ee24d
https://europepmc.org/articles/PMC8357931/
https://europepmc.org/articles/PMC8357931/
Autor:
Arthur C. Riegel, Alexander C.W. Smith, Peter W. Kalivas, William C. Buchta, Bethany Hines, Rajesh Khanna, Constanza Garcia-Keller, Aubin Moutal
Publikováno v:
Mol Neurobiol
Cocaine addiction is a major health concern with limited effective treatment options. A better understanding of mechanisms underlying relapse may help inform the development of new pharmacotherapies. Emerging evidence suggests that collapsin response
Autor:
Constanza Garcia-Keller, Peter W. Kalivas, Kaylee N. Hooker, Cassandra D. Gipson, Kah-Chung Leong, Sade Spencer, J.A. McFaddin, Carmela M. Reichel, Michael D. Scofield, Benjamin M. Siemsen
Publikováno v:
Neuroscience
Astrocytes provide support for neurons, regulate metabolic processes, and influence neuronal communication in a variety of ways, including through the homeostatic regulation of glutamate. Following 2-hour cocaine or methamphetamine self-administratio
Autor:
Ana L. Vivinetto, Clara Castañares, Constanza Garcia-Keller, Ana Lis Moyano, Cristian Falcon, Anabela Palandri, Victoria Rozés-Salvador, Juan I. Rojas, Liliana Patrucco, Clara Monferran, Liliana Cancela, Edgardo Cristiano, Ronald L. Schnaar, Pablo H.H. Lopez
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166324
Myelin-associated glycoprotein (MAG) is a key molecule involved in the nurturing effect of myelin on ensheathed axons. MAG also inhibits axon outgrowth after injury. In preclinical stroke models, administration of a function-blocking anti-MAG monoclo