Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Constanza, Morén"'
Autor:
V. F. E. D. Smolders, C. Rodríguez, I. Blanco, R. Szulcek, Wim Timens, L. Piccari, Y. Roger, X. Hu, Constanza Morén, C. Bonjoch, L. Sebastián, M. Castellà, J. Osorio, V. I. Peinado, Harm Jan Bogaard, P. H. A. Quax, M. Cascante, J. A. Barberà, O. Tura-Ceide
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH) are two forms of pulmonary hypertension (PH) characterized by obstructive vasculopathy. Endothelial dysfunction along with metabolic changes towa
Externí odkaz:
https://doaj.org/article/07d082571725443e8a4b358651954c32
Autor:
Olga Tura-Ceide, Valérie F. E. D. Smolders, Núria Aventin, Constanza Morén, Mariona Guitart-Mampel, Isabel Blanco, Lucilla Piccari, Jeisson Osorio, Cristina Rodríguez, Montserrat Rigol, Núria Solanes, Andrea Malandrino, Kondababu Kurakula, Marie Jose Goumans, Paul H. A. Quax, Victor I. Peinado, Manuel Castellà, Joan Albert Barberà
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Pulmonary endarterectomy (PEA) resected material offers a unique opportunity to develop an in vitro endothelial cell model of chronic thromboembolic pulmonary hypertension (CTEPH). We aimed to comprehensively analyze the endothelial function
Externí odkaz:
https://doaj.org/article/754ae83577394ffaaec8967753372381
Autor:
Ingrid González-Casacuberta, Dolores Vilas, Claustre Pont-Sunyer, Ester Tobías, Judith Cantó-Santos, Laura Valls-Roca, Francesc Josep García-García, Glòria Garrabou, Josep Maria Grau-Junyent, Maria Josep Martí, Francesc Cardellach, Constanza Morén
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Neurodegenerative diseases, such as Parkinson’s disease, are heterogeneous disorders with a multifactorial nature involving impaired bioenergetics. Stem-regenerative medicine and bioenergetics have been proposed as promising therapeutic targets in
Externí odkaz:
https://doaj.org/article/c50fb249254043e3997e8d8e11b21890
Autor:
Constanza Morén, Nina Treder, Albert Martínez-Pinteño, Natàlia Rodríguez, Néstor Arbelo, Santiago Madero, Marta Gómez, Sergi Mas, Patricia Gassó, Eduard Parellada
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2275 (2022)
Schizophrenia (SZ) is a deleterious brain disorder affecting cognition, emotion and reality perception. The most widely accepted neurochemical-hypothesis is the imbalance of neurotransmitter-systems. Depleted GABAergic-inhibitory function might produ
Externí odkaz:
https://doaj.org/article/3e9f690ab3c64f159799e4f8c0929a7f
Autor:
Nuria Bujan, Constanza Morén, Francesc J. García-García, Alberto Blázquez, Clara Carnicer, Ana Belén Cortés, Cristina González, Ester López-Gallardo, Ester Lozano, Sonia Moliner, Laura Gort, Ester Tobías, Aitor Delmiro, Miguel Ángel Martin, Miguel Ángel Fernández-Moreno, Eduardo Ruiz-Pesini, Elena Garcia-Arumí, Juan Carlos Rodríguez-Aguilera, Glòria Garrabou
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 741 (2022)
The quantification of mitochondrial respiratory chain (MRC) enzymatic activities is essential for diagnosis of a wide range of mitochondrial diseases, ranging from inherited defects to secondary dysfunctions. MRC lesion is frequently linked to extend
Externí odkaz:
https://doaj.org/article/d0611c0ec08947eb8c86d361cf171d51
Autor:
Maria Bañó, Constanza Morén, Sergio Barroso, Diana Luz Juárez, Mariona Guitart-Mampel, Ingrid González-Casacuberta, Judith Canto-Santos, Ester Lozano, Agathe León, Enric Pedrol, Òscar Miró, Ester Tobías, Josep Mallolas, Jhon F. Rojas, Francesc Cardellach, Esteban Martínez, Gloria Garrabou
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Background: Mitochondrial genome has been used across multiple fields in research, diagnosis, and toxicogenomics. Several compounds damage mitochondrial DNA (mtDNA), including biological and therapeutic agents like the human immunodeficiency virus (H
Externí odkaz:
https://doaj.org/article/742f6e2c08eb40bea0a5c226c37accaf
Autor:
Diana Luz Juárez-Flores, Ingrid González-Casacuberta, Mario Ezquerra, María Bañó, Francesc Carmona-Pontaque, Marc Catalán-García, Mariona Guitart-Mampel, Juan José Rivero, Ester Tobias, Jose Cesar Milisenda, Eduard Tolosa, Maria Jose Marti, Ruben Fernández-Santiago, Francesc Cardellach, Constanza Morén, Glòria Garrabou
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Mutations in leucine rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). Mitochondrial and autophagic dysfunction has been described as etiologic factors in different experimental models
Externí odkaz:
https://doaj.org/article/3b6607831b0d40529dfd25c7ca31b6a1
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder worldwide affecting 2–3% of the population over 65 years. This prevalence is expected to rise as life expectancy increases and diagnostic and therapeutic protocols i
Externí odkaz:
https://doaj.org/article/09ceac747d0f452c997398f45386cbf6
Autor:
Sergio Barroso, Constanza Morén, Àlex González-Segura, Neus Riba, Joan A Arnaiz, Marcela Manriquez, Gemina Santana, José L Blanco, María Larousse, Montse Loncà, Elisa de Lazzari, Jaume Llopis, Josep Mallolas, Oscar Miró, Xavier Carné, Jose M Gatell, Glòria Garrabou, Esteban Martínez
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216712 (2019)
ContextClassical antiretroviral agents may acutely impact on metabolic, mitochondrial, renal and hepatic function in HIV-infected and uninfected persons. Fusion and integrase inhibitors are supposed to be safer, but have been scarcely investigated. T
Externí odkaz:
https://doaj.org/article/4c124f1a401f4be3a266411b6c1a542d
Autor:
Laura García-Otero, Marta López, Mariona Guitart-Mampel, Constanza Morén, Anna Goncé, Carol Esteve, Laura Salazar, Olga Gómez, Josep María Martínez, Berta Torres, Sergi César, Glòria Garrabou, Fàtima Crispi, Eduard Gratacós
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213279 (2019)
BACKGROUND:Mitochondrial toxicity related to maternal combined antiretroviral treatment (cART) may have an impact on the heart of HIV-exposed uninfected (HEU) fetuses. Our objective was to evaluate fetal cardiovascular and mitochondrial biomarkers in
Externí odkaz:
https://doaj.org/article/a76bd6ed9d2f4e39bafc0a3cddb7ca30