Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Constantinos J. Limas"'
Autor:
Constantinos J. Limas, Dimitrios Degiannis, Christos Kroupis, Zaharias-Alexandros Anyfantakis, Dennis V. Cokkinos, Panagiotis Iakovis
Publikováno v:
Angiology. 62:55-61
Dilated cardiomyopathy (DCM) is associated with increased inflammatory response reflected among other markers in high-sensitivity C-reactive protein (hsCRP) and soluble interleukin-2 receptor (sIL-2R) levels. We examined prospectively 60 consecutive
Autor:
C. Hasikidis, Constantinos J. Limas, Christos Kroupis, J. Iakovou, A. Haidaroglou, Dennis V. Cokkinos
Publikováno v:
European Journal of Clinical Investigation. 33:443-448
Background Activation of T lymphocytes is thought to mediate myocardial dysfunction in dilated cardiomyopathy (CMP), probably through cytotoxic cytokines, but its value as a prognostic factor has not been evaluated. Methods For 2 years we prospective
Publikováno v:
European Journal of Clinical Investigation. 32:74-78
BACKGROUND Prolactin represents a stimulatory link between the neuroendocrine and immune systems, but its involvement in the neurohumoral adaptations to heart failure (HF) has not been explored. METHODS We prospectively studied 55 patients (45 males,
Autor:
Catherine Limas, Constantinos J. Limas
Publikováno v:
Clinical Immunology and Immunopathology. 68:204-207
Autor:
Catherine Limas, Charles F. Wooley, Robert Bair, Libby Sparks, Harisios Boudoulas, Harry L. Graber, Constantinos J. Limas
Publikováno v:
American Heart Journal. 124:1258-1263
Cardiac autoantibodies have been detected in a significant proportion of patients with dilated cardiomyopathy, but their relation to the pathogenesis of the disease remains unknown. This issue was examined in 41 members of an Ohio family with a herit
Autor:
Constantinos J. Limas, C J Limas
Publikováno v:
Heart. 67:402-405
OBJECTIVE--Immunological mechanisms have been implicated in the pathogenesis of human dilated cardiomyopathy. The presence of autoantibodies against the beta 1 adrenoceptor in a substantial proportion of patients with dilated cardiomyopathy has been
Publikováno v:
American Heart Journal. 123:967-970
Sera from patients with dilated cardiomyopathy contain autoantibodies modifying cardiac beta-adrenergic pathways. The influence of the methodology used to determine the prevalence of these antibodies was examined by comparing in 51 patients with idio
Autor:
C J Limas, Constantinos J. Limas
Publikováno v:
Circulation Research. 68:309-313
Short-term (5 days) administration of L-thyroxine (0.1 mg/kg i.p. daily) to adult Sprague-Dawley rats induces a modest degree of cardiac hypertrophy (22% increase in heart weight/body weight ratios) and directionally opposite changes in cardiac adren
Publikováno v:
American Heart Journal. 119:1322-1328
Autoantibodies against the cardiac beta 1-adrenoceptor are present in the sera of patients with idiopathic dilated cardiomyopathy and may modulate the responsiveness of cardiac beta-adrenergic pathways to agonists. The regulation of cardiac adenylate
Publikováno v:
The American Journal of Cardiology. 65:483-487
The mechanisms responsible for the decline in the density of beta-adrenoceptors in the failing myocardium have not been adequately defined. It is a possibility that the nature of the process leading to heart failure may determine, in large part, the