Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Constantinos G. Panousis"'
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 5, Pp 856-863 (2001)
The regulation of ATP-binding cassette transporter 1 (ABC-1) expression by cytokines present within the microenvironment of the atheroma may play an important role in determining the impact of reverse cholesterol transport on the atherosclerotic lesi
Externí odkaz:
https://doaj.org/article/6ff7ad4d49034e1fb91b7e8374a76085
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 1, Pp 75-83 (2000)
The Th1-derived cytokine gamma interferon, IFN-γ, is present within the microenvironment of an atheromatous lesion and likely contributes to lesion progression through macrophage activation. While the inflammatory effects of IFN-γ are well known, t
Externí odkaz:
https://doaj.org/article/e437bd1be28a4c64bb6c6fb4ed7e297f
Autor:
Sawa Ito, Constantinos G. Panousis, Alexander M. Rowe, Kedwin Ventura, Jennifer D. Roy, Stephanie Stras, Egidio Brocca-Cofano, Josh Kim, Mark J. Shlomchik, Warren D. Shlomchik
Publikováno v:
Cancer Research. 82:5189-5189
Hematopoietically-restricted minor histocompatibility antigens (miHAs) specific T cells can mediate graft-versus-leukemia and promote engraftment with a low risk of graft-vs-host disease in allogeneic stem cell transplantation (alloSCT). Thus the miH
Autor:
Sawa Ito, Constantinos G Panousis, Alexander M Rowe, Jennifer D Roy, Stephanie Stras, Jianjie Mi, Egidio Brocca-Cofano, Kedwin Ventura, Josh Kim, Mark J Shlomchik, Warren D. Shlomchik
Publikováno v:
Transplantation and Cellular Therapy. 28:S217
Autor:
Elias K. Halvas, Heather Sprenger, Ellen S. Chan, Jean W. Pape, Umesh G. Lalloo, Jane Hitti, Karin L. Klingman, Joseph Kabanda, Frank Taulo, John W. Mellors, Constantinos G. Panousis, Lu Zheng, Nagalingeswaran Kumarasamy, Deborah McMahon
Publikováno v:
Journal of AIDS & clinical research
Background: Intrapartum single-dose nevirapine (sdNVP) reduces HIV-1 perinatal transmission but selects NVP resistance among mothers and infants. We evaluated the frequency of antiretroviral resistance among infants with intrauterine HIV-1 infection
Publikováno v:
Atherosclerosis. 155:79-85
The expression of macrophage scavenger receptors is regulated by intracellular cholesterol levels, as well as by cytokines affecting macrophage effector functions. CD36, a member of the type B scavenger receptor family, will bind a variety of nonlipo
Publikováno v:
Lipids. 35:1239-1247
Macrophage activation has been recognized as playing a central role in chronic inflammatory diseases in general and more specifically, in the vascular wall during the progression of atherosclerotic lesions. Macrophage-activating factors present withi
Publikováno v:
Journal of Virology. 71:4752-4760
The latent membrane protein 2 (LMP2) of Epstein-Barr virus interferes with B-lymphocyte signal transduction through the immunoglobulin (Ig) receptor. Two isoforms of LMP2 exist and differ only in that one isoform (LMP2a) contains an N-terminal cytopl
Autor:
Henrietta Dehmlow, Constantinos G. Panousis, Pari Malherbe, Nicole A. Kratochwil, Sabine Kolczewski, Lothar Lindemann, Cornelia Hertel, Robert Narquizian, Andreas D. Christ, Marcel Winnig, Luke Green, Porter Richard Hugh Phillip, Lucinda Steward, Rainer E. Martin, Jay Patrick Slack, Uwe Grether, Silvia Gatti-McArthur, Wolfgang Guba, Marius C. Hoener
Publikováno v:
Current topics in medicinal chemistry. 11(15)
G protein-coupled receptors (GPCRs) share a common architecture consisting of seven transmembrane (TM) domains. Various lines of evidence suggest that this fold provides a generic binding pocket within the TM region for hosting agonists, antagonists,
Autor:
Constantinos G. Panousis, Cornelia Hertel, Holger Kühne, Fabienne Ricklin, Michael B. Otteneder, Nicole A. Kratochwil, Stephan Röver, Uwe Grether, Robert Narquizian, Jens-Uwe Peters, Henrietta Dehmlow, Aurelia Conte, Dominik Hainzl
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(18)
Pyrido pyrimidinones are selective agonists of the human high affinity niacin receptor GPR109A (HM74A). They show no activity on the highly homologous low affinity receptor GPR109B (HM74). Starting from a high throughput screening hit the in vitro ac