Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Constantinos Demetriou"'
Autor:
Constantinos Demetriou, Naila Abid, Michael Butterworth, Larissa Lezina, Pavandeep Sandhu, Lynne Howells, Ian R. Powley, James H. Pringle, Zahirah Sidat, Omar Qassid, Dave Purnell, Monika Kaushik, Kaitlin Duckworth, Helen Hartshorn, Anne Thomas, Jacqui A. Shaw, Marion MacFarlane, Catrin Pritchard, Gareth J. Miles
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Breast Cancer is the most common cancer among women globally. Despite significant improvements in overall survival, many tumours are refractory to therapy and so novel approaches are required to improve patient outcomes. We have evaluated pa
Externí odkaz:
https://doaj.org/article/e0e42b354faf4f46a4b07334d5c51938
Autor:
Constantinos Demetriou, Christina Eleftheria Tzeliou, Alexandros Androutsopoulos, Demeter Tzeli
Publikováno v:
Molecules, Vol 28, Iss 24, p 8016 (2023)
Boron presents an important role in chemistry, biology, and materials science. Diatomic transition-metal borides (MBs) are the building blocks of many complexes and materials, and they present unique electronic structures with interesting and peculia
Externí odkaz:
https://doaj.org/article/3c53515663dc4f4faf772ea1f072887f
Autor:
Rhian Evans, Lewis M. Watkins, Kristen Hawkins, Gabriella Santiago, Constantinos Demetriou, Michelle Naughton, Marie Dittmer, Mark I. Rees, Denise Fitzgerald, B. Paul Morgan, James W. Neal, Owain W. Howell
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
BackgroundThe extent of cortical pathology is an important determinant of multiple sclerosis (MS) severity. Cortical demyelination and neurodegeneration are related to inflammation of the overlying leptomeninges, a more inflammatory CSF milieu and wi
Externí odkaz:
https://doaj.org/article/96a8f935c0644fc9baef94130d00bb8b
Autor:
Sam Khan, Gareth J Miles, Constantinos Demetriou, Zahirah Sidat, Nalini Foreman, Kevin West, Ankur Karmokar, Lynne Howells, Catrin Pritchard, Anne L Thomas, Karen Brown
Publikováno v:
Mutagenesis. 37(5-6)
Colorectal cancer (CRC) is the second leading cause of cancer death in the UK. Novel therapeutic prevention strategies to inhibit the development and progression of CRC would be invaluable. Potential contenders include low toxicity agents such as die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d837383c4c1828c38bedcb0c263e034c
https://pubmed.ncbi.nlm.nih.gov/36426854
https://pubmed.ncbi.nlm.nih.gov/36426854
Autor:
Catrin Pritchard, Lynne M. Howells, Meeta Patel, Howard Pringle, Michael Butterworth, Ian R. Powley, James Cooper, Constantinos Demetriou, Marion MacFarlane, Giuditta Viticchiè, Gareth J Miles, Naila Abid
Publikováno v:
Journal of Visualized Experiments.
An understanding of drug resistance and the development of novel strategies to sensitize highly resistant cancers rely on the availability of suitable preclinical models that can accurately predict patient responses. One of the disadvantages of exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c66d5e261266960f14acf066e5ba17
https://doi.org/10.3791/62130-v
https://doi.org/10.3791/62130-v
Autor:
Angela Bridges, Sandrine Jayne, Jennifer Schofield, Ana Sousa Manso, Duncan S. Holmes, Xi-Ping Zhang, Larissa Lezina, Michael T. McCabe, Mark James Bamford, Anastasia Wyce, David Jonathan Hirst, Máire A. Convery, Tom Slocombe, Andrew C. Pearce, Don O. Somers, Simon D. Wagner, Paul Scott-Stevens, Ann Louise Walker, Jonathan P. Hutchinson, Constantinos Demetriou, Cassie Messenger, Melissa C. Musso, Sian Evans, Ruth C. Barber, Joanne Morley, Thomas Gobbetti
Publikováno v:
The Journal of Biological Chemistry
B-cell lymphoma 6 (BCL6) is a zinc finger transcriptional repressor possessing a BTB–POZ (BR-C, ttk, and bab for BTB; pox virus and zinc finger for POZ) domain, which is required for homodimerization and association with corepressors. BCL6 has mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c7e6fdf77eb69b9270c5b0a66260fc
https://doi.org/10.1016/j.jbc.2021.100928
https://doi.org/10.1016/j.jbc.2021.100928
The creation of new atmospheric particles via nucleation is an important source of the particles from which Cloud Condensation Nuclei (CCN) are formed. The new particle formation (NPF) process can significantly alter the atmospheric aerosol size dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49dab56be447c95056fa0ad89312c75
https://hdl.handle.net/20.500.14279/9450
https://hdl.handle.net/20.500.14279/9450
Background: The receptor-binding cancer antigen expressed on SiSo cells (RCAS1) is a human tumor-associated antigen that contributes to tumor progression by enabling cancer cells to evade immune surveillance. The present study aimed to evaluate the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::0e73f776933cd7b1874e2385a4863e45
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3153007
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3153007
Autor:
Constantinos Demetriou
Publikováno v:
Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. 13(3)
Premalignancies resulting from photodamage, such as actinic keratosis and carcinoma in situ, can be treated with various modalities. Most of these treatments may reverse or treat these conditions although they often involve considerable skin irritati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15137ea4a4ff362c726845a20170af1
https://pubmed.ncbi.nlm.nih.gov/21609213
https://pubmed.ncbi.nlm.nih.gov/21609213