Výsledky vyhledávání - "Constantino Sábado"

Akademický článek

Targeting of epigenetic regulators in neuroblastoma

Autor: Luz Jubierre, Carlos Jiménez, Eric Rovira, Aroa Soriano, Constantino Sábado, Luis Gros, Anna Llort, Raquel Hladun, Josep Roma, Josep Sánchez de Toledo, Soledad Gallego, Miguel F. Segura

Publikováno v: Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-12 (2018)

Cancer therapy: Exploring an epigenetic approach Treatments that target chromatin, the combination of DNA and proteins, are emerging as alternative ways to treat aggressive neuroblastomas, cancers of neural tissue. Altering the structure and function

Externí odkaz: https://doaj.org/article/44a3f605201c49468d79e2635c1fc5f8

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Akademický článek

Dickkopf-1 Inhibition Reactivates Wnt/β-Catenin Signaling in Rhabdomyosarcoma, Induces Myogenic Markers In Vitro and Impairs Tumor Cell Survival In Vivo

Autor: Irina Giralt, Gabriel Gallo-Oller, Natalia Navarro, Patricia Zarzosa, Guillem Pons, Ainara Magdaleno, Miguel F. Segura, Constantino Sábado, Raquel Hladun, Diego Arango, José Sánchez de Toledo, Lucas Moreno, Soledad Gallego, Josep Roma

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 23, p 12921 (2021)

The Wnt/β-catenin signaling pathway plays a pivotal role during embryogenesis and its deregulation is a key mechanism in the origin and progression of several tumors. Wnt antagonists have been described as key modulators of Wnt/β-catenin signaling

Externí odkaz: https://doaj.org/article/427ff2b3d2834e329df4e183f7b4331d

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Akademický článek

Burkitt-like lymphoma with 11q aberration: a germinal center-derived lymphoma genetically unrelated to Burkitt lymphoma

Autor: Blanca Gonzalez-Farre, Joan Enric Ramis-Zaldivar, Julia Salmeron-Villalobos, Olga Balagué, Verónica Celis, Jaime Verdu-Amoros, Ferran Nadeu, Constantino Sábado, Antonio Ferrández, Marta Garrido, Federico García-Bragado, María Dolores de la Maya, José Manuel Vagace, Carlos Manuel Panizo, Itziar Astigarraga, Mara Andrés, Elaine S. Jaffe, Elias Campo, Itziar Salaverria

Publikováno v: Haematologica, Vol 104, Iss 9 (2019)

Burkitt-like lymphoma with 11q aberration is characterized by pathological features and gene expression profile resembling those of Burkitt lymphoma but lacks the MYC rearrangement and carries an 11q-arm aberration with proximal gains and telomeric l

Externí odkaz: https://doaj.org/article/39ae097fcf364b2da034aa8f90e33ba8

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Akademický článek

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Whole-body MRI versus an [F-18]FDG-PET/CT-based reference standard for early response assessment and restaging of paediatric Hodgkin's lymphoma

Autor: Bart de Keizer, Federico Verzegnassi, Suzanne Spijkers, Goya Enríquez, Claudio Granata, Auke Beishuizen, Marrie C.A. Bruin, Thomas C. Kwee, Constantino Sábado, Elka Miller, Rutger A.J. Nievelstein, Annemieke S. Littooij, Nelleke Tolboom, Charlotte de Lange

Publikováno v: European Radiology, 31(12), 8925-8936. SPRINGER
Scientia
European Radiology, 31(12), 8925-8936. Springer-Verlag

Objectives To compare WB-MRI with an [18F]FDG-PET/CT-based reference for early response assessment and restaging in children with Hodgkin’s lymphoma (HL). Methods Fifty-one children (ages 10–17) with HL were included in this prospective, multicen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ce90a77385e218e482c26e1c38df7e
https://hdl.handle.net/11370/48702bb2-b42d-45c3-a534-5493f110996b

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Ultrasound criteria (EU-TIRADS) to identify thyroid nodule malignancy risk in adolescents. Correlation with cyto-histological findings

Autor: Diego, Yeste Fernández, Elizabeth, Vega Amenabar, Ana, Coma Muñoz, Larry, Arciniegas Vallejo, María, Clemente León, Marina, Planes-Conangla, Carmela, Iglesias Felip, Constantino, Sábado Álvarez, Gabriela, Guillén Burrieza, Ariadna, Campos-Martorell

Publikováno v: Endocrinología, Diabetes y Nutrición (English ed.). 68:728-734

Thyroid nodule (TN) harbouring a thyroid carcinoma are more common in paediatric than adult patients. In paediatric population, the evaluation of a TN should require specific paediatric tools for its diagnostic and therapeutic management. High-resolu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a1beadadbee321353e9f80fd0ccb38
https://doi.org/10.1016/j.endien.2020.11.006

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Ceritinib in paediatric patients with anaplastic lymphoma kinase-positive malignancies: an open-label, multicentre, phase 1, dose-escalation and dose-expansion study

Autor: Johannes H. Schulte, C. Michel Zwaan, David S. Ziegler, Michela Casanova, Matthias Fischer, Mario Stegert, Beate Wulff, Constantino Sábado, Meredith S. Irwin, Luojun Wang, Birgit Geoerger, Fabrice Branle, Felipe K. Hurtado, Lynley V. Marshall, Lucas Moreno

Publikováno v: The Lancet Oncology, 22(12), 1764-1776. Lancet Publishing Group

Background: Several paediatric malignancies, including anaplastic large cell lymphoma (ALCL), inflammatory myofibroblastic tumour (IMT), neuroblastoma, and rhabdomyosarcoma, harbour activation of anaplastic lymphoma kinase (ALK) through different mec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b69752196c31def7be443e240cab9f0
https://doi.org/10.1016/s1470-2045(21)00536-2

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Criterios ecográficos (EU-TIRADS) para identificar el riesgo de malignidad de los nódulos tiroideos en adolescentes. Correlación con los hallazgos cito-histológicos

Autor: Larry Arciniegas Vallejo, Ana Coma Muñoz, Diego Yeste Fernández, Elizabeth Vega Amenabar, Marina Planes-Conangla, Constantino Sábado Álvarez, Gabriela Guillén Burrieza, María Clemente León, Carmela Iglesias Felip, Ariadna Campos-Martorell

Publikováno v: Endocrinología, Diabetes y Nutrición. 68:728-734

Resumen Introduccion Los nodulos tiroideos (NT) en la edad pediatrica requieren una evaluacion diagnostica completa porque el riesgo de malignidad es mayor con mas frecuencia que en el adulto. La ecografia es la tecnica de imagen clave para decidir l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebf3bbe0fe9b4f0187f3279e094012ae
https://doi.org/10.1016/j.endinu.2020.11.009

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Diverse mutations and structural variations contribute to Notch signaling deregulation in paediatric T-cell lymphoblastic lymphoma

Publikováno v: PEDIATRIC BLOOD & CANCER
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Addi. Archivo Digital para la Docencia y la Investigación

Background T-cell lymphoblastic lymphoma (T-LBL) is an aggressive neoplasm closely related to T-cell acute lymphoblastic leukaemia (T-ALL). Despite their similarities, and contrary to T-ALL, studies on paediatric T-LBL are scarce and, therefore, its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5a34ac099b1565b276d5a6824c6475
http://hdl.handle.net/10810/58291

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Whole-body MRI versus an FDG-PET/CT-based reference standard for staging of paediatric Hodgkin lymphoma: a prospective multicentre study

Autor: Mary Louise C. Greer, Federico Verzegnassi, Marrie C.A. Bruin, Nelleke Tolboom, Tim van de Brug, Charlotte de Lange, Rutger A.J. Nievelstein, Elka Miller, Claudio Granata, Constantino Sábado, Goya Enríquez, Annemieke S. Littooij, Auke Beishuizen, Thomas C. Kwee, Bart de Keizer, Sjoerd G. Elias, Suzanne Spijkers

Publikováno v: European Radiology, 31(3), 1494-1504. Springer-Verlag
European Radiology, 31(3), 1494-1504. Springer Verlag
Spijkers, S, Littooij, A S, Kwee, T C, Tolboom, N, Beishuizen, A, Bruin, M C A, Elias, S G, van de Brug, T, Enríquez, G, Sábado, C, Miller, E, Granata, C, de Lange, C, Verzegnassi, F, Greer, M-L C, de Keizer, B & Nievelstein, R A J 2021, ' Whole-body MRI versus an FDG-PET/CT-based reference standard for staging of paediatric Hodgkin lymphoma: a prospective multicentre study ', European Radiology, vol. 31, no. 3, pp. 1494-1504 . https://doi.org/10.1007/s00330-020-07182-0
European Radiology, 31. SPRINGER
European Radiology

Objectives To assess the concordance of whole-body MRI (WB-MRI) and an FDG-PET/CT-based reference standard for the initial staging in children with Hodgkin lymphoma (HL) Methods Children with newly diagnosed HL were included in this prospective, mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6c88bdde6f435f5608566d6443684a
https://doi.org/10.1007/s00330-020-07182-0

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