Targeting of epigenetic regulators in neuroblastoma

Autor: Luz Jubierre, Carlos Jiménez, Eric Rovira, Aroa Soriano, Constantino Sábado, Luis Gros, Anna Llort, Raquel Hladun, Josep Roma, Josep Sánchez de Toledo, Soledad Gallego, Miguel F. Segura

Publikováno v: Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-12 (2018)

Cancer therapy: Exploring an epigenetic approach Treatments that target chromatin, the combination of DNA and proteins, are emerging as alternative ways to treat aggressive neuroblastomas, cancers of neural tissue. Altering the structure and function

Externí odkaz: https://doaj.org/article/44a3f605201c49468d79e2635c1fc5f8

Ultrasound criteria (EU-TIRADS) to identify thyroid nodule malignancy risk in adolescents. Correlation with cyto-histological findings

Autor: Diego, Yeste Fernández, Elizabeth, Vega Amenabar, Ana, Coma Muñoz, Larry, Arciniegas Vallejo, María, Clemente León, Marina, Planes-Conangla, Carmela, Iglesias Felip, Constantino, Sábado Álvarez, Gabriela, Guillén Burrieza, Ariadna, Campos-Martorell

Publikováno v: Endocrinología, Diabetes y Nutrición (English ed.). 68:728-734

Thyroid nodule (TN) harbouring a thyroid carcinoma are more common in paediatric than adult patients. In paediatric population, the evaluation of a TN should require specific paediatric tools for its diagnostic and therapeutic management. High-resolu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a1beadadbee321353e9f80fd0ccb38
https://doi.org/10.1016/j.endien.2020.11.006

Ceritinib in paediatric patients with anaplastic lymphoma kinase-positive malignancies: an open-label, multicentre, phase 1, dose-escalation and dose-expansion study

Autor: Johannes H. Schulte, C. Michel Zwaan, David S. Ziegler, Michela Casanova, Matthias Fischer, Mario Stegert, Beate Wulff, Constantino Sábado, Meredith S. Irwin, Luojun Wang, Birgit Geoerger, Fabrice Branle, Felipe K. Hurtado, Lynley V. Marshall, Lucas Moreno

Publikováno v: The Lancet Oncology, 22(12), 1764-1776. Lancet Publishing Group

Background: Several paediatric malignancies, including anaplastic large cell lymphoma (ALCL), inflammatory myofibroblastic tumour (IMT), neuroblastoma, and rhabdomyosarcoma, harbour activation of anaplastic lymphoma kinase (ALK) through different mec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b69752196c31def7be443e240cab9f0
https://doi.org/10.1016/s1470-2045(21)00536-2

Whole-body MRI versus an FDG-PET/CT-based reference standard for staging of paediatric Hodgkin lymphoma: a prospective multicentre study

Autor: Mary Louise C. Greer, Federico Verzegnassi, Marrie C.A. Bruin, Nelleke Tolboom, Tim van de Brug, Charlotte de Lange, Rutger A.J. Nievelstein, Elka Miller, Claudio Granata, Constantino Sábado, Goya Enríquez, Annemieke S. Littooij, Auke Beishuizen, Thomas C. Kwee, Bart de Keizer, Sjoerd G. Elias, Suzanne Spijkers

Publikováno v: European Radiology, 31(3), 1494-1504. Springer-Verlag
European Radiology, 31(3), 1494-1504. Springer Verlag
Spijkers, S, Littooij, A S, Kwee, T C, Tolboom, N, Beishuizen, A, Bruin, M C A, Elias, S G, van de Brug, T, Enríquez, G, Sábado, C, Miller, E, Granata, C, de Lange, C, Verzegnassi, F, Greer, M-L C, de Keizer, B & Nievelstein, R A J 2021, ' Whole-body MRI versus an FDG-PET/CT-based reference standard for staging of paediatric Hodgkin lymphoma: a prospective multicentre study ', European Radiology, vol. 31, no. 3, pp. 1494-1504 . https://doi.org/10.1007/s00330-020-07182-0
European Radiology, 31. SPRINGER
European Radiology

Objectives To assess the concordance of whole-body MRI (WB-MRI) and an FDG-PET/CT-based reference standard for the initial staging in children with Hodgkin lymphoma (HL) Methods Children with newly diagnosed HL were included in this prospective, mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6c88bdde6f435f5608566d6443684a
https://doi.org/10.1007/s00330-020-07182-0

Long-term follow-up of differentiated thyroid carcinoma in children and adolescents

Autor: Constantino Sábado Álvarez, Joan Castell Conesa, Montserrat Negre Busó, Gemma Cuberas Borrós, María Boronat-de Ferrater, Pere Galofré Mora, Marc Simó Perdigó, Amparo García Burillo

Publikováno v: Journal of Pediatric Endocrinology and Metabolism. 33:1431-1441

Objectives The aims were to analyze the clinical features, response to treatment, prognostic factors and long-term follow-up of children and adolescents with differentiated thyroid carcinoma (DTC). Methods Eighty patients with DTC were studied retros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75effe821d395284c45257dc42b51564
https://doi.org/10.1515/jpem-2020-0194