Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Constantine D Troupes"'
Autor:
Matthew A Schechter, Michael K H Hsieh, Linda W Njoroge, J Will Thompson, Erik J Soderblom, Bryan J Feger, Constantine D Troupes, Kathleen A Hershberger, Olga R Ilkayeva, Whitney L Nagel, Gina P Landinez, Kishan M Shah, Virginia A Burns, Lucia Santacruz, Matthew D Hirschey, Matthew W Foster, Carmelo A Milano, M Arthur Moseley, Valentino Piacentino, Dawn E Bowles
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104157 (2014)
The molecular differences between ischemic (IF) and non-ischemic (NIF) heart failure are poorly defined. A better understanding of the molecular differences between these two heart failure etiologies may lead to the development of more effective hear
Externí odkaz:
https://doaj.org/article/97d4172e41884dda9d397f4cdd8030bd
Autor:
Yijun Yang, Jaslyn Johnson, Constantine D. Troupes, Eric A. Feldsott, Lindsay Kraus, Emily Megill, Zilin Bian, Ngefor Asangwe, Tabito Kino, Deborah M. Eaton, Tao Wang, Marcus Wagner, Lena Ma, Christopher Bryan, Markus Wallner, Hajime Kubo, Remus M. Berretta, Mohsin Khan, Hong Wang, Raj Kishore, Steven R. Houser, Sadia Mohsin
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102909- (2023)
Few therapies have produced significant improvement in cardiac structure and function after ischemic cardiac injury (ICI). Our possible explanation is activation of local inflammatory responses negatively impact the cardiac repair process following i
Externí odkaz:
https://doaj.org/article/f68a1e3939344780bdcabe697059e9a3
Autor:
Markus Wallner, Chen Zhang, Sadia Mohsin, Danielle M. Trappanese, Steven R. Houser, Giulia Borghetti, Remus M. Berretta, Thomas E. Sharp, Xiongwen Chen, Constantine D Troupes, Xiaoxiao Zhang, Yijun Yang, Polina Gross, Eric Feldsott, Neil Zalavadia, Amir Toib, Shavonn C. Harper, Hajime Kubo
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 313:H620-H630
Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases and among the leading causes of sudden cardiac death (SCD) in the young. The cellular mechanisms leading to SCD in HCM are not well known. Prolongation of the action
Autor:
Dirk von Lewinski, Constantine D Troupes, Giulia Borghetti, Steven R. Houser, Jonathan Soboloff, Hajime Kubo, Xiongwen Chen, Sadia Mohsin, Remus M. Berretta, Chen Zhang, Markus Wallner
Publikováno v:
Circulation Research. 121:125-136
Rationale: Pathological increases in cardiac afterload result in myocyte hypertrophy with changes in myocyte electrical and mechanical phenotype. Remodeling of contractile and signaling Ca 2+ occurs in pathological hypertrophy and is central to myocy
Autor:
Erhe Gao, Mohsin Khan, Austin Borden, Constantine D Troupes, Yijun Yang, Sadia Mohsin, Raj Kishore, Anna Maria Lucchese, Justin Kurian, Jessica Ibetti, Walter J. Koch, Emily Nickoloff, Steven R. Houser
Publikováno v:
Circulation research. 125(1)
Rationale: Embryonic heart is characterized of rapidly dividing cardiomyocytes required to build a working myocardium. Cardiomyocytes retain some proliferative capacity in the neonates but lose it in adulthood. Consequently, a number of signaling hub
Autor:
Rhonda Bassel-Duby, Eric N. Olson, Fenfen Wu, John R. McAnally, Constantine D Troupes, Stephen C. Cannon, Douglas M. Anderson, Ege T. Kavalali, Steven R. Houser, Catherine A. Makarewich, Benjamin R. Winders, Austin L Reese, Benjamin R. Nelson, Xiongwen Chen
Publikováno v:
Science (New York, N.Y.), vol 351, iss 6270
Another micropeptide flexes its muscle Genome annotation is a complex but imperfect art. Attesting to its limitations is the growing evidence that certain transcripts annotated as long noncoding RNAs (lncRNAs) in fact code for small peptides with bio
Autor:
Neil Zalavadia, Shavonn C. Smith, Sadia Mohsin, Remus M. Berretta, Yan Zhou, Jason M. Duran, Thomas E. Sharp, Timothy Starosta, Hajime Kubo, Steven R. Houser, Constantine D Troupes, Elorm J Agra
Publikováno v:
Circulation Research. 117:1024-1033
Rationale: Adoptive transfer of multiple stem cell types has only had modest effects on the structure and function of failing human hearts. Despite increasing the use of stem cell therapies, consensus on the optimal stem cell type is not adequately d
Autor:
Steven R. Houser, Justin Kurian, Mohsin Khan, Raj Kishore, Austin Borden, Sadia Mohsin, Constantine D Troupes, Yijun Yang, Emily Nickoloff
Publikováno v:
Circulation Research. 123
Rationale: Embryonic heart is characteristic of rapidly dividing cardiomyocytes required to build a working myocardium. Cardiomyocytes retain some proliferative capacity in the neonates but lose most of it in adulthood. Consequently, a number of sign
Autor:
Catherine A. Makarewich, Steven R. Houser, David L. Crandall, Walter J. Koch, Polina Gross, Constantine D Troupes, Sarah M. Schumacher
Publikováno v:
Journal of Molecular and Cellular Cardiology. 86:179-186
Rationale There is a current need for the development of new therapies for patients with heart failure. Objective We test the effects of members of the corticotropin-releasing factor (CRF) family of peptides on myocyte contractility to validate them
Autor:
Hajime Kubo, Steven R. Houser, Constantine D Troupes, Mohsin Khan, Jaslyn Johnson, Timothy Starosta, Yijun Yang, Sadia Mohsin, Jennifer Petovic, Remus M. Berretta
Publikováno v:
Circulation Research. 119
Rationale: Cortical bone derived stem cells (CBSCs) are known to have improved growth kinetics and myocardial repair properties that are superior to other known stem cell types used. Salutary effects of CBSCs in large are mediated by paracrine secret