Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Constantine Bitsaktsis"'
Autor:
Brian J. Franz, Ying Li, Constantine Bitsaktsis, Bibiana V. Iglesias, Giang Pham, Raju Sunagar, Sudeep Kumar, Edmund J. Gosselin
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. Thus, the generation of Ag-specific IgG in response to infection or immuniz
Externí odkaz:
https://doaj.org/article/299949b81aee4386ba48c654c6fa9881
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129981 (2015)
Production of pro-inflammatory cytokines by innate immune cells at the early stages of bacterial infection is important for host protection against the pathogen. Many intracellular bacteria, including Francisella tularensis, the agent of tularemia, u
Externí odkaz:
https://doaj.org/article/fb3711ba6cc0403a9a598bd910c177f9
Autor:
Tiffany M Zarrella, Anju Singh, Constantine Bitsaktsis, Tabassum Rahman, Bikash Sahay, Paul J Feustel, Edmund J Gosselin, Timothy J Sellati, Karsten R O Hazlett
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22335 (2011)
The gram-negative bacterium Francisella tularensis survives in arthropods, fresh water amoeba, and mammals with both intracellular and extracellular phases and could reasonably be expected to express distinct phenotypes in these environments. The pre
Externí odkaz:
https://doaj.org/article/d26e982887ab4c3e88ea0d1b47b2e207
Autor:
Andrieh Darwich, Rachel A. Montel, Keith Smith, Eugenia Dziopa, Robert Korngold, Dante B. Descalzi-Montoya, Zheng Yang, Constantine Bitsaktsis, David Sabatino
Publikováno v:
Chembiochem
De novo cancer-targeting immunostimulatory peptides have been designed and developed as synthetic antibody mimics. A series of bifunctional peptides incorporating NKp30-binding and NK-cell-activating domains were synthesized as linear dimers and then
Autor:
Zaher Merhi, AshiniR Dias, Constantine Bitsaktsis, Daniella Emdin, Lisa Bosman, AndreHugo Smith
Publikováno v:
Medical Gas Research.
Publikováno v:
Vaccine. 38(35)
Streptococcus pneumoniae (Spn) remains a considerable threat to public health despite the availability of antibiotics and polysaccharide conjugate vaccines. The lack of mucosal immunity in addition to capsular polysaccharide diversity, has proved to
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research SocietyREFERENCES. 38(8)
Fracture repair is a complex process requiring heterotypic interactions between osteogenic cells and immune cells. Recent evidence indicates that macrophages are critically involved in fracture repair. Polarized macrophage populations differentially
Publikováno v:
Biopolymers. 106:658-672
The rise of biologics that can stimulate immune responses towards the eradication of tumors has led to the evolution of cancer-based immunotherapy. Representatively, B7H6 has been recently identified as a protein ligand on tumor cells that binds spec
Autor:
Constantine Bitsaktsis, Kari Wiedinger
Publikováno v:
The Journal of Immunology. 204:168.11-168.11
Streptococcus pneumoniae (Spn) remains a considerable threat to public health despite the availability of antibiotics and polysaccharide conjugate vaccines. The lack of mucosal immunity in addition to capsular polysaccharide diversity, has proved to
Publikováno v:
Therapeutic Advances in Vaccines. 3:155-163
Objectives: Previous studies have demonstrated that intranasal administration of inactivated (fixed) Francisella tularensis ( iFt) live vaccine strain (LVS) in conjunction with the mucosal adjuvant, cholera toxin B (CTB), provides full protection aga