Circulating Autoantibodies Recognizing Immunodominant Epitopes From Human Apolipoprotein B Associate With Cardiometabolic Risk Factors, but Not With Atherosclerotic Disease

Autor: Timoteo Marchini, Sara Malchow, Lourdes Caceres, Abed Al Hadi El Rabih, Sophie Hansen, Timothy Mwinyella, Lisa Spiga, Sven Piepenburg, Hauke Horstmann, Tijani Olawale, Xiaowei Li, Lucia Sol Mitre, Mark Colin Gissler, Heiko Bugger, Andreas Zirlik, Timo Heidt, Ingo Hilgendorf, Peter Stachon, Constantin von zur Muehlen, Christoph Bode, Dennis Wolf

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

RationaleAtherosclerosis is a chronic inflammatory disease of large arteries that involves an autoimmune response with autoreactive T cells and auto-antibodies recognizing Apolipoprotein B (ApoB), the core protein of low-density lipoprotein (LDL). He

Externí odkaz: https://doaj.org/article/b836ef0458e64f10b7c8104c4996cc57

Outcome Prediction in Patients with Severe COVID-19 Requiring Extracorporeal Membrane Oxygenation—A Retrospective International Multicenter Study

Autor: Alexander Supady, Jeff DellaVolpe, Fabio Silvio Taccone, Dominik Scharpf, Matthias Ulmer, Philipp M. Lepper, Maximilian Halbe, Stephan Ziegeler, Alexander Vogt, Raj Ramanan, David Boldt, Stephanie-Susanne Stecher, Andrea Montisci, Tobias Spangenberg, Olivier Marggraf, Chandra Kunavarapu, Lorenzo Peluso, Sebastian Muenz, Monica Buerle, Naveen G. Nagaraj, Sebastian Nuding, Catalin Toma, Vadim Gudzenko, Hans Joachim Stemmler, Federico Pappalardo, Georg Trummer, Christoph Benk, Guido Michels, Daniel Duerschmied, Constantin von zur Muehlen, Christoph Bode, Klaus Kaier, Daniel Brodie, Tobias Wengenmayer, Dawid L. Staudacher

Publikováno v: Membranes, Vol 11, Iss 3, p 170 (2021)

The role of veno-venous extracorporeal membrane oxygenation therapy (V-V ECMO) in severe COVID-19 acute respiratory distress syndrome (ARDS) is still under debate and conclusive data from large cohorts are scarce. Furthermore, criteria for the select

Externí odkaz: https://doaj.org/article/2e0f85d5add24450b6aff902b11093a3

Elevated platelet-leukocyte complexes are associated with, but dispensable for myocardial ischemia-reperfusion injury

Autor: Christopher Starz, Carmen Härdtner, Maximilian Mauler, Bianca Dufner, Natalie Hoppe, Katja Krebs, Carolin Anna Ehlert, Julian Merz, Timo Heidt, Peter Stachon, Dennis Wolf, Christoph Bode, Constantin von zur Muehlen, Wolfgang Rottbauer, Meinrad Gawaz, Daniel Duerschmied, Florian Leuschner, Oliver Borst, Dirk Westermann, Ingo Hilgendorf

Publikováno v: Basic research in cardiology. 117(1)

Aims P-selectin is an activatable adhesion molecule on platelets promoting platelet aggregation, and platelet–leukocyte complex (PLC) formation. Increased numbers of PLC are circulating in the blood of patients shortly after acute myocardial infarc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1be2bb39c3fe46a1bbc83c75cf1646
https://pubmed.ncbi.nlm.nih.gov/36383299

Evaluation of Serum Serotonin as a Biomarker for Myocardial Infarction and Ischemia/Reperfusion Injury

Autor: Lukas Andreas Heger, Ingo Ahrens, Rosmarie Laumann, Christoph B. Olivier, Constantin von zur Muehlen, Marina Rieder, Achim Lother, Daniel Duerschmied, Marcus Hortmann, Christoph Bode, Thilo Witsch, Nancy Schanze

Publikováno v: Applied Sciences, Vol 10, Iss 6379, p 6379 (2020)
Applied Sciences
Volume 10
Issue 18

Background: Activated platelets release serotonin during acute myocardial infarction (AMI), aggravating myocardial damage and ischemia/reperfusion (I/R) injury. However, serum serotonin and its potential role as a biomarker for myocardial infarction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772878e2e2649f04d2f554c9d6c5ea99
https://www.mdpi.com/2076-3417/10/18/6379

Imaging assessment of bioresorbable vascular scaffolds

Autor: Ken Kozuma, Erhan Tenekecioglu, Constantin von zur Muehlen, Takayuki Okamura, Kengo Tanabe, Yuki Ishibashi, Yukio Ozaki, Yuki Katagiri, Taku Asano, Hiroki Tateishi, Pannipa Suwannasom, Patrick W. Serruys, Yoshinobu Onuma, Yosuke Miyazaki, Yohei Sotomi, Carlos Collet, Takashi Muramatsu, Shimpei Nakatani

Publikováno v: Cardiovascular intervention and therapeutics, 33(1), 11-22. Springer Verlag
Cardiovascular Intervention and Therapeutics, 33(1), 11-22. Springer-Verlag

Vascular reparative therapy has become a reality with bioresorbable scaffolds (BRSs). To assess acute and long-term performance of the device, multimodality imaging would be essential. Radiopacity of metal hinders the imaging assessment, whereas radi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95e5539ab31d02b457bd55fe996d20e
https://pure.eur.nl/en/publications/17c1c272-b019-4dbd-9384-30c402a42827